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188 articles for “Resistance”
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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A Review Paper on Friction Stir Processing on Aluminium Alloys
Abstract: Friction stir processing is a step from friction stir welding, targeted at surface modification through improving the local microstructure via localized plastic deformation. The tool consists of a rotating mechanism incorporating a shoulder and pin that are inserted into the material, traversing the designated area. When the tool's shoulder and the workpiece make contact, friction develops, generating heat that produces plastic deformation. This localized plastic deformation and heat impact result …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Extended Spectrum Beta-Lactamase Production By Acinetobacter baumannii Isolated From Hospital Environment
Abstract: Extended spectrum β-lactamases production was determined by Double Disc synergy test for twenty one bacterial isolates of Acinetobacter bumannii isolated from the hospital environment. This study investigates the prevalence, genetic mechanisms, and clinical implications of ESBL production by A. baumannii. We employed molecular techniques to identify and characterize ESBL genes in clinical isolates, alongside evaluating their susceptibility profiles against a range of antibiotics. These resistant strains were notably associated with …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 71–78 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Defensive Mechanisms and Key Strategies with Its Specified Role in Mulberry Silkworm (Bombyx mori L.)
Abstract: Silkworms (Bombyx mori L.) possess a variety of defense mechanisms that play a vital role in protecting them against microbial infections and environmental stressors. These defense systems are primarily innate, relying on cellular and humoral responses. Cellular defenses include hemocytes which are responsible for processes like phagocytosis, encapsulation, and nodule formation. Humoral responses involve the production of antimicrobial peptides (AMP’s), such as cecropins, moricins, and lysozymes, which target invading pathogens. …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 10–14 Read article
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Preserving Saccharomyces cerevisiae Culture for Bee Health and Production
Abstract: Saccharomyces cerevisiae, a single-celled fungus also known as baker’s and brewer’s yeast, is extensively used in brewing, baking, and winemaking due to its robust genetics and utility as a model organism in scientific research. Its role extends beyond these applications into apiculture, where it is utilized to produce supplements and pollen replacements for honeybees. These yeast-based supplements are crucial, especially during times of pollen scarcity or colony stress, as they …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
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Stingless Honeybee’s Rare Sugar and PCSK 9 - LDLR Interaction, A New Hope for Hormone Dependent Breast Cancer Patients – An In-silico Study
Abstract: Hypercholesterolemia is a lipid disorder characterized by elevated levels of low-density lipoprotein (LDL), commonly known as "bad" cholesterol. This condition is a significant risk factor in the development and progression of hormone-dependent breast cancer, as well as in the emergence of resistance to hormonal therapy. One of the key regulators of cholesterol metabolism is the proprotein convertase subtilisin/kexin type-9 (PCSK9) protein, which facilitates the degradation of the LDL receptor (LDLR) …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Innovative Porcelain Insulators: Prolonged Durability and Anti-Contamination Efficiency via Nano-TiO2 Photocatalyst Integration
Abstract: Porcelain has long been a critical material in high-voltage electrical insulation due to its exceptional mechanical, thermal, and dielectric properties. However, environmental contamination and material degradation over time pose significant challenges to its durability. This study investigates the integration of nano-sized titanium dioxide (TiO2) photocatalyst coatings on porcelain insulators to enhance their performance and prolong their operational lifespan. Local clay compositions were analyzed, and a comparative study of untreated and …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 18–23 Read article
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Molecular Docking of Saraca asoca (Ashoka) Phytocompounds for Ovarian Cancer Therapy
Abstract: Objective: One of the top five cancers that causes death in women is ovarian cancer, with increases awareness till date the rate of survival is unpredictable. Even though there are advance treatments introduced, chemotherapy is most suggested to the ovarian cancer patients but the rate of relapses increased and the tumors get resistant towards the drugs. This present study is to evaluate the interaction of phytocompounds from Saraca asoca an …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 27–35 Read article
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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Designing a Disaster Resilient Community in Flood prone zones of Srinagar, Uttarakhand.
Abstract: Uttarakhand, a state that scuffles with the dual challenges of climate change and rapid development, is particularly vulnerable to devastating floods. This research delves into the critical issue of strengthening community resilience against such disasters. By examining the interconnected factors of preparedness, mitigation, and response, the study aims to develop a robust framework for safeguarding lives and livelihoods in flood-prone regions. A cornerstone of this research is the exploration of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 2, 2024 · pp. 8–19 Read article
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Maximizing Flow and Ensuring Leak Tightness Through Design and Development of a Unidirectional Check Valve
Abstract: The check valve market, valued at USD 6.5 billion in 2024, is expected to grow at a 4.1% CAGR. Challenges in valve seat materials, particularly SS304 and PTFE (Teflon), contribute to a 0.5% leak rate, which leads to helium gas loss, reduced efficiency, and higher operational costs. While various sealing techniques, including hard-on-soft methods, have been explored, few have been applied to poppet check valves. This study focuses on improving …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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From Molecular Mechanics to Nanocomposites: Engineering Polytetrafluoroethylene (PTFE) for High-performance Coating Applications
Abstract: Polytetrafluoroethylene (PTFE) exhibits remarkable chemical inertness, hydrophobicity, antifriction, self-lubrication, and high-temperature resilience, making it an ideal polymer for various industrial applications, including coatings for medical implants, machinery parts, and corrosion-resistant structures. This study presents a comprehensive analysis of PTFE’s structural properties, focusing on helix reversals within its helical carbon-fluorine chains and their effects on mechanical behavior. The phase transitions of PTFE at temperatures from ambient to high (198°C and above) …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 14–19 Read article
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Significance of Composite Materials for Making Better Future Society
Abstract: Since in the beginning of human history, Materials had been started in use. We can't imagine our world without materials. In fact, Materials has taken centre position in many developed and developing countries. The materials that humans have chosen to use for engineering projects throughout history, including the Stone, Iron, and Silicon ages. However, in order to meet today's difficulties, new materials must be discovered and developed with the necessary …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 56–62 Read article
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Elemental Mobility and Provenance in Sediments: A Geochemical Study of Deccan Basalts, Bay of Bengal, and Northern China
Abstract: Twenty-eight sediment samples from seventeen rivers, including the Krishna headwaters and the west-flowing Western Ghat rivers, draining the Deccan Trap basalts, were analyzed for major elements (Na, Ca, Mg, K, Al, Ti, Fe) and trace elements (Sr, Ba, Mn, P, V, Cr, Ni, Cu, and Zn). The mobility of these elements, especially Na, Ca, Mg, and Sr, was assessed by comparing their abundances in sediments and dissolved phases. Approximately 60% …
Published in International Journal of Minerals · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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Beryllium Mineralogy and Its Strategic Applications in Modern Industries
Abstract: Beryllium, a rare lithophile element, exhibits unique physical and chemical properties that make it indispensable in various high-technology industries, including aerospace, nuclear energy, defense, and telecommunications. This review explores the mineralogy, extraction, applications, and resource distribution of beryllium, highlighting the metallurgical and industrial significance of its primary minerals, beryl and bertrandite. Despite being one of the lightest metals, beryllium boasts high strength, heat resistance, and conductivity, properties that support its …
Published in International Journal of Minerals · Vol. 1, Issue 2, 2024 · pp. 28–33 Read article
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The Impact of Climate Change on Jute Production in Gaibandha District, Bangladesh
Abstract: Jute plays a crucial role in Bangladesh’s agricultural economy, especially in Gaibandha District, where it is a key crop for rural livelihoods. However, climate change, characterized by rising temperatures and unpredictable rainfall, poses significant threats to jute production. While numerous studies have explored the broader impact of climate change on agriculture, there is a gap in understanding how localized climate conditions specifically affect jute farming in Gaibandha, with many existing …
Published in International Journal of Climate Conditions · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Self-Healing Thin Films: Paving the Way for Smart, and Sustainable Corrosion Protection
Abstract: Corrosion is one of the serious problems that industries and infrastructures of every type face, ranked among such threats as huge economic losses and concerns to global safety. Recent developments in the area of self-healing thin films make them a really promising innovation for enhancing corrosion protection. This review considers the development, mechanisms, and applications of self-healing thin films. Detailed here are intrinsic and extrinsic self-healing strategies oriented toward chemical …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 22–45 Read article