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1260 articles for “CTLA-4”
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Polymeric Ion-Exchange Complexes of Carbomer for Taste Masking and Enhanced Drug Bioavailability: A Physicochemical and In Vivo Study
Abstract: Famotidine (FAM) was recognized as a crystalline powder that varies in color from white to pale yellow and possesses an extremely bitter flavor. This study aimed to conceal the unpleasant flavor of FAM through employing unconventional ion-exchange resins sourced from Carbomer polymer Evaluation (Carbopol 974P). We used FTIR, DSC, and XRD to look at the drug-resin combination in its hard form to learn more about its physical and chemical properties. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 727–740 Read article
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Formulation, Evaluation, and Stability Studies of a Topical Clotrimazole and Zinc Oxide Suspension with Enhanced Skin Protective Properties
Abstract: Background: Clotrimazole is a well-known antifungal agent frequently used in the treatment of various superficial fungal infections, while Zinc Oxide is a widely accepted skin protectant with soothing, astringent, and antimicrobial properties. Combining these agents in a topical suspension offers a dual therapeutic approach, enhancing both antifungal efficacy and skin protection. Objective: The objective of this study was to formulate, evaluate, and conduct stability studies on topical suspensions containing Clotrimazole …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 22–31 Read article
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Nano-Silica Reinforced Crosslinked Biopolymer–PCM Composites for Improved Thermal Cycling Durability
Abstract: Crosslinked biopolymer–PCM composites reinforced with nano-silica were developed to enhance thermal cycling durability, leakage resistance, and structural stability for advanced thermal energy storage applications. A starch-based biopolymer was chemically crosslinked using citric acid to create a stable polymer network, while paraffin was employed as the phase-change medium and nano-silica (1–4 wt%) served as a multifunctional inorganic reinforcement. FTIR analysis confirmed successful esterification between citric acid and the polymer backbone, indicated …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1–10 Read article
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Magnetic Metal–Polymer Composites with Ferromagnetic Particle Networks for EMI Shielding in Flexible Electronics
Abstract: The rapid expansion of flexible and wearable electronic systems has intensified the demand for lightweight, mechanically compliant materials capable of effective electromagnetic interference (EMI) shielding. In this study, magnetic metal–polymer composites with magnetically aligned ferromagnetic particle networks were developed and systematically investigated for EMI shielding in flexible electronics. Thermoplastic polyurethane (TPU) was employed as an elastomeric polymer matrix due to its excellent flexibility, dielectric characteristics, and compatibility with particulate fillers. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 25–39 Read article
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Effect of Toxoplasma gondii on some Neurotransmitter Levels in Patients with Toxoplasmosis Infection
Abstract: Background: The study of Toxoplasma gondii on some neurotransmitter levels in patients with toxoplasmosis infection is one of the challenges of sustainable development. Toxoplasma gondii is a parasite that can alter host behavior by affecting neurotransmitters of the host. Aim: To diagnose if there are differences in neurotransmitter levels in infected people by toxoplasmosis and healthy people to predict the psychological and neurological diseases. Methods: The study included collecting 60 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 1–8 Read article
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Interaction of Mosquito’s hppd Enzyme with Lansoprazole Sulfide A New Hope to Tackle the Mosquito Menace – an in-Silico Study
Abstract: Tyrosine detoxification is an important physiological process that helps blood-feeding insects, such as mosquitoes that transmit Plasmodium parasites causing malaria, digest their blood meals. An enzyme known as 4-hydroxyphenylpyruvate dioxygenase (HPPD), which is part of the tyrosine detoxification pathway, helps in removing excess tyrosine in a high-protein blood meal. Excess tyrosine can be lethal to the insects, and hence, the role of HPPD enzyme is very critical. Inhibitors of HPPD …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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Structure-Property-Process Relationships in BNNS-Modified PEEK Nanocomposites for High-Performance Applications
Abstract: This study reports the design and performance evaluation of boron nitride nanosheet (BNNS)-reinforced polyetheretherketone (PEEK) nanocomposites fabricated using melt compounding and high-temperature Fused Filament Fabrication (FFF). PEEK, a high-performance thermoplastic, was reinforced with BNNS at 0.5–5wt.% to enhance mechanical, thermal, and tribological functionalities for advanced engineering use. Composite filaments were extruded and printed using a modified Bambu Lab FFF printer. Mechanical testing revealed a peak tensile strength of 108 MPa …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 867–888 Read article
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Mechanical and Sustainable Enhancement of Epoxy Composites using Tamarind Seed Powder
Abstract: The investigation examines how tamarind seed powder affects epoxy-based materials for the development of waste-based useful products. The research examines the mechanical behavior of epoxy resin composites which contain tamarind seed powder in increasing percentages spanning from 10% to 40%. The team utilized the hand layup method to produce the composites which then fulfilled the ASTM guidelines for specimen fabrication for mechanical tests. The study examined fundamental mechanical parameters by …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 797–806 Read article
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Bio-Derived TPS–Lignin Hybrid Composites Reinforced with Modified Coir and Plantain Fibers for Eco-Efficient Structural Applications
Abstract: This study develops bio-derived polymer composites using a thermoplastic starch–lignin (TPS–lignin) matrix reinforced with alkali-treated coir and plantain fibers for sustainable load-bearing applications. The TPS–lignin matrix was formulated using cassava starch, glycerol, and 10 wt% lignin, while coir and plantain fibers were surface-modified using 5 wt% NaOH to enhance interfacial compatibility. Composite laminates were fabricated with varying fiber loadings (10–40 wt%) through melt-mixing and hot-press compression. Tensile, thermal, morphological, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 136–145 Read article
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Design and Computational Analysis of Hybrid Carbon Fiber-Enhanced Metal Matrix Composite Spur Gears
Abstract: The automobile industry has to find the alternative solution for steel grade gears to overcome the weight to high strength ratio and thermal consideration with high damping properties. This study describes the design, FEM analysis, and performance evaluation of three new hybrid composite spur gears: a monolithic carbon fiber/epoxy (80/20 weight percent) composite (A), and two hybrids with steel (B) and aluminum (C) matrices (64% CF, 21% Epoxy, 15% metal). …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 158–172 Read article
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A Gamified Digital Platform for Sustainable Farming Practices: Simulation, Statistical Analysis, and Water Resource Management Implications
Abstract: Sustainable farming practices play a critical role in enhancing agricultural water use efficiency, conserving limited water resources, and ensuring long-term food security under increasing environmental and climatic pressures. Despite their importance, farmer participation in conventional agricultural extension and training programs remains limited due to low engagement and a lack of sustained motivation. To address this challenge, this study proposes a gamified digital decision-support platform aimed at promoting sustainable agricultural and …
Published in Journal of Water Resource Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 13–24 Read article
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Structural Load Evaluation of a Low-Rise Residential Building (G+4) Using STAAD.Pro: A Review
Abstract: The structural analysis and design of multi-story residential buildings have become more complex because cities continue to grow while safety requirements become more demanding and building codes establish stricter requirements. The traditional methods of structural analysis worked through manual execution which required extended periods to complete and suffered from computational errors that primarily affected indeterminate structures and lateral loading conditions. This review paper providesa detailed evaluation of previous works related …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 40–45 Read article
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Design And Analysis of Carbon Filler Reinforced Composite Small Wind Turbine Blades
Abstract: Although wind turbines have great potential for capturing wind energy, their blades suffer from unstable aerodynamic loads as a result of operating for extended time in challenging conditions. Both structural and aerodynamic performance are negatively impacted by these loads. The effectiveness of the wind turbine and the use of wind energy are significantly impacted by the choice airfoil. Commonly used airfoils include NACA 4412, NACA 23012, and SG6043. The lift …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 79–89 Read article
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A Case Study on the Efficacy of Sanshamana Chikitsa in Vitiligo (Shwitra)
Abstract: Background: Vitiligo (Shwitra), a pigmentary disorder characterized by the loss of melanocytes, the skin cells responsible for melanin production. This results in the appearance of white or depigmented patches on the skin, is interpreted in Ayurveda as a Tridoshaja condition primarily involving vitiation of Pitta and Rakta. Vitiligo poses a major psychological burden in addition to being a cosmetic issue due to its visible appearance and associated social stigma. Objective: …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 29–38 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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A study of The impact of Antibiotic Pollution and The types of Environmental Pollution It causes
Abstract: Antibiotics are essential biological drugs for human health and are the cornerstone of treating infections caused by various bacteria and viruses. However, they also pose a significant risk if misused, as each antibiotic is designed for a specific type of bacteria. Sometimes, due to the evolution of bacteria, many antibiotics have become ineffective and resistant to contamination and infection. Therefore, they can have the opposite effect, polluting the environment instead …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 41–46 Read article
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Characterization of Bamboo-Fiber Reinforced Geopolymer Composites
Abstract: In this project, we plan to produce and assess a new, eco-friendly composite made from geopolymer (from a combination of fly ash and GGBFS), strengthened with chemically treated bamboo fibres for retrofitting earthquake-resistant buildings. Geopolymer is produced by activating a mixture of fly ash and GGBFS with sodium silicate and sodium hydroxide solutions. We have produced and analyzed bamboo fibre-reinforced geopolymer composites as potential materials for seismic retrofitting of structures …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1007–1025 Read article
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Performance Evaluation of PET Strip Fiber Reinforced Concrete
Abstract: Polyethylene Terephthalate, commonly known as PET, is a petroleum-based plastic polymer that is widely used in the packaging of various commodities due to its durability, and poses a major threat to the environment. To tackle this scenario, the construction industry is researching all possibilities to incorporate this waste into concrete and enhance the properties of concrete. The present study evaluates the performance characteristics of M 30 grade concrete when reinforced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1076–1088 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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A Retrospective Analysis of Resin-Based Polymer Composites and Bioactive Glass-Polymer Hybrids Regarding Secondary Caries and Durability
Abstract: Aim- To compare the 2-year clinical survival and failure modes of a Resin-Based Polymer Composites and BioactiveGlass-Polymer Hybrids in Class I and II posterior restorations. Methods-A total of 550 restorations were placed in adult patients across various private dental practices in India to ensure a diverse clinical demographic. Teeth were randomly assigned and restored with either a hybrid composite (Te-Econom, IvoclarVivadent; n=275) or a Resin-Modified Glass Ionomer Cement (GC Gold …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1089–1095 Read article