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217 articles for “pathogenic infection”
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Global Emergence of mcr-mediated Colistin Resistance in Gram-negative Bacteria: Focusing the Current Status in India Under One Health Lens
Abstract: In the global crisis of antimicrobial resistance (AMR), colistin has been revived as a last resort treatment option for multidrug-resistant (MDR) Gram-negative bacterial infections. Rapid dissemination of mobilized colistin resistance (mcr) genes among Gram-negative bacterial pathogens is alarming the healthcare fraternity throughout the world, especially in developing countries such as India compromises infection prevention practices and reduces colistin efficacy during medical emergencies.. Several developed countries have implemented strict regulations on …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 3, 2022 · pp. 6–18 Read article
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A Review on Repurposing Drugs for Treatment of Covid-19
Abstract: The newly emerged 2019 novel coronavirus is named as severe acute respiratory syndrome 2(SARS CoV-2). Till date, 1,757,393 cases have been observed in India and 37,452 deaths. COVID-19 has been now declared as pandemic and new treatments are urgently needed as we enter a phase beyond containment. In the absence of approved marketed drugs against coronavirus, the treatment and management of novel COVID-19 disease worldwide is a challenge. Developing new …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 16–22 Read article
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Investigation on the Efficacy of Leaf Extract of Goat Weed, Ageratum conyzoides on NR Biophysiological Characteristics of Black Gram Vigna mungo Infected with Root–Knot Nematode Meloidogyne incognita
Abstract: Root-knot nematodes, Meloidogyne sp. are economically important plant pathogens affecting root system that can be managed by cultural practices, chemical nematicides and resistant cultivars. Use of nematicides for the management of root knot nematodes are being restricted due to environmental and human health concerns in addition nematicides often do not provide long term suppression of the pathogens. Therefore, there is a need to develop alternate ecofriendly management strategies for the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 1, 2014 · pp. 5–9 Read article
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Dermatophytoses: Taxonomy, Pathogenesis, Diagnosis, Resistance, and Management.
Abstract: Dermatophytes, belonging to the family Arthrodermataceae, are keratinophilic fungi responsible for superficial mycoses. Dermatophytoses affect the skin, hair, and nails globally. Over the last few years, dermatophytic infections have seen a sharp rise in India, with the main causative agent being antifungal-resistant Trichophyton mentagrophytes genotype VIII. This review provides a detailed overview of dermatophytoses, including taxonomy, pathogenesis, epidemiology, diagnosis, and treatment. Dermatophytes belong to the kingdom Fungi, family Arthrodermataceae, with …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 28–37 Read article
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Antibacterial Activity of Enicostemma Axillare Against Wound Pathogens
Abstract: The leaves extracts of Enicostemma axillare are used in traditional medicine for treatment of various infections. The antibacterial activity detected was against S.aureus, E.coli, Pseudomonas aeruginosa, P.vulgaris and K.pnemoniae. Wound swabs obtained from ten injured patients at Government hospital, led to the isolation of bacteria using standard methods, the microorganisms were isolated. Then chloroform, methanol and aqueous extract of Enicostemma axillare against S.aureus, E.coli, Pseudomonas aeruginosa, P.vulgaris and K.pnemoniae exhibited …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 4, Issue 3, 2014 · pp. 1–3 Read article
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Studies on Isolation of Fungal Species Associated with Healthy and Infected Aloe vera Leaves Collected from Jabalpur Region
Abstract: Aloe vera is one of the highly valued medicinal plant, known for its gel filled leaves. The leaf rot disease caused by pathogenic fungi is the common cause of deterioration of gel quality and economic losses. In order to control the phytopathogenic fungi, use of endophytic and phylloplane fungi is an increasing trend. The present study was carried out to isolate the fungal species from healthy and infected leaves of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 147–155 Read article
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Antimicrobial Activity of Alcoholic and Aqueous Extracts of Tinospora cordifolia
Abstract: 1024x768 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The success of chemotherapy lies in the continuous search for new drugs to counter the challenge posed by resistant strains. Ethanolic and aqueous extracts of plant Tinospora …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 1, 2011 · pp. 1–6 Read article
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Cell Membranes as Therapeutic Targets: Implications in Infectious and Metabolic Disorders
Abstract: This is a review of the crucial role played by cell membranes in health and disease with respect to their contribution to infectious and metabolic diseases. Dysfunction of membranes, such as membrane transporter changes and changes in lipid content, has been associated with a variety of diseases, including diabetes, cardiovascular disease, and cancer. The present therapeutic approaches are focused on attacking membrane constituents by disrupting the entry of pathogens or …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 47–53 Read article
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Curvularia spp. and Curvularia Infections: A Comprehensive Review
Abstract: Curvularia spp., dematiaceous (melanin-pigmented) fungi in the family Pleosporaceae, emerge as opportunistic pathogens that cause phaeohyphomycosis, allergic fungal rhinosinusitis, and keratitis. This review dissects their pathogenesis via melanized cell walls, conferring tissue invasion, protease secretion, and immune evasion in immunocompromised hosts. Clinical manifestations span cutaneous (70%), sinopulmonary (20%), disseminated (5-10%), and CNS forms, mimicking aspergillosis or mucormycosis. Laboratory diagnosis hinges on histopathology (irregular septate hyphae, 3-8 µm, brown on Fontana-Masson), …
Published in International Journal of Fungi · Vol. 3, Issue 2, 2026 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
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Insilico Structural Analysis and Homology Modeling of Crustin Protein from Fiddler Crab Species
Abstract: In terms of biomass and ecological or economic importance, the crustacea are the largest, most noticeable, and possibly, the most significance group of marine or aquatic arthropods. Because of their enormous commercial value and the necessity to prevent disease outbreaks in the shellfish aquaculture industry, decapods are the experimental animals of choice for practically all biological studies involving immune responses. Antimicrobial host-defense peptides (AMPs) are major components of metazoan immunity, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Mucosal Defense Mechanism in Fish: An Overview
Abstract: Mucosal surfaces are important physical barriers whose main function is to protect the systemic environment of the body against microbial invasion. It is the first line of defense to protect the animal and also functioning as an active immune tissue. Four mucosal-associated lymphoid tissues (MALTs), which start the immune responses are skin, gills, gut, and nose, have been reported in fish. Humoral and cellular immunity, their regulation and the factors …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 1–5 Read article
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Monkeypox Virus (MPXV): Epidemiology, Pathogenesis, and Control Strategies: Exploring the Recent Resurgence of Monkeypox, Its Transmission Dynamics, Clinical Manifestations, and Public Health Responses
Abstract: Monkeypox virus (MPXV) has re-emerged as a significant public health concern, with increasing cases reported worldwide. This zoonotic virus, primarily endemic to Central and West Africa, has demonstrated the potential for human-to-human transmission, leading to outbreaks in non-endemic regions. Unlike smallpox, which was eradicated through mass vaccination, monkeypox continues to persist due to the lack of widespread immunity and effective antiviral treatments. The resurgence of MPXV in recent years, particularly …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 29–34 Read article
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THE BURDEN OF EMPIRICAL THERAPY: ANALYZING THE PREDOMINANCE OF BROAD-SPECTRUM ANTIBIOTIC USAGE IN LOWER RESPIRATORY TRACT INFECTIONS
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Tiryaq-E-Arba (A Poly Herbal Unani Formulation) in Fighting Against COVID-19 Like Conditions–Unani Perspective
Abstract: Coronavirus disease 2019 (COVID-19) is a pandemic disease of modern time with unique and rapid transmission rate and affected almost all the nations without respecting any border. World Health Organization stated it is an infective disease and pandemic. The coronavirus disease 2019 (COVID- 19) which created in Wuhan, China, has now spread to 192 countries and organizational regions infecting nearly 800,000 persons of all ages as of 31 March 2020. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 4, 2021 · pp. 31–37 Read article
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Food Borne Pathogens: A Threat to Dairy Industry
Abstract: Food borne diseases is the major concern along with malnutrition in developing countries and developed countries as well. Milk is rich source of nutrition with large number of pathogenic bacteria which are more susceptible to cause illness or death. Millions of people stuck with food borne outbreaks throughout the globe because of presence of pathogenic bacteria – disease causing microbiota like E. coli O157:H7, Salmonella, Shigella, Listeria, Campylobacter, S.aureus and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 4, Issue 1, 2015 · pp. 28–36 Read article
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Study of Parasites of Human Importance from Cow Dung
Abstract: The present study was conducted to find out the prevalence of parasite from cow dung from different areas of Kolkata, India. The study included collection, isolation and characterization of parasites from cow dung. Wet mount and modified Ziehl Neelson staining techniques were used to isolate parasite. The prevalence was found to be 34% for Entamoeba histolytica and 16% for Cryptosporidium parvum. Approximately 50% of cattle were found infected with one …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 19–24 Read article
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Covid 19: Virology, Pathogenesis, Epidemiology and Control
Abstract: AbstractThe pneumonia caused by novel coronavirus (SARS-CoV-2) in Wuhan, China in December2019 is a highly infectious disease. Coronavirus disease spreads primarily through contact with an infected person when they cough or sneeze. It also spreads when a person touches a surface or object that has the virus on it, then touches their eyes, nose, or mouth. The World Health Organization (WHO) has declared the ongoing outbreak as a global public …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 2, 2020 · pp. 6–17 Read article
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A Short Review on Mucormycosis/Black fungus
Abstract: The present article provides an outline regarding the mucormycosis, an angio invasive infection and an opportunistic condition with fungal infection that mainly targets the people who are with weaker immunity unable to fight with environmental pathogens due to other health related problems and people who are on long term medication and the present paper has been covered with all the information regarding the Predisposing factors, suspected diseased conditions, Targeted organs/tissues …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 12–15 Read article
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Disease X: Unveiling the Unknown Pathogen and Enhancing Global Preparedness
Abstract: “The concept of “Disease X” was introduced to drive the creation and refinement of versatile technologies such as vaccines, therapeutic drugs, and diagnostic tests, which could be swiftly adapted and utilized in response to future infectious disease outbreaks with epidemic or pandemic potential. The aim was to establish a proactive approach to emerging health threats by developing platform technologies capable of addressing a broad spectrum of potential pathogens. The COVID-19 …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 15–20 Read article