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178 articles for “Phytochemical compound”
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Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation
Abstract: Inflammation and rheumatism remain serious health problems in the present era. In the present attempt, the authors developed anti-inflammatory gel which gives benefit of faster permeation for quicker action. This anti-inflammatory gel is very useful for the arthritis patients. For the formulation purpose Boswellia serrata (Shallaki) and Commiphora mukul (Guggul) were selected because very less work has been done on these plants and for synergistic effect known of herbal extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 1–8 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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Computational Investigation of Withania somnifera Compounds Targeting S. pombe SMN YG-Dimerin Spinal Muscular Atrophy: Insights from Molecular Docking Analysis
Abstract: Objectives: The primary objective of this study is to determine the potential of phytochemical constituents of Withania somnifera in treating spinal muscular atrophy, an autosomal recessive genetic neurodegenerative disorder, through computational techniques. To investigate the binding affinity of phytocompound to the target protein S. pombe SMN YG-Dimer through molecular docking. Besides, evaluating the pharmacological attributes of phytochemical constituents to assess their ability as an ideal prospect for developing therapeutic medication. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 39–52 Read article
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Nutraceutical Potential of Millets
Abstract: Millets have garnered growing interest because of their exceptional nutraceutical properties. Due to their abundant supply of vital nutrients and bioactive substances, millets show significant potential in enhancing health and reducing the risk of chronic illnesses. This paper emphasises the significant nutritional content of millets, which are devoid of gluten and abundant in protein, vitamins, and minerals, rendering them a superb dietary choice for those suffering from gluten sensitivity or …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 3, 2024 · pp. 31–37 Read article
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Preliminary Phytochemical and TLC Studies on Bacopa monnieri (L.) Pennel
Abstract: Baccopa Monnieri (Scrophulariaceae), an important medicinal plant belonging to the family Scrophulariaceae, which has been valued for centuries in Ayurvedic medicine. The study was carried out for determining Phytochemical and TLC studies of Bacopa monnieri. The different qualitative chemical test was performed on the extracts to detect the various phyto constituents present in them. The photochemical screening reveals the presence of many therapeutically important compounds such as glycosides, alkaloids, saponins, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 1, 2011 · pp. 122–125 Read article
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Investigating Curcumin Phytocompounds as Prospective Parkinson's Disease Therapeutic Agents: A Computational Method that Targets LRRK2 Protein
Abstract: Objective: Parkinson’s Disease is the second stage predominant neurodegenerative illness. Primary aetiology is still unknown. One of the biggest battlegrounds in modern medicine is discovering the cause of Parkinson’s disease (PD), as well as the hunt for palliative treatments and, if feasible, a cure. The objective of this work is to identify the phytocompounds from curcumin (curcuma longa) for the treatment of PD. Curcumin, a well-researched phytochemical, has been suggested …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 55–67 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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Application of Fruit and Vegetables Peels as Functional Ingredients in Baked Cookies: A review
Abstract: About half of the waste produced by industrial fruit and vegetable manufacture is in the form of peels, cores, pomace, and unripe or damaged fruits and vegetables. Many fruits and vegetables, including citrus, apples, peaches, pears, bananas, pomegranates, berries, mangoes, and sugar beet, have peels, pulp/pomace, and seeds that contain concentrations of phenolics and other phytochemicals that are typically much higher than in the edible tissues of those fruits and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 2, 2024 · pp. 11–19 Read article
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Amentoflavone and Mangiferin in Hypericum calycinum, Hypericum cardiophyllum and Hypericum bithynicum
Abstract: The present study was conducted out to determine amentoflavone and mangiferin contents of Hypericum calycinum, Hypericum cardiophyllum and Hypericum bithynicum, growing wild in Turkey. The aerial parts representing a total of 30 individuals were collected at full flowering, dried at room temperature and assayed for secondary metabolite concentrations by HPLC-PDA. Both compounds were detected in all three species in different amounts depending on plant tissue. Results were discussed in phytochemical …
Published in Research & Reviews : Journal of Herbal Science · Vol. 6, Issue 1, 2017 · pp. 10–13 Read article
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Preliminary Phytochemical and Acute Toxicity Studies of Different Extracts of Guiera Senegalensis
Abstract: The leaf of Guiera senegalensis is used in the management of many diseases in Nigeria and many African countries, but the medial lethal doses (LD50) of its different extracts are not widely investigated. To evaluate the phytochemical constituents and acute toxicity indexes of aqueous, hexane, dichloromethane and methanol leaf extracts of G. senegalensis, basic phytochemical screening methods were applied. While up and down procedure and Lorke’s method was used for …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 3, 2019 · pp. 11–16 Read article
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Computational Screening of Vitex negundo Compounds for Potential Arthritis Therapies in India
Abstract: Objective: Arthritis is a pervasive medical condition that manifests as inflammation and discomfort within the joints. As of September 2021, arthritis has affected an estimated 180 million people in India, making it a substantial public health concern with a considerable impact on individuals' quality of life and healthcare systems. Therefore, using molecular docking, drug-likeness prediction, and ADME analysis, an effort was made to identify natural compounds from Vitex negundo, which …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 01–18 Read article
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Biosynthesis of Silver Nanoparticles using Leaf and Stem Extracts of Eclipta alba and their Medical Applications
Abstract: AbstractBiosynthesis of silver nanoparticles using plants has emerged as a simple and feasible alternative to more complex physical and chemical synthetic procedures. Nanoparticles synthesis through greener routes can be used in a safer mode for various human applications. In this work, we describe a cost effective and environment friendly technique for biosynthesis of silver nanoparticles from 1mM AgNO3 solution using leaf and stem extracts of Eclipta alba as reducing as …
Published in Research & Reviews : Journal of Botany · Vol. 2, Issue 1, 2013 · pp. 1–9 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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To Estimate the Antibacterial Activity of Piper Nigrum Extract
Abstract: A natural remedy called piper nigrum is used to cure a variety of illnesses. It is employed in conventional herbal medicine for a number of therapeutic applications. Alkaloids, tannins, phenolics, and other phytochemicals can be found in Piper nigrum leaf tissue. In different places, medicinal plants are employed as a source of several effective and strong medications and are a rich supply of antibacterial compounds. The main chemical component that …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 2, 2023 · pp. 62–74 Read article
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Phytochemical, Pharmacological and Toxicological Studies of Solanum americanum: A Systemic Review
Abstract: Solanum americanum, a plant widely used in folk medicine, has recently gained attention in the scientific community due to its diverse therapeutic potential. The bioactive compounds found in different plant parts, such as alkaloids, flavonoids, and tannins, have significant medicinal effects. These compounds exhibit several pharmacological properties, such as antimicrobial, anti-inflammatory, anticancer, and antioxidant effects. However, despite these medicinal benefits, some compounds show significant toxicity to the human body if …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 2, 2025 · pp. 52–62 Read article
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Phytochemicals And Antioxidants Properties of Zanthoxylum zanthoxyloides Root Bark
Abstract: There have been studies on Zanthoxylum zanthoxyloides (Orinata), family; Rutaceae, which has shown remarkable benefits of the plant to humans traditional medicine. Root or stem bark macerations, decoctions or infusions of the plant are widely taken to treat malaria, fever, sickle cell anemia, tuberculosis, paralysis, oedema and general body weakness. They are also widely taken to treat intestinal problems, including colic, dysentery, intestinal worms, gonorrhea and urethritis. Studies show that …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 2, 2022 · pp. 23–28 Read article
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Molecular Docking Studies of Nyctanthes arbor-tristis Phytochemicals for Targeting TNF Receptor in Arthritis
Abstract: Rheumatoid Arthritis is an autoimmune disorder which results in inflammation. Tumor necrosis factor-alpha (TNF-α) is responsible for the progression of inflammatory arthritis by promoting immune cell activation and cytokine release. The present study explores the potential of bioactive compounds derived from Nyctanthes arbor-tristis (Parijat) in modulating TNF receptor activity through molecular docking. Computational methods were employed to evaluate the binding affinity of selected phytocompounds from N. arbor-tristis against the extracellular …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 11–21 Read article
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Evaluation of Chemical Constituents of Terminalia Arjuna Bark: As a Cardio-Protective Agent
Abstract: In the past, the primary source of medicinal agents was herbal remedies. One such medicinal plant that is well known for its many therapeutic benefits, particularly its cardiovascular effects, is Terminalia arjuna (TA). The therapeutic effects of these substances are due to a wide range of natural chemical compounds, such as flavonoids, polyphenols, triterpenoids, tannins, glycosides, minerals, proteins, and others. These compounds work together to provide the health benefits associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 1–6 Read article