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395 articles for “Promising approach”
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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Overcoming Obstacles to an HIV-1 Cure: Advances in Genome Editing, Immune System Reprogramming, and Viral Reservoir Elimination
Abstract: Human immunodeficiency virus type-1 (HIV-1) continues to represent a major global health challenge despite the remarkable success of antiretroviral therapy (ART). Although ART effectively suppresses viral replication and prolongs survival, it cannot eradicate the virus due to the persistence of long-lived latent reservoirs. In recent years, innovative therapeutic strategies have been explored with the aim of achieving either a functional remission or complete viral elimination. Advances in genome-editing technologies, particularly …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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AI-Based Preventive Healthcare Using Quantum Computing
Abstract: With its improved performance and capabilities, quantum machine learning (QML) is becoming a promising field, especially in the healthcare industry for tasks like early heart disease prediction. In this work, a Quantum Support Vector Classifier (QSVC) is proposed as the basic classifier for a bagging ensemble learning model. Shapley Additive explanations (SHAP) are used to evaluate the significance of each attribute in the predictions in order to improve explainability. Using …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 Read article
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Nanotechnology and Nanoparticles for High Altitude Agro-ecosystem and Environmental Sustainability
Abstract: High-altitude agro-ecosystems are widely distributed throughout the world. In the Indian subcontinent, Himalayan region represents the high-altitude ecosystems, which demand extensive management due to their increasing deterioration in recent times. The extremely low temperature, proneness to natural calamities, recurring floods, droughts, low soil moisture and fertility, high solar intensity impose constraints for sustenance of hill agriculture. To enhance crop productivity to sustain increasing population, hill farmers are using excessive amount …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 155–164 Read article
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Managing Blow-by in Modern Engines: A Comprehensive Review of Crankcase Ventilation Technologies
Abstract: Blow-by in internal combustion (IC) engines occurs when high-pressure combustion gases escape past the piston rings into the crankcase. These gases typically carry oil aerosols, unburned hydrocarbons, and fine particulate matter, which, if not effectively managed, can disrupt lubrication, accelerate component wear, and contribute to harmful emissions. Effective crankcase ventilation is therefore essential not only for ensuring engine durability but also for meeting increasingly stringent emission regulations. This paper examines …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 317–324 Read article
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Utilize Nature’s Power: Nutraceuticals in the Fight Against Dengue
Abstract: As dengue fever continues to surge across tropical and subtropical regions, the exploration of novel therapeutic approaches is crucial. Nutraceuticals, natural bioactive compounds derived from food sources, are emerging as promising adjuncts in the fight against this viral disease. Unlike conventional treatments that primarily target symptoms, nutraceuticals offer a complementary strategy by enhancing the body’s immune defense and addressing key complications. This review highlights the diverse potential of nature’s remedies, …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
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Computational Simulations in Drug Discovery: Modeling Protein Folding and Drug Binding
Abstract: Computational simulations have become essential tools in drug discovery, offering unprecedented insights into molecular behavior at the atomic level. These simulations, particularly in the domains of protein folding and drug binding, allow for the exploration of complex biological systems that are often difficult to study experimentally. Protein folding, a critical aspect of drug discovery, involves the transition of a polypeptide chain from an unfolded to a biologically active structure. Understanding …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 23–29 Read article
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Virtual Reality Graded Exposure Therapy For Phobia And Ptsd
Abstract: By combining virtual reality technology with graded exposure therapy, Virtual Reality Graded Exposure Therapy (VRGET) transforms the treatment of anxiety disorders. VRGET uses controlled exposure to anxiety-inducing stimuli using immersive virtual environments, addressing the global problem of anxiety disorders. By simulating real-world scenarios, VRGET provides a structured and immersive approach that allows individuals to gradually confront their fears in a controlled, supervised, and safe environment. Technology offers adaptable scenarios tailored …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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An Innovative Approach to Find the Optimum Lubricant for Diverse Applications Based on Scikit-Learn Library Using Python
Abstract: This paper presents an innovative approach for finding the optimum lubricant using the Scikit-learn library in Python. The proposed approach uses a linear regression model to analyze a dataset of lubricant properties and performance, specifically the viscosity, wear, and friction. The model is trained on the dataset to predict the wear and friction for a given viscosity, which can be used to identify the optimum lubricant. By analyzing a dataset …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 25–35 Read article
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Towards a Sustainable Future: A Comprehensive Study on Solar Power Satellites
Abstract: This study explores solar power satellites (SPS) as a promising solution for sustainable energy. Space-based solar power (SPS) offers a revolutionary approach to clean energy by collecting solar energy in space and transmitting it wirelessly to Earth. Unlike terrestrial solar power, SPS can operate continuously, unaffected by weather or nightfall, providing a stable and sustainable energy source. This study explores the core technologies that enable SPS, including advanced photovoltaic systems …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 1–8 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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Antimicrobial Resistance and AI-Based Strategies for Rapid Pathogen Detection
Abstract: Antimicrobial resistance (AMR) has become a major global health threat, significantly reducing the effectiveness of antimicrobial therapies and increasing the burden of infectious diseases worldwide. The rapid emergence of multidrug-resistant pathogens has created an urgent need for faster, more accurate, and scalable diagnostic approaches to support timely treatment and effective infection control. Artificial intelligence (AI) has emerged as a promising technology capable of transforming pathogen detection and AMR surveillance through …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Non -Invasive Ways to Detect Cancer
Abstract: Cancer is a diverse group of diseases characterized by uncontrolled cell growth and division, affecting millions worldwide and being a leading cause of death. The disease typically involves genetic alterations that disrupt the normal balance of cell growth, leading to the formation of tumors. Tumors can be benign, posing no threat as they do not spread, or malignant, capable of invading nearby tissues and metastasizing. There are more than 100 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 59–67 Read article
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Strategies in the Battle against Recurrent UTIs: A Brief Overview
Abstract: Recurrent urinary tract infections (UTIs) present a serious medical issue, and such conditions can disappoint those affected. They are uncomfortable, but a difficulty arises because treating such conditions with antibiotics comes with the risk of antibiotic overuse. This summary will evaluate the measures incorporated in treating frequent UTIs in the contemporary world. These measures include taking antibiotics regularly to prevent infections and alternatives to antibiotics such as probiotics, cranberry extract, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 68–73 Read article
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Green AI-Enabled Opto-Electronic Communication Systems for Carbon-Neutral Digital Networks
Abstract: The rapid expansion of digital communication infrastructure, driven by cloud computing, Internet of Things (IoT), 6G networks, and artificial intelligence applications, has significantly increased the energy consumption and carbon footprint of modern communication systems. Conventional optical communication networks often rely on static resource allocation and energy-intensive signal processing mechanisms, resulting in inefficient utilization of network resources and elevated operational costs. This study proposes a Green Artificial Intelligence (Green AI)-Enabled Opto-Electronic …
Published in Trends in Opto-electro & Optical Communication · Vol. 16, Issue 2, 2026 Read article
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Distinctive Approaches for Improving the Aqueous Solubility of BCS Class II Drugs
Abstract: The most difficult feature of many novel chemical entities is their solubility behaviour, as 60 percent of new promising products suffer solubility limitations. This is the most common reason for novel medicine compounds failing to reach the market or performing to their full potential. The proportion of the aqueous phase when the solution is in equilibrium with the pure substance in its normal phase is referred to as aqueous solubility. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 52–56 Read article
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Designing a Disaster Resilient Community in Flood prone zones of Srinagar, Uttarakhand.
Abstract: Uttarakhand, a state that scuffles with the dual challenges of climate change and rapid development, is particularly vulnerable to devastating floods. This research delves into the critical issue of strengthening community resilience against such disasters. By examining the interconnected factors of preparedness, mitigation, and response, the study aims to develop a robust framework for safeguarding lives and livelihoods in flood-prone regions. A cornerstone of this research is the exploration of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 2, 2024 · pp. 8–19 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article