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833 articles for “Resistance”
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The Interplay Between Hyperglycemia, Endothelial Dysfunction, and Cardiovascular Risk in the Context of COVID-19: Implications for Long-term Health
Abstract: The COVID-19 pandemic has highlighted the potential impact of hyperglycemia, especially its link to cardiovascular disease (CVD) and endothelial dysfunction. COVID-19 can cause systemic inflammation and endothelial damage, worsening complications related to hyperglycemia. Persistent inflammation and endothelial dysfunction are crucial elements in the progression of atherosclerosis and other cardiovascular diseases. The long-term health effects of COVID-19, known as “Long COVID” or post-acute sequelae of SARS-CoV-2 infection (PASC), have raised concerns …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 27–31 Read article
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Whispers of the Microbial World: Unveiling Bacterial Dialogues through Quorum Sensing
Abstract: Quorum sensing is a special way of bacteria by which they can regulate their own gene expression as per the population density of the bacteria. It is basically a type of cell-to-cell communication pathway used by the microbes. The signal molecule which helps in this mechanism are called auto inducer(AI). As the mechanism depends by changes in the cell density, so when the cell density reaches to the threshold cell …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Comparison Study of Non-Alcoholic Sanitizer and Alcohol Based Sanitizer
Abstract: Hand sanitizer is the best choice to maintain the hand hygiene and stopping the spread of infectious diseases. The active ingredient in traditional hand sanitizers is usually alcohol, but worries about flammability, skin irritation, and possible abuse have prompted the creation and growing popularity of alcohol-free substitutes. The purpose of this review is to objectively assess the safety, effectiveness, and usefulness of alcohol-free hand sanitizers. To successfully eradicate germs, alcohol-free …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Understanding Metabolic Syndrome and its Nutritional Management
Abstract: Metabolic syndrome (MetS) is a collection of risk factors, especially when at least three occur together, including abdominal obesity, dyslipidemia, low high-density lipoprotein cholesterol (HDL-c) levels, hypertension, and insulin resistance. MetS is linked to an increased risk of diabetes and cardiovascular diseases (CVDs) if treatment is not received.The causes of MetS include both genetic and acquired factors that contribute to issues such as insulin resistance, chronic low-grade inflammation, and obesity. …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 26–37 Read article
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Study of Ablation Characteristics Carbon Fiber Reinforced Plastic with Silicon Carbide Pores
Abstract: Significant thermal stress is placed on spacecraft during atmospheric re-entry, primarily due to aerodynamic heating. This intense heat can cause severe material damage threatening the spacecraft's structural integrity. To address this challenge, efforts are focused on improving the ablation resistence of spacecraft components. In this work, carbon fiber reinforced plastic (CFRP) composites containing silicon carbide (SiC) holes are explored as a potential solution for enhancing thermal protection system. Four different …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 617–627 Read article
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Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Photonic Polymer Composites for Light-Modulating Displays and High-Throughput Optical Data Transmission
Abstract: The combination of PMMA-based composites recently received substantial attention from the photonic applications field since these materials combine excellent optical transparency, mechanical flexibility and straightforward fabrication capabilities. The material performance of pure PMMA requires functional additives because it shows limited thermal properties and optical attenuation in addition to sensitivity against UV rays. The research explores developmental pathways for PMMA composites through combined use of nanoparticles and electro-optic polymers with dopants …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 838–860 Read article
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Optimization of Lightweight Polymer Composites Using Finite Element Analysis Machine Learning and Topology Optimization Techniques for Aerospace Applications
Abstract: The advancement of aerospace engineering depends on lightweight polymer matrix composites (PMCs) because they help decrease weight while improving fuel efficiency and payload capacity together with increased structural integrity. Research developed a computer program comprising FEA with ANN and TO optimize high-performance PMCs through integrated design approaches. The combination of Python-controlled LS-DYNA simulations measured hybrid composite laminate resistance to impact while an ANN model obtained data from simulations to forecast …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 693–709 Read article
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Innovative Polymer Nanocomposites: Bridging Sustainability and Advanced Material Performance
Abstract: This study examines the evolution of bio-based polymer nanocomposites using eco-friendly synthesis methods to improve mechanical, thermal, and barrier properties. It involves the combination of sustainable synthetic polymers with natural polymers in the presence of nanofillers in a green and compatible fashion to generate durable nanocomposites. Optimal alignment of nanofillers with the polymer matrices can be achieved using solvent casting, melt blending, and in-situ polymerization as fabrication methods. Consequently, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1671–1679 Read article
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Redefining Herd Health: No-Antibiotic Strategies for Revolutionizing Sustainable Dairy Development
Abstract: This study investigates the potential of no-antibiotic strategies to transform herd health management andpromote sustainable dairy development. Rising concerns over antimicrobial resistance (AMR) and the environmental consequences of antibiotic use have intensified the demand for alternative, sustainable disease management approaches. No-antibiotic strategies emphasize preventive health measures, biosecurity, and holistic practices, including optimized nutrition, vaccination, and natural antimicrobial alternatives. The study evaluates diverse management interventions, such as precision livestock farming, genetic …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Wear and Tribological Characteristics of Novel Metal Matrix Composites
Abstract: The development of advanced metal matrix composites (MMCs) with enhanced tribological performance has become increasingly important due to the premature failure of critical engineering components operating under severe wear conditions in automotive, aerospace, marine, defense, and power generation systems. Conventional composites such as Copper–Alumina and Aluminium–Silicon Carbide have demonstrated improved mechanical and wear characteristics; however, their widespread application is often limited by issues including particle agglomeration, non-uniform reinforcement distribution, porosity …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1326–1346 Read article
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Investigation on bi-layer knitted fabric produced using recycled polyester and banana fiber for improved moisture and thermal comfort properties
Abstract: This research investigates thermal comfort characteristics of bi-layer knitted fabrics made of banana fibers and recycled polyester (rPET). The main aim is to maximize thermal comfort of textile products by taking advantage of the distinctive characteristics of these two varieties of eco-friendly materials. Recycled polyester and banana fibers were combined to make the bi-layer knitted materials, which is produced as separate inner and outer layers to maximize performance. The features …
Published in Journal of Polymer & Composites Read article
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Investigation on bi-layer knitted fabric produced using recycled polyester and banana fiber for improved moisture and thermal comfort properties
Abstract: This research investigates thermal comfort characteristics of bi-layer knitted fabrics made of banana fibers and recycled polyester (rPET). The main aim is to maximize thermal comfort of textile products by taking advantage of the distinctive characteristics of these two varieties of eco-friendly materials. Recycled polyester and banana fibers were combined to make the bi-layer knitted materials, which is produced as separate inner and outer layers to maximize performance. The features …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 19–24 Read article
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Improvements in Analog Performance of Dual Metal Gate based Silicon-on-Insulator Junctionless Transistor with Pocket Doped Window
Abstract: This paper elucidates the impact of the pocket doped window on the analog performance of dual metal gate based silicon-on-insulator junctionless transistor (DMG SOIJLT). The analog parameters of the proposed SOIJLT are compared with DMG based conventional SOIJLT. The findings of analog performance comparison reveal that transconductance (gm), transconductance generation factor (TGF), output conductance (gd), output resistance (r0), intrinsic gain (AV), and cut-off frequency (fT) have improved for DMG PD-SOIJLT …
Published in Journal of Microelectronics and Solid State Devices Read article
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Antibiotics – Challenges in our Post-COVID Era
Abstract: Accidental discovery of the antibiotic properties of penicillin marked a watershed moment in healthcare, transforming the landscape of medicine and saving countless lives of injured and infected. Further research and awareness on the advantages of this “miracle drug” resulted in its bulk production in the 1940s, and played a crucial role in saving lives of thousands during World War II. Subsequent discoveries especially broad-spectrum antibiotics paved the way for further …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 1–5 Read article
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Geopolymer Concrete with Cenosphere as Fine Aggregate: A Material Characterisation
Abstract: Geopolymer concrete (GPC) is regarded as the successor to traditional concrete as it eliminates the requirement for conventional Portland cement during its manufacturing process, hence decreasing CO2 emissions. This study employed Cenosphere, which are lightweight fine materials, to partially substitute the volume of sand in GPC. Cenosphere was utilized in proportions of 20%, 40%, 60%, and 100%. This experiment examined the fresh and hardened characteristics, durability against freezing and thawing, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 143–151 Read article