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320 articles for “cause”
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Effectiveness of a Planned Teaching Programme on Primigravid Mothers' Awareness of Specific Natural Pain Relief Techniques Used During Labor in Particular Bangalore Hospital
Abstract: Background: Pain is an exciting sensation and is caused by the stimulus during labor. Always Pain plays a major role in labor in empowering the women, whereby they triumph by giving delivery to the newborn. Objectives: Assess the knowledge level about selected natural pain relief methods. Methodology: A quantitative research approach and the design used in this study was a pre-experimental research design. Sixty primigravid mothers were selected for the …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 9–16 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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Stress Level and Coping Strategies Among the Students Preparing for Common Entrance Test in Coaching Classes of a Selected City
Abstract: Stress is a natural response of your body to any type of demand, whether it is a positive or negative experience. When individuals experience stress due to external factors, their bodies release chemicals into the bloodstream, which can be beneficial if the stress is caused by physical danger. However, if the stress is a result of an emotional situation and there is no way to channel this additional energy and …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–21 Read article
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Strategies for Flood Mitigation
Abstract: The world has always experienced change. Water-too much or too little is the most common cause of migration and a city's downfall. The notable and significant distinction right now is that we are seeing it in real-time for the first time in human history. We contributed to the dangers that were produced, and we contributed to the remedies that will influence the pace and scope of change and disruption. We …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Heart Attack Prediction Using Machine Learning
Abstract: Heart attacks have become a prevalent and serious condition in recent years due to a variety of causes. Numerous variables, including age, sex, fat, and others, can be used to predict it. In the current study, it was found that a data set with 13 parameters and 302 distinct data values, collected from a Kaggle dataset to assess patient condition, was covered. This article delves into the application of machine …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 8–13 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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A Security Investigation Survey of Ransomware Detection and Avoidance Strategies for IoT Networks
Abstract: The internet of things (IoT) refers to the interconnection of a large number of distinct physical objects, which in turn makes possible a variety of services and applications. Because the IoT sector is developing at such a rapid rate, ensuring its safety ought to be a high concern. At this time, ransomware attacks constitute the biggest danger to IoT posed by cyberattacks. Ransomware is software that blocks access to or …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 14–23 Read article
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Study of Blended Learning of Artificial Intelligence in Cybersecurity
Abstract: Nowadays there are huge applications of internet of things, and cyberattacks are causing concern all over world. To avoid cyberattacks, designing cybersecurity approach is today’s basic need. Artificial intelligence has appeared as a powerful tool in the domain of cybersecurity and can be tuned to deal with cybersecurity and cyberthreats. Cybersecurity is an incredibly growing field since the past decade, there are many applications based on cybersecurity, eventually threats are …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 1–6 Read article
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How Does the World Deal with E-waste? Its Management and Analysis
Abstract: There are numerous electrical devices used daily. Whether we do it knowingly or unknowingly, we always appreciate how much easier life is as a result. But as we all know that everything nice eventually comes to an end, these gadgets inevitably stop working and are wasted. One of them claims that electronic garbage, or “E-waste”, is a global issue that is only becoming worse. A significant buildup of e-waste is …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 1, 2023 · pp. 11–16 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Evidence for Forward Spin and Reverse Spin Radio Photons
Abstract: We generated alternate spin radio frequency photons by accelerating metallic valence electrons in a wire with half portions of a sine wave. To avoid standing waves from sinusoidal movement, a non-resonating transmitter was built with a non-resonating antenna. An oscilloscope at a second non-resonant receiving antenna 3 wavelengths away from the transmitter detected positive going 180-degree voltage pulses. Reversing the direction of electron excitation in the transmitter antenna caused negative …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 1, 2023 · pp. 1–12 Read article
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Deadlock Controlling Algorithms for Distributed Database Systems
Abstract: When the demand for a system resource exceeds the system's capacity, deadlock – an operating system problem – results. The problem of deadlock frequently causes a distributed database's performance to lag. This research critically examined two types of deadlock problems that have an impact on a distributed database's performance. Transaction control and transaction location deadlock difficulties were the specific challenges that the article specifically addressed. In this paper, deadlock prevention …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 2, 2023 · pp. 10–17 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article