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1971 articles for “advancements” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Enhancements in Titanium Matrix Composites: A Multifaceted Exploration of Various Structural Ceramics Reinforcement
Abstract: This research study delves into the comprehensive exploration of Titanium Matrix Composites (TMCs) reinforced with Silicon Carbide (SiC), Alumina (Al2O3), and Boron Nitride (BN). The investigation is structured into three key phases, each addressing essential aspects of TMCs: Phase 1 involves materials and manufacturing, where TMC coupons were fabricated through the stir casting technique with varying compositions of aluminum and silicon carbide. Phase 2 focuses on characterization and defect detection, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 83–94 Read article
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Fast Dissolving Oral Thin Films: A Review
Abstract: Fast-dissolving oral thin films (FDOFs) represent a significant advancement in drug delivery technology, offering advantages over traditional solid dosage forms, especially for patients with swallowing difficulties. FDOFs dissolve rapidly in the mouth, releasing the active ingredient without the need for water or chewing. They have picked up ubiquity due to their comfort, taste veiling capabilities, and progressed persistent compliance. Ideal drugs for FDOFs should possess characteristics such as solubility, stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 24–31 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Facial Biometrics Driven Attendance Automation Solution Using LBPH Algorithm
Abstract: In today's educational landscape, managing attendance remains a central administrative task, often conducted manually on paper, consuming valuable time for educators. This project proposes a solution utilizing facial recognition technology to streamline the attendance process, thereby saving time and maintaining accurate student records. The objective is to develop an automated attendance system that is minimally intrusive, cost-effective, and highly efficient, leveraging computer vision techniques and algorithms like local binary patterns …
Published in Journal of Open Source Developments · Vol. 11, Issue 1, 2024 · pp. 27–35 Read article
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Towards Green Energy: Assessing Biomass Densification Technologies for Power Generation
Abstract: Technologies for biomass densification have become essential for improving the profitability and efficiency of biomass-based energy production. This thorough review article examines several biomass densification-related topics, such as the technologies involved, process variables, benefits, difficulties, and possible uses. We explore the basic ideas behind biomass densification, including torrefaction, briquetting, and palletization, and we talk about the factors that affect their efficacy as well as their mechanisms. Furthermore, we examine the …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 43–53 Read article
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Therochemical Conversion of Biomass: An Overview
Abstract: A viable way to utilize biomass resources for energy production is through thermochemical conversion processes. This study presents a thorough analysis of the principles, workings, benefits, and drawbacks of thermochemical conversion processes, such as pyrolysis, gasification, and combustion. We examine the various uses of thermochemical conversion in waste management, biofuel synthesis, and energy production. We also go over recent developments, technological breakthroughs, and potential future paths for biomass thermochemistry research. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 31–42 Read article
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Transportation Applications of Solar Energy: Innovations and Consequences
Abstract: The transportation industry is at the forefront of sustainability issues due to its substantial reliance on fossil fuels, which raises air pollution and greenhouse gas emissions. As a result, engineers and researchers have discovered that solar energy is a practical substitute for powering a variety of transportation vehicles. This study looks at the state of solar energy applications in the transportation industry today, exploring cutting-edge technologies, practical implementation issues, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 2, 2023 · pp. 39–44 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Recent Development Technique in Management of Cancer
Abstract: Cancer develops when a change in one's genetic makeup leads to the development of tumour cells. These clusters of malignant cells eventually develop into tumours. Tumours can shed cancerous cells, which can then travel through the lymphatic system or the circulatory system to other organs. In the medical field, this occurrence is referred to as metastasis. Cancer cells proliferate even when they have no instructions to do so. Despite the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 25–41 Read article
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Analyzing Failures and Challenges in Oncology: Integration of Artificial Intelligence in Healthcare
Abstract: The present study focused on investigating the challenges and failures that had been embarked during the deployment of artificial intelligence technologies within the field of oncology in healthcare. Through precise research and statistical analysis, we aimed to elucidate the specific circumstances surrounding each failure, providing insights into the root causes, consequences, and subsequent developments. The present study was aimed to offer a detailed understanding of the challenges faced through artificial …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 42–50 Read article
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Optimizing Microbial Consortia for Enhanced Biofuel Production: A Metabolic Engineering Approach
Abstract: Biofuels, derived from renewable biomass sources, offer a promising avenue for reducing greenhouse gas emissions and mitigating environmental impact. Among the various approaches to biofuel production, microbial fermentation using microbial consortia has gained significant attention due to its potential for enhancing efficiency and sustainability. Microbial consortia, consisting of diverse populations of microorganisms, exhibit synergistic interactions between different types of microbes that can improve substrate utilization and metabolic robustness compared to …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 46–53 Read article
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Design and Development of Agrobot Using Feed Forward Network for Smart Farming Agriculture
Abstract: The Agrobot framework is a form of natural language processing that requires training to understand human language and meet user needs accordingly. The development of a chatbot tailored for the agricultural industry represents a significant advancement in agricultural technology. This chatbot serves as an interactive tool to assist farmers in various aspects of agricultural practices, including crop management, pest control, weather forecasting, and market information. The main objective of this …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 1, 2024 · pp. 6–14 Read article
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Reinforcement Learning in Real World Application: A Study on Robotics; Autonomous Vehicles and Industrial Automation
Abstract: This research paper investigates the practical application of reinforcement learning (RL) in three critical domains: robotics, autonomous vehicles, and industrial automation. The study delves into the implementation of RL algorithms to enhance decision-making, adaptability, and autonomy in these real-world scenarios. Through a comprehensive review of existing literature, methodologies, and case studies, the paper addresses the challenges faced and the successes achieved in deploying RL in each domain. The findings offer …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 3, 2023 · pp. 1–15 Read article
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Air Quality Monitoring Using IoT Cloud Framework in Underground Mining
Abstract: The quality of air is a major concern nowadays; this is due to its crucial impact on human beings. Maintaining a good and healthy environment in a closed area depends heavily on the atmosphere. The primary difficulty lies in upholding air quality within an enclosed workplace setting. The conventional way to measure the quality of air was to collect the air quality samples by the fixed instruments in fields and …
Published in Journal of Communication Engineering & Systems · Vol. 14, Issue 1, 2024 · pp. 46–65 Read article
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Mindwell: A Psychological Guide for Well-being
Abstract: Mental health is a crucial aspect of overall well-being, yet access to professional therapy remains a significant challenge for many individuals due to various barriers, including cost, availability, and stigma. This research aims to develop an accessible and effective mental health therapy chatbot, named Mindwell Psychology, leveraging the power of large language models (LLMs) and state-of-the-art natural language processing techniques. The primary objective of this study is to create a …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 1, 2024 · pp. 63–77 Read article
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Section Cutting in Histopathology: An Update
Abstract: Histopathology is the microscopic examination of tissues to diagnose and study diseases, more significantly the diagnosis of cancer. It plays a pivotal role in modern medicine, serving as the gold standard for definitive diagnosis in a wide range of conditions. Through meticulous analysis of tissue morphology (structure) and cellular characteristics, histopathology provides crucial information for disease classification, staging, and guiding patient management. In the world of histopathology, where microscopic details …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 29–34 Read article
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Speech Therapy in the Digital Age: Telepractice and Remote Interventions
Abstract: In the digital age, advancements in technology have revolutionized various aspects of healthcare, including speech therapy. This study explores the emergence and evolution of telepractice and remote interventions in speech therapy. Telepractice, interchangeably labelled as teletherapy or telehealth, denotes providing speech therapy services remotely using telecommunication technology. Its incorporation into speech therapy has broadened service accessibility, notably benefiting underserved or remote locales. Moreover, it has ensured uninterrupted care delivery during …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 42–46 Read article