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156 articles for “Mechanisms of Action”
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Model to Predict a Ratio Control of Hydrocarbon Acid and Water in a Packed Bed Reactor
Abstract: Model development was carried out to examine the ratio of hydrochloric acid gas and water in a packed bed reactor. The research predicted increase in output with increase in time, revealing the effectiveness ratio control of hydrochloric acid separation from water using absorption column mechanism. The density of the products played an active role in the separation process as well as in control action function. The developed model can be …
Published in Emerging Trends in Chemical Engineering Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Developing a Comprehensive Framework for User and Entity Behavior Analytics (UEBA): Integrating Advanced Machine Learning and Contextual Insights
Abstract: User and Entity Behavior Analytics (UEBA) has emerged as a crucial approach in modern cybersecurity for detecting and mitigating insider threats, compromised accounts, and other malicious activities within organizational networks. However, existing UEBA frameworks often face challenges in scalability, detection accuracy, and response effectiveness. This research work proposes a novel framework for UEBA that aims to address these limitations and enhance threat detection and response capabilities. The framework integrates advanced …
Published in Journal of Communication Engineering & Systems · Vol. 14, Issue 2, 2024 · pp. 20–32 Read article
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ML-Enhanced Self-Healing Fiber-Reinforced Polymer Composites with Embedded IoT Sensors for Damage Prediction
Abstract: Fiber-reinforced polymer (FRP) composites are widely used in aerospace and structural systems; nevertheless, the potential for microcracking and fatigue-induced performance degradation remains an obstacle with respect to improved service life. Traditional self-healing methods, while performing well on a chemical level, often lack real-time diagnostic awareness and adaptive control. To circumvent this, we developed a machine-learning augmented self-healing FRP composite, in which a DCPD–Grubbs catalytic matrix was combined with IoT sensor …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 188–208 Read article
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Performance Forecasting in Solo Sports: Leveraging Psychometrics, Economic Analysis, and Cultural Insights for Predictive Excellence
Abstract: The science of performance forecasting in solo sports has transcended traditional metrics, embracing a multidisciplinary approach. This paper explores the integration of psychometrics, economic analysis, and cultural insights to predict athletic success. By leveraging psychological profiling, economic factors, and cultural dynamics, this study aims to establish a comprehensive model for forecasting athlete performance with heightened accuracy. In the realm of solo sports, where individual prowess dictates success, traditional performance forecasting …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 35–44 Read article
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Enhancing Surface Roughness of Polylactic Acid (PLA) 3D-Printed Parts Using CO₂ Laser Scanning: An Experimental Study on Parameter Optimization
Abstract: Fused deposition modeling (FDM) of polylactic acid (PLA) often suffers from poor surface finish due to the inherent layer-by-layer deposition process, limiting its use in high-precision applications. This study investigates CO₂ laser scanning as an efficient post-processing technique to reduce the surface roughness (Ra) of PLA parts while maintaining structural integrity. Specimens (100 × 80 × 5 mm) were fabricated with varying infill densities (35%, 70%, and 100%) to assess …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 503–511 Read article
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Combining Unstructured and Structured Clinical Data in a Hybrid Transformer Model to Enhance Cardiovascular Analytics and Clinical Decision- Making
Abstract: Since cardiovascular disease (CVD) continues to be a major global cause of morbidity and mortality, early and accurate risk prediction is essential for prompt intervention and individualized treatment. This study introduces a new hybrid transformer-based model that combines unstructured clinical narratives, structured data, and customized lifestyle characteristics. A comprehensive understanding of disease progression is made possible by the model's ability to capture contextual, temporal, and patient- specific insights through the …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 · pp. 30–37 Read article
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Exploring the Synergy of High Performance Composite Concrete Strength and Sustainable Construction Practice
Abstract: This research evaluates how the combination of industrial waste materials optimizes composite concrete structure strength and services the interests of sustainable construction development. This research examines two major environmental problems stemming from ordinary Portland cement clinker manufacturing and landfill accumulation of non-biodegradable porcelain waste. The research employed alccofine dosage of 16% as a supplementary cementitious material (SCM) with high pozzolanic activity to combat these problems. Processed porcelain waste aggregates filled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 47–58 Read article
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Study on the Response of Strengthening Strategies for Masonry-infilled Open Ground Storey Framed Building
Abstract: The strengthening of reinforced concrete (RC) frame buildings with masonry infill wall and with open ground storey is a very timely and significant topic because of the poor performance against seismic action. The absence of infill walls in the ground storey makes the ground storey less stiff and weaker than the all upper storys which results in a poor performance against lateral loads. Soft storey mechanism prevails in these cases …
Published in Journal of Structural Engineering and Management Read article
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Automatic Gas Leakage Detection System
Abstract: This project report presents the design and implementation of a focused automatic gas leakage detection and ventilation system centered on the Arduino Nano microcontroller and the MQ-2 gas sensor. The primary function of the system is to detect flammable gases like LPG, propane, and methane using the MQ-2 gas sensor. This sensor continuously monitors the surrounding air for the presence of these gases. When the gas concentration crosses a predefined …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 3, 2025 · pp. 29–35 Read article
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Medicinal Potential of Cullen corylifolium in Ageing and Ageing Related Diseases
Abstract: Cullen corylifolium is a tropical medicinal plant of the Fabaceae family, generally known as Babchi/Bakuchi in various regions of Asia. Cullen corylifolium is a traditional phyto-therapeutic plant of China used to manifest various pathological conditions since ages, possesing round and dark brown seeds with a rough texture. Cullen corylifolium has been previously reported to possess various properties such as antioxidant, anti-inflammatory and can be used as a solution to treat …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article
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Application-Driven Rule-Based Framework for Lubrication Failure Modes in Industrial Systems
Abstract: Modern lubricants increasingly rely on polymer-based composites, integrating synthetic base oils, polymer thickeners and solid additives like MoS₂ and PTFE for high-performance applications. These formulations not only enhance thermal and mechanical stability but also enable low-friction operation across diverse industrial conditions. Lubrication-related failures represent a critical cause of unplanned downtime and reduced reliability in industrial machinery. This paper presents an application-driven, rule-based framework designed to assess and mitigate lubrication failure …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 522–531 Read article
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Climate-Induced Infertility in Dairy Cows: Pathways, Challenges, and Solutions for Sustainable Dairy Development
Abstract: Climate change has emerged as a significant challenge to dairy production, with profound implications for reproductive performance in dairy cows. The interplay of rising temperatures, fluctuating rainfall patterns, and increased frequency of extreme weather events disrupts key physiological, nutritional, and behavioral processes essential for fertility. Heat stress alters hormonal balance, impairs oocyte and embryo quality, reduces estrus expression, and affects pregnancy outcomes. Concurrently, climate-induced nutritional deficits, immune suppression, and increased …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 Read article
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Biodegradable Polymer Nano Composites for Enhanced Drug Bioavailability
Abstract: Polymer-based nanoparticles have emerged as a revolutionary approach in drug delivery systems, particularly in enhancing the bioavailability of poorly soluble and unstable drugs. These nanoparticles, composed of both natural and synthetic polymers, serve as effective vehicles for encapsulating a wide range of therapeutic agents. Their surface characteristics can also be modified to enable targeted drug delivery, increasing the concentration of drugs at the site of action while minimizing side effects. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 433–443 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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An Automated Smart Contract Repair Framework for Reentrancy, Integer Overflow, and Denial- of-Service Vulnerabilities
Abstract: This paper introduces a novel static analysis framework designed to bridge a long-standing gap in Ethereum smart contract security: the disconnect between vulnerability detection and automated remediation. Although widely adopted tools such as Slither and Oyente are highly effective at identifying security weaknesses, they stop short of providing actionable fixes. As a result, developers manually patch vulnerabilities, a process that is not only time-consuming but also susceptible to human error …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 31–41 Read article
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Understanding Food Spoilage: Mechanisms, Shelf-Life Determination, and Safety Standards
Abstract: Food spoilage poses significant challenges to the global food industry, impacting both food safety and economic sustainability. The main causes of food quality deterioration are microbial and non-microbial spoiling. Microbial spoilage primarily results from the activity of bacteria, yeasts, and molds, which thrive under favorable environmental conditions. These microorganisms can lead to food poisoning and spoilage through the production of off-flavors, discoloration, slime formation, and the accumulation of harmful toxins. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 6–9 Read article
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Polysaccharide-Based Hydrogels for Sustained Drug Release in Pharmacology
Abstract: Polysaccharide-based hydrogels have showed great potential in medicine as materials for long-lasting, under control medication delivery systems. Natural polysaccharides include chitosan; alginate, agarose, and cellulose form these hydrogels. Among its many advantages are biocompatibility, biodegradability, and customising ability for various drug release rates. Reacting to pH, temperature, and ionic strength changes in the surroundings, polysaccharide-based hydrogels may swell. For usage requiring the release of therapeutic substances over an extended period …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 300–312 Read article
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Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
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Modelling of Wind-Wave Misalignment for Floating Offshore Wind Turbines
Abstract: The influence of the combined effects of wind and waves onto the performance of a floating offshore wind turbine (FOWT) is analyzed. A study of the wind conditions relative to the position of the aerodynamic rotor has been made, analyzing how the angle of incidence of the wind (angle of attack) varies with the wind direction and the inclination of the wind turbine mast as a consequence of the undulatory …
Published in Journal of Offshore Structure and Technology Read article