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116 articles for “Anti-viral”
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Prevalence of Mucocutaneous Manifestation and Associated Factors Among Adult HIV Positive Patients Attending Art Clinic in Mekelle Zonal Hospital
Abstract: Mucocutaneous disorders are among the first recognized clinical manifestation of HIV/AIDS and they help as a visual marker in assessing the progression of HIV/AIDS. More than 90% of HIV-positive patients may develop mucocutaneous problems at one stage of the disease or the other with significant morbidity and mortality and the magnitude of mucocutaneous manifestation is not known in Mekelle. The objective of this study was to determine the magnitude and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 2, 2015 · pp. 21–30 Read article
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TORCH Profile: A Convenient Method for Screening Infection in Pregnancy by ELISA: A Review
Abstract: TORCH is a medical acronym for a set of perinatal infections: toxoplasmosis, other (syphilis), rubella (German measles), cytomegalovirus (CMV), herpes simplex virus (HSV-1, 2). They are a group of viral, bacterial and protozoan infections that gain access to the fetal bloodstream transplacentally via the chorionic villi or hematogenous transmission any time during gestation or occasionally at the time of delivery via maternal-to-fetal transfusion. TORCH infections may result in abortion, still …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 16–21 Read article
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A Comprehensive Review on Monkeypox Infection
Abstract: Monkeypox represents a zoonotic viral affliction instigated by the monkeypox virus, which is classified within the Poxviridae family and is distinct from the virus that causes chickenpox. Initially recognized in 1958, this infection has recently attracted international scrutiny due to its escalating incidence beyond traditional endemic territories. This review delivers an exhaustive examination of monkeypox, encompassing its epidemiology, viral morphology, modes of transmission, pathogenesis, clinical presentations, and therapeutic interventions. The …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 23–32 Read article
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The Review on Efficacy of Ozone Therapy in the Treatment of COVID 19
Abstract: The Corona Virus Disease 2019 (COVID 19) has created a global pandemic with a significant mortality and morbidity rate. Presently, with no vaccine or standard therapy available, the healthcare system has turned to correlate the existing therapies with the disease pathology and viral structure of corona virus. So thereby revisiting the existing therapies, here one of the highly efficient, safe and inexpensive ozone therapies. A multitude of ozone therapies have …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 7–11 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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A brief review on Influenza A virus (H 3 N 2 ) and its effects in human with precondition
Abstract: A primary cause of human influenza is the viral genus Influenzavirus A, of which H3N2 is a subtype. The virus has undergone various mutations, resulting in the emergence of different strains, affecting pigs, humans, and birds. H3N2 exchanges internal protein-coding genes with other influenza subtypes through reassortment. The H3N2 virus, which is a type of seasonal influenza A virus, is still circulating globally and is causing symptoms very similar to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 1, 2023 · pp. 13–17 Read article
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Potentiality of Bacteriocins as the Attachment Inhibitors of HIV-1 gp120
Abstract: It is postulated that some bacteriocin derivatives are consummate candidates to inhibit the binding of HIV gp120 to CD4 T-cell. From the discovery of bacteriocin compounds in 1925 and forth, nearly 300 bacteriocins have been identified. Of various bacteriocins, there are some which have been used successfully for inhibiting both animal and human pathogens. Unfortunately, no large extent research has been found in the development of various bacteriocins as HIV …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 3, 2015 · pp. 18–23 Read article
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CRISPR, Recombinant DNA, and LAMP-Based Platforms for Monkeypox: Emerging Tools for Diagnosis and Therapeutic Development
Abstract: Monkeypox, a zoonotic viral infection caused by the Monkeypox virus of the Orthopoxvirus genus, has recurred as a worldwide public health concern after recent outbreaks outside of its classical endemic areas in Central and West Africa. The resurgence has demanded a thorough reassessment of its epidemiology, mode of transmission, and clinical presentation. In light of these challenges, recombinant DNA technology (rDNA) has emerged as a candidate for developing vaccines, diagnostics, …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 7–28 Read article
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The Outbreak of Pandemic Novel Coronavirus (COVID-19): An Overview
Abstract: Recent deadly Coronavirus (COVID-19) outbreak in Wuhan- China is not new virus. Such type of viral diseases have been found in the history like in 1967-MARBUG (virus) in Ugandan, in 1979-EBOLA (virus), 1999-NIPPAH (virus) in Malaysia, SARS-2002 in China, MERS-2012 in Saudi Arabia and other related in outbreak happened in the past. Scientists believes that the Virus have been originated from Bats. The new Coronavirus (COVID-19), outbreak has become a …
Published in Research & Reviews : Journal of Statistics · Vol. 9, Issue 2, 2020 · pp. 1–8 Read article
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Horizons in Neuralgia Care: Addressing Unmet Needs and Future Prospects
Abstract: Neuralgia refers to intense, sharp, and often chronic pain resulting from damage or irritation to nerves. It is typically characterized by sudden, shooting pain along the course of a nerve, significantly impairing daily functioning and impacting both physical and emotional well-being. Given its intensity and chronic nature, neuralgia presents a complex challenge in clinical management, emphasizing the importance of timely diagnosis and effective intervention to improve patient outcomes. This comprehensive …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Importance of Immunological Aspects in the Treatment and Vaccine Development of COVID-19
Abstract: COVID-19, a coronavirus disease spread by SARS-COV-2 virus is a highly contagious disease which leads to severe acute respiratory syndrome. It has highly jeopardized the whole globe in a pandemic situation. This disease originated from Wuhan, China in December 2019. The outbreak of this virally spread disease was very rapid and it also appeared to be life threatening. This article lays out a brief overview about the virus, its mechanism, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 3, 2021 · pp. 20–32 Read article
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Diagnosis of Dengue by NS1 Detection: Comparison of Rapid Immunochromatography versus ELISA Kits
Abstract: Dengue is an acute infectious disease of viral etiology. It is probably one of the most important arthropod borne viral disease in terms of human morbidity and mortality. The spectrum of disease ranges from self-limited dengue fever to more severe forms of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). So, to reduce mortality and morbidity early and accurate diagnosis of dengue is essential. Study assessed comparison of currently …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 18–22 Read article
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Update on Epidemiology, Virion Structure, Pathogenesis, Diagnosis, Treatment of COVID-19 with Future Perspectives: A Narrative Review
Abstract: COVID-19 or coronavirus disease 2019 is a pandemic contagion, leading to the death of many more people globally. In simpler terms, COVID-19 is a very contagious illness caused by the SARS-CoV-2 virus, which stands for severe acute respiratory syndrome coronavirus-2. The main aim of the present paper was to give an update about the incidence, mode of spread, viral multiplication, treatments available, complications with future expectations. The virus's ability to …
Published in Research and Reviews : A Journal of Immunology · Vol. 13, Issue 1, 2023 · pp. 32–47 Read article
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Efficacy of Rapid Diagnostic Tests in Relation to ELISA in Hepatitis B and C Infection
Abstract: Background: Hepatitis B surface antigen and Hepatitis C antibodies in circulation are the common markers used for diagnosis of Hepatitis B and C infection. Though ELISA is the gold standard for detection of these markers, rapid diagnostic tests like immunochromatography is used in most of the centers for quick screening of cases. This study is undertaken to compare the result of both methods. Method: Both ICT and ELISA test were …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 2, 2020 · pp. 8–13 Read article
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Inhibition of Replication of T2 Bacteriophage in Escherichia coli by 6-diazo-5-oxo-L-norleucine (DON)
Abstract: 800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 The antibiotic known as 6-diazo-5-oxo-L-norleucine, DON, inhibits the growth of several types of Gram positive and Gram negative bacteria. It has also been demonstrated that DON inhibits the replication of poliovirus, respiratory syncytial virus, mumps and herpes simplex virus in cultured eukaryotic cells. At a concentration of 0.03 mM DON, the replication of Escherichia coli cells was inhibited by 11.0% …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 2, Issue 1, 2012 · pp. 9–19 Read article