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89 articles for “stress calculation”
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High-Performance Liquid Chromatographic Assay of Nateglinide and its Stability Study
Abstract: Nateglinide (NTG) is a D-phenylalanine derivative used in the treatment of type-2 diabetes mellitus. An accurate, sensitive and reproducible high-performance liquid chromatographic (HPLC) method has been developed and validated for the quantification of NTG in pharmaceutical samples. The drug was eluted from Inertsil ODS 3V (150×4.6 mm; 5 µm particle size) column at 30á´¼C with a mobile phase consisting of phosphate buffer of pH 3.3 and methanol (70:30 v/v). The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 41–52 Read article
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Failure Analyses of 16 mm Thick SA 516 GR 70 Auto Clave
Abstract: With the acceleration of global industrialization, there is a demand for high-or low-pressure storage of liquids or gases. Because of the complicated operating conditions that will inevitably encounter a possible hazard, pressure vessel design is a critical responsibility. Previous failure studies have revealed that the presence of local loads and discontinuities increases pressure vessel fracture. As a result, a detailed examination of pressure vessel steel from the standpoint of fracture …
Published in Trends in Mechanical Engineering & Technology · pp. 21–30 Read article
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Efficiency analysis of the floating breakwater with mooring system
Abstract: Floating structures are new advance method for the water based structures. Floating structures can eliminate land issue. The floating structures are being used since ancient time for emergency and temporary purposes. For permanent structures the floating structure should overcome and completely resistant to water forces i.e. wave forces, water current forces, and wind forces and water static forces. In which the wave forces and water forces are major forces which …
Published in Journal of Offshore Structure and Technology · Vol. 11, Issue 2, 2024 · pp. 50–56 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Simple, Direct and Stability-Indicating UV Spectrophotometric Assay of Pioglitazone Hydrochloride in Pharmaceuticals
Abstract: Pioglitazone hydrochloride (PGH) is an antihyperglycemic agent used in the treatment of type-2 diabetes mellitus. A simple and straight forward UV-spectrophotometric method is presented for the determination of PGH in bulk drug and tablets by measuring the absorbance of drug solution in 0.1M H2SO4 at 269 nm. A plot of absorbance versus concentration obeyed Beer’s law over 2–36 µg ml-1 concentration range (r = 0.9981) with a molar absorptivity of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 7–16 Read article
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Nurses’ Attitude and Its Contradictory Factors Towards Nursing Profession
Abstract: Background: Many studies have confirmed that nursing has job related stress. The aim of study was to examine nurses' attitude towards nursing profession with their contradictory factors such as hospital management unease, work environmental discomforts, etc. Method: The descriptive correlational study was conducted on registered staff nurses of two multispecialty hospitals of Nadiad city. 80 nurses were selected with purposive sampling technique. A structured questionnaire and a self-administered five-point Likert …
Published in Journal of Nursing Science & Practice · Vol. 12, Issue 3, 2022 · pp. 24–30 Read article
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Cubic B-splines for Isogeometric Analysis of Laminated Composite Plates Subjected to Hygroscopic Loading Using Classical Laminated Plate Theory
Abstract: Composite laminates are inevitably used in several engineering structures due to their high strength and stiffness to weight ratio. The laminates are subjected to change in moisture content and the flexural behavior leads to change in the strength. Presence of moisutre may induce residual stresses and strains. Isogeometric analysis is a well-proven method to perform analysis of laminated composite plates. The main focus of this study is to apply isogeometric …
Published in Journal of Polymer & Composites · pp. 19–32 Read article
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Cubic B-splines for Isogeometric Analysis of Laminated Composite Plates Subjected to Hygroscopic Loading Using Classical Laminated Plate Theory
Abstract: Composite laminates are inevitably used in several engineering structures due to their high strength and stiffness to weight ratio. The laminates are subjected to change in moisture content and the flexural behavior leads to change in the strength. Presence of moisutre may induce residual stresses and strains. Isogeometric analysis is a well-proven method to perform analysis of laminated composite plates. The main focus of this study is to apply isogeometric …
Published in Journal of Polymer & Composites · Vol. 9, Issue 3, 2021 · pp. 19–32 Read article
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Laser stimulated downward combustion propagation phenomenon
Abstract: Enhanced energy requirement has necessitated active research efforts to understand combustion behaviour in presence of alternative energy sources. In the last five decades, emphasis on combustion focuses on two aspects viz., improving quality of combustion and addressing the risks/hazards. With recent advancement, an aspect which is researched upon is the combustion behaviour in the presence of laser flow. Their applications pertain to propulsion, energy generation, artillery, fire safety and defence …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 9, Issue 1, 2020 · pp. 32–43 Read article