Importance of Immunological Aspects in the Treatment and Vaccine Development of COVID-19

Preyash Patel; Khushi patel; Alkesh patel

Abstract

COVID-19, a coronavirus disease spread by SARS-COV-2 virus is a highly contagious disease which leads to severe acute respiratory syndrome. It has highly jeopardized the whole globe in a pandemic situation. This disease originated from Wuhan, China in December 2019. The outbreak of this virally spread disease was very rapid and it also appeared to be life threatening. This article lays out a brief overview about the virus, its mechanism, role of immune organs and the targets by which virus can be irradicated. The article also acknowledges the current treatments available for the prevention of the disease, along with the role of herd immunity and the strategies for vaccine development in addition with the available vaccines against COVID-19 and the post COVID complications. Altogether, this article will assist in improving the understanding of the current scenario and the available vaccines against the virus. Till date, there is no specific therapy available to prevent or treat COVID-19 rather than vaccines, indeed potential medicinal moiety that may block the virus progression at various steps during infection along with helping to strengthen the antiviral immune defence of the host, reducing the situation of cytokine storm, control the oxidative stress due to comorbidity and prevent the chances of recurrence is urgent need of today’s time.

Abstract

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