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1969 articles for “quantum mechanics/molecular mechanics (QM/MM)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Resolving International Sports Disputes: An Exploration of Mediation and Conciliation
Abstract: The globalization of sports has led to an increase in cross-border disputes, necessitating effective and efficient dispute resolution mechanisms. Traditional litigation and arbitration methods often prove time-consuming, costly, and ineffective in preserving relationships. This research explores the role of Alternative Dispute Resolution (ADR) methods, specifically mediation and conciliation, in resolving international sports disputes. Through a comparative analysis of international sports organizations and dispute resolution mechanisms, this study examines the benefits …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 14–27 Read article
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Real-time Operating Systems in the Era of IoT: Challenges and Solutions for Time-Critical Applications
Abstract: Real-time operating systems (RTOS) are essential in the Internet of Things (IoT), as they ensure timely responses to events, which is critical for the performance and reliability of connected devices. This paper delves into the unique challenges faced by RTOS in IoT environments, highlighting issues such as limited computational resources, strict latency requirements, and the increasing need for robust security mechanisms. The resource constraints inherent in many IoT devices, which …
Published in Journal of Operating Systems Development & Trends · Vol. 11, Issue 3, 2024 · pp. 13–24 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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In Silico Analysis and Docking Study of the Active Phytocompounds of Bacopa monnieri Against Alzheimer Disease
Abstract: Objective: Alzheimer’s is a neurodegenerative disease and is the cause of 60–70% of cases of dementia. It infected a million people worldwide. An effort was undertaken to explore the potential of natural compounds found in Bacopa monnieri, a plant renowned for its extensive medicinal properties in Indian Ayurveda, to combat the disease. This was achieved through molecular docking studies, evaluation of drug-likeness, and comprehensive ADME (absorption, distribution, metabolism, and excretion) …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 1–13 Read article
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Cyberattack Detection and Prevention Using Empowering AI Tools
Abstract: With more organizations entering the digital transformation sphere, the opportunities and risks in cyberspace have increased and gone up in levels of sophistication and occurrence. Many of these developments are attributed to the limits of existing cyber security solutions where addressing new threats requires advanced detection technologies and techniques. Cyber threats gained a new meaning and dimension with artificial intelligence (AI) coming into play in ways that supplement security systems …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Super Ni 718 Machinability Investigation on Electrical Discharge Machining Using Hybrid Al 7(075+178) Electrode Under Abrasive Assisted Dielectric
Abstract: As aluminum alloy is the lightest metal and has the best mechanical qualities among metal, it has proven to be a perfect choice for strututal industry, particularly in the aerospace sector.7xxx alloys from the Al alloy family are widely used in aviation constructions due to their outstanding processing, welding efficiency, great specific strength & stiffness, and high toughness. The two aluminum alloys that are most frequently used in airplane structures …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1–17 Read article
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Foundation in Weak Soil
Abstract: In geotechnical engineering, it is crucial to evaluate the interaction between structural loads and soil properties to ensure the stability and safety of foundations. In this scenario, the column is subjected to a load of 120 tons, with an additional 10% safety factor added, resulting in a total load of 132 tons at the foundation base. The foundation base is designed with dimensions of 2.5 meters by 2.5 meters, and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 47–52 Read article
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Approach to Examine the Effect of Atomic Number on Single – Electron System of Group III Elements
Abstract: This study investigates the ionization energy, kinetic energy, and mass relationships among Group III elements (Boron, Aluminum, Gallium, Indium, and Thallium) to provide a comprehensive understanding of their atomic and physical properties. A detailed analysis of ionization energy trends reveals that Boron exhibits the highest ionization energy, while Thallium has the lowest, consistent with periodic trends influenced by increasing atomic radius and electron shielding. Gallium deviates slightly from this trend …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 01–09 Read article
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Innovative Porcelain Insulators: Prolonged Durability and Anti-Contamination Efficiency via Nano-TiO2 Photocatalyst Integration
Abstract: Porcelain has long been a critical material in high-voltage electrical insulation due to its exceptional mechanical, thermal, and dielectric properties. However, environmental contamination and material degradation over time pose significant challenges to its durability. This study investigates the integration of nano-sized titanium dioxide (TiO2) photocatalyst coatings on porcelain insulators to enhance their performance and prolong their operational lifespan. Local clay compositions were analyzed, and a comparative study of untreated and …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 18–23 Read article
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Biochemical Changes in Chickpea (Cicer arietinum L.) Plants Induced by Flooding
Abstract: Flooding is a significant environmental stressor that affects the growth, development, and productivity of chickpea (Cicer arietinum L.), a crucial pulse crop grown worldwide, especially in India. This study investigates the biochemical changes in chickpea plants subjected to prolonged and sudden flooding. Key parameters analyzed include carbohydrate metabolism, protein content, chlorophyll levels, amylase activity, and proline accumulation. Results show that flooding significantly reduces total sugar content in leaves, stems, and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–9 Read article
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Effect of Nano-Prepared N. sativa Seed Extract on Cardiac Tissue Structure in Tartrazine-Treated Male Albino Mice
Abstract: This study investigates the effects of Tartrazine and N. sativa nanoparticles on body weight and cardiac histology in male albino mice. Thirty-six male mice were divided into four groups: a control group receiving physiological saline, a group treated with Tartrazine (20 mg/kg), a group receiving both Tartrazine and N. sativa nanoparticles (100 mg/kg), and a group treated solely with N. sativa nanoparticles (100 mg/kg). The body weights were chronicled before …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 119–124 Read article
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Development of Biomass-Derived Composites From Commodity Plastics Via Pyrolysis For Enhanced Corrosion Protection of Metals
Abstract: Escalating environmental concerns and the depletion of fossil resources have spurred the need for sustainable and eco-friendly materials. By converting plastic waste into valuable carbonaceous materials via pyrolysis, both plastic pollution and resource scarcity can be addressed. The process involves the thermal decomposition of plastics in an inert atmosphere, producing a mixture of gases, liquids, and solid residues rich in carbon. These carbonaceous residues are then incorporated with biomass materials …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 59–70 Read article
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Optimizing Fin Parameters to Enhance Passive Heat Dissipation in Photovoltaic Panels
Abstract: This study explores passive cooling techniques to enhance the thermal management of photovoltaic (PV) modules, which is crucial for maintaining efficiency. A computational fluid dynamics (CFD) model, using ANSYS Fluent, was developed to evaluate three fin shapes: rectangular, trapezoidal, and triangular, attached to the back of PV modules. The study varied parameters such as fin count, thickness, and length to determine optimal configurations for cooling. Among the designs, triangular fins …
Published in International Journal of Radio Frequency Innovations · Vol. 2, Issue 2, 2024 · pp. 25–35 Read article
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Flame-Retardant Polymeric Materials: Recent Advances and Future Directions
Abstract: This review explores essential flame-retardant polymers that play a vital role in various industries such as electrical & electronics, automobile, manufacturing, and firefighting. This review also highlights the latest progress in the design and synthesis of flame-retardant polymers, highlighting novel approaches such as the incorporation of nanomaterials, bio-based flame retardants, and the use of intumescent systems. Recent advancements include high-throughput screening, computational design, bio-based and sustainable flame retardants, self-healing materials, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 125–132 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Charging System for Electric Vehicle and Hybrid Electric Vehicle in Running Condition: A Review
Abstract: This study examines comparative studies of three different charging systems used in electric vehicles while they are moving or operating. It also deals with the idea of using an alternator at each wheel of the vehicle to charge the non-connected set of batteries, as well as a brief explanation of the principles, mechanisms, design, and constraints of fuel cells, solar panels, and regenerative brakes. These are some of the most …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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Deformation and Densification Behaviour of Sintered Aluminium Alloy and Chromium Carbide Metal Matrix Preforms
Abstract: This paper presents comprehensive experimental results focused on the deformation and densification behavior of sintered AA2618 - 2% Cr3C2 metal matrix preforms. The study specifically examines preforms with varying aspect ratios subjected to a cold upsetting process. To create the powder preforms, an initial theoretical density of 89% was achieved using a cylindrical die on a 600 kN hydraulic press. The sintering process was conducted in an electric muffle furnace, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 125–131 Read article
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Physiotherapeutic Strategies to Enhance Throwing Accuracy in Cricket Players
Abstract: Background: Throwing accuracy is a crucial skill for cricket players, impacting both individual performance and team success. Physiotherapeutic strategies can enhance throwing mechanics, strength, and flexibility, leading to improved accuracy. Objectives: This study aims to outline effective physiotherapeutic interventions that optimize throwing accuracy in cricket players. Methods: A comprehensive review of current literature and practices was conducted with 3 articles found through PubMed, Google Scholar & Research Gate year range …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 30–34 Read article