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312 articles for “optimal path”
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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Optimizing Heat Transfer in Rectangular Channels with Turbulators: A Comprehensive Review
Abstract: Turbulators and various obstructions strategically placed along the airflow path in a channel are employed to enhance heat transfer This enhancement is achieved by disrupting the laminar sub-layer or intensifying turbulence within the duct passage. Numerous types of turbulator elements have been extensively utilized to optimize the heat transfer characteristics in such systems. Investigating further, researchers have explored the application of roughness elements in two-dimensional, three-dimensional, and irregular shapes. This …
Published in Journal of Experimental & Applied Mechanics · Vol. 14, Issue 3, 2023 · pp. 7–17 Read article
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Human Milk and Infant Growth: A Systematic Review of Nutritional Outcomes
Abstract: Human milk is recognized as the optimal source of nutrition for infants, playing a critical role in their growth and development. This systematic review explores the evidence linking human milk consumption to various growth parameters in infants, including weight gain, length, and head circumference while considering the influencing factors of prematurity and health status. The composition of human milk, rich in essential macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
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Hybrid Additive-Subtractive Manufacturing of Multi-Material Functionally Graded Components: Integration of Laser Powder Bed Fusion with High-Speed CNC Finishing for Aerospace Applications
Abstract: The synergy involved in the merging of additive and subtractive manufacturing technologies is the game changer to generate multi-material functionally graded components to be used in the aerospace industries. The paper is an in-depth review of a proposed hybrid additive-subtractive manufacturing, which synergistically merges laser powder bed fusion (LPBF) fashioning with rapid computer numerical control finishing production processes. The multi-material deposition, thermal issues, and optimization of post-processing are the challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 398–418 Read article
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Numerical Analysis of Thermal Performance of Cylindrical Perforated Pin Fins for Aligned Arrangement
Abstract: Present paper investigates the thermal characteristics pertaining to laminar forced convection heat transfer enhancement achieved in a flat surface mounted with cylindrical perforated pin fins in a rectangular channel having a area of cross section 280 x150 mm2.The analysis was done for the range of angle of perforated holes from 00 to 600 for a constant value of Reynolds Number and fixed fin spacing of 40 mm using air as …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 7, Issue 1, 2020 · pp. 8–16 Read article
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Microbial Contaminants in Commercial Beverages: Health Concerns and Suggestive Preservative Methods
Abstract: AbstractFruit juices are the important source of vitamins, minerals and antioxidants, essential for the growth and development of every human. However, due to the presence of various nutritive components, it provides optimal conditions for the growth of food microorganisms. Various pathogenic and non-pathogenic bacteria, fungus, yeasts and parasites are found to be associated with fruit juices. Many of these microbes generally enters at the time of packaging and cause various …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 1–10 Read article
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Project Management Using Topological Sorting
Abstract: Project management is a complex process involving planning, coordinating, and managing resources to accomplish certain goals within specified time frames. Topological sorting is a method used in graph theory to arrange nodes in a Directed Acyclic Graph (DAG) in order of their dependencies. This method can be used to determine the order in which tasks must be accomplished in order to successfully complete the project. Topological sorting helps identify the …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 10, Issue 1, 2023 · pp. 6–12 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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The Role of Optimization and Probability in Shaping Artificial Intelligence
Abstract: This study discusses the basic roles of optimization algorithms and the theory of probability in the process of evolution and development of Artificial intelligence (AI). First, we introduce the role played by the next generation of leading-edge optimization algorithms developed since gradient descent to evolutionary strategies with respect to the learning of high-level AI models and how to enable them to learn to effectively explore high-dimensional parameter spaces. At the …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 123–128 Read article
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A REVIEW ON RECENT TRENDS AND CHALLENGES IN MICROMACHINING AND MACHINABILITY OF Ti-6Al-4V
Abstract: Based on several literature examinations from past decades, it is clearly observed that limited research has been done till date concerning to micromachining and had a partial understanding of it with focus on miniaturized parts. This review article presents a complete comprehensive on machining process at micro level with attention in drilling for work horse of titanium alloys. The Ti and its alloys are the most attractive materials due to …
Published in Trends in Mechanical Engineering & Technology · Vol. 8, Issue 3, 2018 Read article
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Optimization of Process Parameters of Two Way Abrasive Flow Machining by Grey Relational Analysis Coupled with Principle Component Analysis
Abstract: Now a days as the advancement of technology is increasing rapidly, expectation of human, from industry also increased. To fulfil these expectations new technologies are coming into existence. In this regard unconventional machining processes are playing an important role. Abrasive flow machining is a non-traditional finishing process used for finishing parts with predominantly irregular geometry. In AFM, material removal and surface finish takes place by flowing visco elastic abrasive carrier …
Published in Journal of Experimental & Applied Mechanics · Vol. 6, Issue 2, 2015 · pp. 44–56 Read article
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Adaptive Routing Protocol to Optimize the Quality of Service of MANET Using Neural Network
Abstract: A MANET is a group of mobile nodes that create a temporary network without relying on centralized administration or standard supporting devices, often functioning as a conventional network. These dynamic environments present significant challenges for traditional routing and switching protocols, particularly in delivering Quality of Service (QoS) benchmarks such as bandwidth, latency, packet delivery ratio, and robustness. This study proposes an Adaptive Routing Protocol (ARP) leveraging Neural Network (NN) techniques …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 3, 2025 · pp. 01–09 Read article
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Integrating Biotechnology, Physiology, and Agroecological Practices for Sustainable Crop Production and Protection
Abstract: Global agriculture is currently confronting a wide range of complex challenges, including a rapidly growing population, climate change, increasing pest and disease pressures, soil degradation, water scarcity, and the urgent need for sustainable intensification of crop production. Addressing these issues requires integrated strategies that combine crop improvement (through modern breeding and biotechnology), precision agronomic practices related to soil, irrigation, and nutrition, as well as advancements in plant physiology, molecular biology, …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Comparison Analysis of Transformer Boosting and Induced Degeneration Topology Design of LNA for Millimeter Wave Frequency Range Using Polymeric Substrates
Abstract: In this study, a comparison between transformer boosting and source degeneration LNA topologies is conducted using two polymeric substrates—Polyimide (PI) and Liquid Crystal Polymer (LCP)—for millimeter-wave (mmWave) applications. With growing interest in flexible and high-frequency electronics, polymeric materials offer unique advantages such as low dielectric constants, mechanical flexibility, and thermal stability. The analysis explores gain, return loss, and noise figure performance while evaluating the influence of dielectric properties on the …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 2, 2025 · pp. 1–24 Read article
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Automatic Detection of Air Holes Inside The Esophagus in CT Images
Abstract: Automatic esophagus segmentation is a challenging problem. The wall of the esophagus consists of muscle tissue, which has a low contrast to vessels, other muscles and lymph nodes. Shape and appearance can vary a lot. It appears solid if it is empty, but it can also be filled with air, remains of orally given contrast agent, or both. Even for a human, it is often impossible to accurately delineate the …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 1, 2011 · pp. 24–28 Read article
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Upgrading Nutritive Value of Rice Straw: Processing, Supplementation, and Agronomic Innovations for Improved Utilization
Abstract: Rice straw, a major byproduct of rice production, holds significant potential as a livestock feed but is constrained by its high lignocellulosic content, low crude protein, and poor digestibility. Enhancing its nutritive value is imperative for sustainable livestock production. This study explores a range of innovative strategies aimed at improving rice straw’s digestibility and overall nutritional quality. Physical processing techniques, including chopping, grinding, soaking, and steam treatment, enhance its surface …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 1, 2026 · pp. 42–58 Read article
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Development of Software Packages for Computer Aided Design and Performance Analysis of Industrial Fractional Distillation Equipment
Abstract: This paper deals with improved CAD software packages that have been developed with the objective of improvising the existing conservative design of fractional distillation equipment. Since fractional distillation is extensively employed in petroleum refineries, distilleries and in a large number of chemical process industries, accurate design and optimised performance of these equipments are detrimental to the overall economy of these industries. Further, the efficient performance of the fractionators are dependent …
Published in Emerging Trends in Chemical Engineering · Vol. 2, Issue 3, 2015 · pp. 15–41 Read article
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A Review on Recent Trends and Challenges in Micromachining and Machinability of Ti-6Al-4V
Abstract: Based on several literature examinations from past decades, it is clearly observed that limited research has been done till date concerning to micromachining and had a partial understanding of it with focus on miniaturized parts. This article presents a complete comprehensive review on machining process at micro level with attention in drilling for work horse of titanium alloys. The Ti and its alloys are the most attractive materials due to …
Published in Trends in Mechanical Engineering & Technology · Vol. 9, Issue 1, 2019 · pp. 7–31 Read article
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Ant Colony Optimization in Cloud for Load Balancing
Abstract: There is an increase in the demand of cloud these days, as more and more people are looking for virtual storage of data rather than investing in physical storage. Cloud has many advantages like it focuses on maximizing the effectiveness of the shared resources. Cloud resources are shared by multiple users and these resources are dynamically allocated as per the demand. One of the major issues faced by cloud computing …
Published in Recent Trends in Parallel Computing · Vol. 1, Issue 1, 2014 · pp. 6–10 Read article
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Experimental and Computational Analysis of Parameters in Die-Sinking EDM Machine with AISI 316 Stainless Steel using TOPSIS
Abstract: This paper proposes an effective solution based on TOPSIS approach to determine the optimal process parameters in die sinking electrical discharge machining. Taguchi L9 orthogonal array is used to gather information regarding the process with less number of experimental runs. Experiments have been conducted using three process parameters such as peak current, gap voltage, pulse on time, with three levels are selected to optimize the multiple objectives. AISI 316 stainless …
Published in Trends in Mechanical Engineering & Technology · Vol. 6, Issue 3, 2016 · pp. 7–13 Read article