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177 articles for “type I diabetes”
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Therapeutic Effects of Metformin on Cancer: A Possible Option in Cancer Chemotherapy
Abstract: Metformin is being used for an elongated period of an antidiabetic medicine for type 2 diabetes. It is used moreover as a monotherapy or in mixture with additional antidiabetic medications. The drug derived into importance in diabetes and other circumstances with cardiovascular risk after the landmark study of 1995 by the United Kingdom Prospective Diabetes Study which highlighted its reputation. The usage of metformin, the usually given drug for type …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 1, 2023 · pp. 46–68 Read article
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Limitations to Therapeutic Approaches to T2DM in Light of Different HbA1C Values Suggested by Different Scientific Associations: A Review
Abstract: The present article provided a comprehensive review of international and national guidelines for managing Type-2 diabetes, with a focus on personalized treatment strategies. It discussed the recommended glycated haemoglobin targets and the initial treatment approach involving lifestyle modifications and the use of metformin. The present article underlined the necessity for treatment intensification due to the progressive nature of type-2 diabetes. It also emphasized the complexity of selecting additional antidiabetic medications, …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 2, 2023 · pp. 13–26 Read article
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A Study to Assess the Add-on Impact of Ayurvedic Management along with Ongoing Conventional Treatment of Diabetes Mellitus: A Randomized Clinical Trial
Abstract: Diabetes affects millions and thus is a major public health disease among with adults aged 30+. Available treatment although helps but many develop other side effects to complicate the issue. Ayurveda offers options to manage diabetes without complications. Present study is to see the add-on effect of Ayurveda therapy among persons on modern medicines. Ayurveda D4 combination is Jamunbeej and Gudmarpatra 5 gm churna each before breakfast and dinner and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 10, Issue 4, 2023 · pp. 15–22 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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A Review on The effect of Polycystic Ovary Syndrome on some Hormonal and Metabolic Disturbances in Women
Abstract: Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age. It usually begins to appear during adolescence. The ovaries produce an abnormal amount of "androgens", which are male sex hormones that are usually found in women in small quantities. Ovarian syndrome causes hormonal imbalances, irregular menstrual cycles, increased cysts in the ovaries, in addition to hair growth all over the body, acne, and pain in …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 21–28 Read article
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A Study to Assess the Add-on Impact of Ayurvedic Management along with Ongoing Conventional Treatment of Diabetes Mellitus: A Randomized Clinical Trial
Abstract: Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disbalance of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, action, or both. Diabetes affects millions and thus is a major public health disease among with adults aged 30+. Available treatment although helps but many develop other side effects to complicate the issue. Ayurveda offers options to manage diabetes without complications. Present study …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 1, 2021 · pp. 15–22 Read article
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Knowledge, Attitude and Practices Towards Insulin Therapy Among Diabetic Patients in Jimma University Specialized Hospital, Southwest Ethiopia
Abstract: Insulin is mandatory for the treatment of type 1 diabetes mellitus (DM) and it may also be required for other types of DM as the disease progresses. Once started patients have to take the drug for lifelong and they face many problems such as problems of injections, storage of insulin, dose and how to take the injection. The aim of this study was, therefore, to assess the knowledge, attitude and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 2, 2018 · pp. 1–10 Read article
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Exploring The Multitarget Pharmacological Mechanism of Diabex for T2dm by Combining Network Pharmacology and Molecular Docking Techniques
Abstract: Objective: Hyperglycemia brought on by an absolute or relative absence of insulin synthesis or action characterises a set of illnesses known as diabetes mellitus. Chronic hyperglycemia in diabetes mellitus has been linked to organ damage, heart, and blood vessels. The persistent metabolic condition Diabetes is a severe global issue with negative social, health, and economic effects. It is a type of metabolism disorder that interferes with food digestion in the …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 3, 2023 · pp. 62–73 Read article
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PREVENTION AND CONTROL OF DIABETES MELLITUS (DM) WITH DIETOTHERAPY: A REVIEW
Abstract: Prevalence of type II diabetes mellitus (T2DM) have been increasing throughout the world day by day, to an extent that the condition has reached the epidemic proportions in many countries. One of the main reasons for increasing diabetic cases is the sedentary lifestyle, intake of junk food and obesity. Unhealthy eating with profound dependence on junk food, is the major reason for increasing lifestyle diseases like Diabetes Mellitus. Greco-Arab and …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 10–19 Read article
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Timely Diabetes Possibility Prediction Using AI Techniques
Abstract: The fastest chronic life-threatening disease affecting more than 422 million people globally is diabetes. The primary causes of type 2 diabetes are lifestyle choices and environmental factors. It is a slowgrowing disease which starts to develop metabolic factors long before they evolve into a disease and is formally diagnosed by a fasting sugar test. There are records of indications related to diabetes from 520 patients in the dataset that was …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 9, Issue 2, 2022 · pp. 37–47 Read article
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Yoga Practice for the Prevention and Management of Diabetes Mellitus: A Systematic Review
Abstract: Yoga is an ancient art or science, beneficial for the development of body, mind and spirit. Diabetes represents a spectrum of metabolic disorders, which has become a major health challenge worldwide. Various ancient books mentioned the usefulness of Yoga in the prevention and management of certain diseases. Now, it has become the subject of modern scientific evaluation of this ancient evidence. The present study was planned to review the published …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 1, 2017 · pp. 31–35 Read article
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In vitro Quality Control Testing: A comparative Study of Jan Aushadhi with Different Brands of Metformin Tablets Available in India
Abstract: Metformin hydrochloride is an oral anti-diabetic drug used mainly to treat type-II Diabetes Mellitus and it is widely available in different brands in the market, making it challenging to select the safe, effective and economic one. The endeavour of this experiment was to compare and assess the quality standard of the Jan Aushadhi medicine with a different brand of the metformin hydrochloride tablet available in India. For evaluation of the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 32–37 Read article
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Recombinant Lactobacillus helveticus PJ4-Down Regulates TLR4 Mediated Inflammatory Responses in Sucrose Induced Diabetic Rats: A Novel Therapeutic Approach
Abstract: High sucrose diet (HSD) is known to induce type 2 diabetes. Recombinant Lactobacillus helveticus PJ4 was constructed to express the InuJ gene under the xylose promoter resulting in the secretion of inulosucrase enzyme in gastrointestinal tract which polymerizes the fructose moiety of sucrose to inulin type fructans. L. helveticus (pSLP-InuJ-Vhb) transformant (LHI) was intragastrically administered to rats fed with HSD diet. The composition of fecal microbiota and short-chain fatty acids …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 44–65 Read article
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In Vitro Studies on α-Amylase Inhibitory Activity of the Leaves of Peltophorum pterocarpum (DC.) Baker ex Heyne
Abstract: AbstractThe present investigation evaluates the in vitro anti-diabetic activity of ethanolic extract of leaves of Peltophorum pterocarpum by α- amylase enzyme inhibitory activity. Besides, this qualitative phytochemical analysis of the plant was carried out. Preliminary phytochemical screening of the extract revealed that the presence of different types of compounds including flavonoids and steroids. The α-amylase inhibitory activity of ethanolic extract showed concentration dependent manner. Hence, α-amylase enzyme inhibition may be …
Published in Research & Reviews : Journal of Botany · Vol. 5, Issue 3, 2016 · pp. 16–20 Read article
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History, Processing, Types and Health Benefits of Indian Yogurt
Abstract: Yogurt is a food which is nutrient rich and it is produced after the milk bacterial fermentation. Yogurt should have 3.25% milk fat and 8.25% milk solids non fat and the titrable acidity of at least 0.9%, which is expressed as lactic acid. Before adding bulky flavoring additives, the USDA yogurt criteria specify that the yogurt must satisfy the composition requirements of milk fat and MSNF. The data used in …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Tirzepatide : Treatment For Diabetes Mellitus II & Obesity
Abstract: Tirzepatide is a novel medication that the FDA has approved to treat type 2 diabetes mellitus. Tirzepatide is used off-label to treat obesity because` of its powerful weight-loss effects. It Known as the "twin epidemics," the prevalence of obesity and diabetes is a growing issue worldwide, particularly in wealthy nations. Therefore, cutting-edge therapeutic strategies are required. Tirzepatide, Known as a "twincretin," tirzepatide is the only dual glucagon-like peptide-1 (GLP-1) and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 23–32 Read article
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Management of Steroid Induced Diabetes with Unani Medicine: A Case Report
Abstract: Background: Glucocorticoids (GC), such as prednisolone, are commonly used for their anti-inflammatory and immunosuppressive properties. However, chronic GC use can lead to adverse effects, including diabetes. This case study evaluates the efficacy of Arq Afsanteen, an Unani compound drug, in managing GC-induced diabetes. A 50-year-old man with a family history of type 2 diabetes and a history of partial gastrectomy was diagnosed with sarcoid tuberculosis and began treatment with ATT …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 49–53 Read article
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Prevalence of Risk-Factors of Non-Communicable Diseases among Rural Adults
Abstract: Non-communicable diseases are the leading cause of death in the world, as well as in India. India is facing a growing burden of non-communicable diseases. NCDs accounts for 53% of deaths in India in 2008. The four main types of non-communicable diseases are cardiovascular diseases (like heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructed pulmonary disease and asthma) and diabetes. The important risk factors identified for …
Published in Journal of Nursing Science & Practice · Vol. 6, Issue 1, 2016 · pp. 43–48 Read article
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Maternal and Fetal Consequences of Vitamin D Deficiency during Pregnancy: An Overview
Abstract: Apprehensions exist about the adequacy of vitamin D in pregnant and lactating women. Maternal vitamin D status influences maternal, fetal, and breast-fed infant bone health; maternal adverse outcomes (bone health, gestational diabetes, obstructed labor, preeclampsia, and infectious disease); fetal adverse outcomes (growth, bone health, gestational age, intrauterine growth, type 1 diabetes, asthma, immune development and cardiac disease); and infant adverse outcomes. Throughout pregnancy, maternal vitamin D standing may be of …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 12–28 Read article
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The Interactive Morbidity of Bipolar II Disorder and Obsessive-Compulsive Disorder
Abstract: Bipolar II disorder (bipolar disorder) interacts with obsessive-compulsive disorder (OCD) in a synergistic pattern during its symptomatic course. The relationship of the disorders is overall negative in terms of treatment outcomes and more risky and severe in its comorbid form (i.e., in terms of higher probability of hospitalization or incarceration). Somatic disease should be considered in cases presenting with the symptomology of any form of bipolar disorder as certain illnesses …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 10–13 Read article