STM Journals Peer-reviewed research from Consortium e-Learning Network

Research and Reviews: A Journal of Medicine

Limitations to Therapeutic Approaches to T2DM in Light of Different HbA1C Values Suggested by Different Scientific Associations: A Review

  1. Teja Sree Bitla
  2. Ravishankar Polisetty
  3. Purna Divya Singanamala
  4. Shaik Aminabee

Abstract

The present article provided a comprehensive review of international and national guidelines for managing Type-2 diabetes, with a focus on personalized treatment strategies. It discussed the recommended glycated haemoglobin targets and the initial treatment approach involving lifestyle modifications and the use of metformin. The present article underlined the necessity for treatment intensification due to the progressive nature of type-2 diabetes. It also emphasized the complexity of selecting additional antidiabetic medications, which considers various patient-specific factors and the therapeutic characteristics of the drugs. Despite the presence of extensive treatment choices and established guidelines, it was emphasized that a considerable number of patients were unable to attain favourable metabolic control. The present article concluded with a discussion on the glucose utilization of different organs in conscious rat’s post-endotoxin treatment, illustrating the differential responses of various organs.

Keywords

Support