Search
143 articles for “Type 2 diabetics”
-
Effect of Patient Counseling in Improving Physical and Mental Health of Type-2 Diabetes Mellitus Patients
Abstract: Diabetes mellitus is a heterogeneous metabolic disorder characterized by chronic hyperglycemia with insulin hypo-secretion or insulin insensitivity. Despite the availability of treatment, diabetes has remained a major cause of death. The main goal of any medical care is the improvement of the patients’ overall quality of life. The aim of this paper was to assess the impact of pharmacist provided patient counseling on physical and mental health outcomes in type-2 …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 2, 2014 · pp. 16–19 Read article
-
A short review on scenario of Type 1 diabetes in Australia
Abstract: Type 1 diabetes (T1D) is caused by an autoimmune attack on pancreatic beta cells that leads to insulin deficiency. The incidence of T1D in Australia has doubled over the past 20 years. T1D treatment focuses on physiological insulin replacement, aiming for near-normal blood glucose levels. Morbidity and mortality result in hypoglycemia in T1D. Better results can be achieved by following some of the new technologies which includes insulin pumps, continuous …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 1–5 Read article
-
Activity of Cannabinoids in Type II Diabetes
Abstract: The present research is a theoretical study of the medicinal use of Cannabis (cannabinoids) compounds in Type II Diabetes based on literature citing animal models and available clinical evidence from human studies. The study emphasizes the positive physiological actions and benefits of cannabinoid compounds in Type II Diabetes. The pharmacological activities of cannabinoid compounds in Type II Diabetes have been studies only in limited human clinical trials that were often …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 2, 2017 · pp. 1–5 Read article
-
Computational Identification of Protein Tyrosine Phospatase-1B (PTP-1B) Inhibitors for Checking Type II Diabetes
Abstract: Protein tyrosine phosphatases (PTPs) are a family of enzyme that comprises of about 100 proteins which catalyze dephosphorylation of phosphotyrosine residues in protein substrates. Phosphotyrosine is a central element in cell signaling, and its activity is essential for cellular homeostasis and for appropriate responses to extracellular signals. PTP-1B antagonizes insulin signaling by reducing the activation state of the insulin receptor kinase, thereby inhibiting post-receptor signaling in insulin responsive tissue. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 21–25 Read article
-
Clinical Implications of Serum NT-pro Brain Natriuretic Peptides in Type1 Diabetes with Positive Antiviral Antibodies
Abstract: Subclinical cardiovascular disease is common in diabetes mellitus and is associated with an increased risk of cardiovascular events including heart failure. This study was aimed to assess the association of NT-proBNP as a marker of heart failure and antiviral antibodies in patients with type 1 diabetes mellitus (T1D). One hundred and forty-seven T1D patients (65 male and 82 female) and 24 (11 male and 13 female) non-diabetic control subjects were …
Published in Research and Reviews: A Journal of Medicine · Vol. 3, Issue 1, 2013 · pp. 12–16 Read article
-
A Review of Psychoendocrine Morbidity: Co-occurring Diabetes Type-II (DIAII), Bipolar II Disorder (BPII), and Obsessive-Compulsive Disorder (OCD)
Abstract: The acute phase of (Bipolar II Disorder) BPII encompasses a psychosis of dramatic mood changes and elevated energy levels often accompanied by co-occurring psychiatric and systemic disorders. The co-occurring disorders (i.e., BPII, DIAII, and OCD) are accentuated, most often by the metabolic imbalances of (Diabetes Type-II) DIAII and sometimes by the psychiatric condition of (Obsessive-Compulsive Disorder) OCD. Increased morbidity and mortality of the co-occurring disorders dominates the chronic course of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 2, 2016 · pp. 19–23 Read article
-
Patterns and Risk Factors of Gestational Diabetes Mellitus among Mothers Who Visited Antenatal Clinics in Public Health Centers of Mekelle City, Tigray, Ethiopia, 2015
Abstract: Gestational diabetes mellitus is associated with significant morbidity in the short and long-term, for both mother and offspring. It is now well established that women with a history of GDM are at a significant increased risk of developing type-2 diabetes, later in life. There were limited studies conducted on pattern and risk factors of gestational diabetes mellitus in Tigray region. The aim of this study is to assess patterns and …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 2, 2016 · pp. 12–20 Read article
-
Microalbuminuria and Other Risk Factors in Diabetic Retinopathy
Abstract: The objective of this paper was to study positivity of microalbuminuria and other risk factors in DM type II and their relation to DR.An analytic study was done among 300 selected cases of Type 2 DM in one year. The grading of the severity of DR was done using ETDRS protocol. Tests for hemoglobin, fasting blood sugars, micro-albuminuria, glycated hemoglobin (HbA1c) and lipid profile were done. 137 (45.67%) cases of …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 2, 2014 · pp. 26–32 Read article
-
A Study on The Combined Effectiveness of Cognitive Training and Multisensory Approaches on Improving Balance and Gait in Type II Diabetic Neuropathy
Abstract: Aim: The aim of the present study was to determine the combined effectiveness of Cognitive Training (CT) and Multisensory (MS) Approaches on improving balance and gait in type II diabetic neuropathy. Purpose: One of the most prevalent consequences of diabetes mellitus is neuropathy. Intrinsic foot muscle weakness may cause a change in gait, loss of balance, and the potential to fall due to diabetic polyneuropathy, which affects the nervous system's …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 29–40 Read article
-
Challenges in Diabetes Management Barriers and Support Systems in North India
Abstract: Background: The prevalence of Diabetes mellitus is ever growing in India and management of the disease is hindered by socio-economic, healthcare, and psychosocial barriers. Insofar as economic and social barriers pose challenges ranging from limited access to medical care, social stigma, specialist support leading to improper glycemic control, which is a strong predictor for diabetes complications, morbidity and mortality. Moreover, developing an understanding of systemic challenges and available supports is …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
-
‘Betazen’ Herbal Formulation, Ameliorates Experimentally Induced Metabolic Disturbances in Insulin Resistant Rats
Abstract: The present study was designed to evaluate anti-diabetic activity of ayurvedic formulation ‘Betazen’ in experimentally induced insulin resistant rats. Wistar rats were being rendered insulin resistant by administration of dexamethasone (2 μg/day s.c), along with high fat-high sugar (HFHS) diet (i.e. vanaspati ghee and fructose enriched) for 42 days. Animals with fasting blood glucose levels (BGL) of more than 150 mg/dl were selected, divided into different groups and administered 2.7 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 13–23 Read article
-
Simple, Direct and Stability-Indicating UV Spectrophotometric Assay of Pioglitazone Hydrochloride in Pharmaceuticals
Abstract: Pioglitazone hydrochloride (PGH) is an antihyperglycemic agent used in the treatment of type-2 diabetes mellitus. A simple and straight forward UV-spectrophotometric method is presented for the determination of PGH in bulk drug and tablets by measuring the absorbance of drug solution in 0.1M H2SO4 at 269 nm. A plot of absorbance versus concentration obeyed Beer’s law over 2–36 µg ml-1 concentration range (r = 0.9981) with a molar absorptivity of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 7–16 Read article
-
Microalbuminuria as an Independent Screening Tool in Patients with Myocardial Infarction
Abstract: Acute Myocardial Infarction (AMI) is a condition in which there is an inadequate supply of blood and oxygen to a portion of myocardium; most common cause being atherosclerosis of coronary vessels. Microalbuminuria (MAU) is defined as urinary albumin-to-creatinine ratio (UACR) of 30–300 mg/g. It is considered as marker of generalized endothelial dysfunction and vasculopathy and suggested to contribute to the formation of atherosclerotic lesion and ultimately leading to risk of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 2, 2017 · pp. 41–45 Read article
-
An Evaluation of Effects of Type-II Diabetes Mellitus on Salivary Flow Rate and Some Salivary Parameters (Total Protein, Glucose, and Amylase) in a Tertiary Care Hospital in Uttar Pradesh, India
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Objective of this study is to evaluate the constituents of salivary total protein, glucose and amylase about their alterations in diabetics as compared to healthy subjects. Salivary flow rate, salivary total protein, glucose, and amylase were measured in 225 subjects, 75 in each uncontrolled diabetes, controlled diabetes and healthy non-diabetics. A lower level of salivary glucose was observed among healthy subjects …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 2, 2013 · pp. 1–7 Read article
-
Development and Characterization of Mucoadhesive Microspheres Containing a Model Antidiabetic Drug
Abstract: The present work was envisaged to reduce the dosing frequency and improve patient compliance by designing and evaluating sustained release mucoadhesive (SRM) microspheres of metformin hydrochloride (MH) for an effective control of diabetes type-2. Microspheres were prepared by emulsification solvent evaporation method using sodium alginate, carbopol 934P (CP), and sodium carboxy methyl cellulose (SCMC) as a mucoadhesive polymers. The microspheres exhibits good mucoadhesive properties and showed high drug entrapment efficiency. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 2, 2015 · pp. 12–19 Read article
-
Development of a Polymeric Detection System for Salivary Annexin-1: A Potential Tool for Point-of-Care Diagnostics in Periodontal Disease
Abstract: Salivary annexin-1, a protein with anti-inflammatory properties, has emerged as a potential biomarker for periodontal disease. However, current detection methods, like ELISA, are often complex and require laboratory settings. This study explores the development of a novel polymeric detection system for the rapid and sensitive identification of salivary annexin-1. This system could leverage the unique properties of polymers to create a point-of-care diagnostic tool for: (1) early detection and monitoring …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 101–110 Read article
-
Therapeutic Potential of Plant-Derived Phytochemicals in Targeting Receptor Pathways Related to Non-Enzymatic Glycation: A Meta-Analysis
Abstract: Background: Non-enzymatic glycation, where reducing sugars react with proteins, lipids, and nucleic acids, contributes to various pathological conditions, such as diabetic complications and cardiovascular diseases. This process is facilitated by the receptor for advanced glycation end-products (RAGE), which is pivotal in driving inflammation and causing tissue damage. Objective: This meta-analysis evaluates the effects of plant-derived phytochemicals on RAGE expression and associated signaling pathways, assessing their therapeutic potential in glycation-related diseases. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 60–73 Read article
-
Determination of the Antidiabetic Drug Miglitol in Pharmaceuticals by Ultra-Performance Liquid Chromatography
Abstract: Miglitol (MGL) is a drug used in the treatment of type-2 diabetes mellitus. A new analytical method employing ultra-performance liquid chromatography (UPLC) with UV-detection is presented for the determination of MGL in bulk drug and tablet forms. Analysis was performed in less than 3 min in isocratic mode on a reversed phase BEH C18 (100 mm × 2.1 mm; 1.7 µm particle size) column using phosphate buffer of pH 3.7-acetonitrile …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 2, 2018 · pp. 11–26 Read article
-
Efficient Identification of Complex Diseases Through Epistasis Computational Models: A Review
Abstract: AbstractGenome-Wide Association Studies (GWAS) identify and characterize the genes that are associated with human diseases. One of the significant ongoing researches in GWAS is to identify the disease susceptible genes through Epistasis. The gene that masks the effects of other genes is called Epistasis. The gene interacts with another gene is known as epistatic or genetic interactions (GGIs). GWAS identifies the genetic variants of Single Nucleotide Polymorphism and also the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 21–32 Read article
-
A Comparative Study on Detection of Different Disease Using KNN
Abstract: Nowadays many approaches are made to detect or predict any disease in human body using different data mining techniques. This paper is an approach to study K-nearest neighbor (KNN) classification technique used in different disease prediction. Nowadays number of diseases are needed to be classified and are threat to the human life. Here KNN approach on disease are tuberculosis, heart disease, diabetes, chronic renal failure, neuromuscular disease and brain MRI …
Published in Journal of Open Source Developments · Vol. 5, Issue 3, 2018 · pp. 11–16 Read article