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336 articles for “genetic study”
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Molecular Docking Technique Assisted Discovery of Some Hydroxylated Chalcone Molecules as α-glucosidase Inhibitors
Abstract: The present study involved exploration of the inhibitory potential of some A-ring hydroxylated chalcone compounds against PDB ID: 2QMJ file (Maltase-glucoamylase in complex with acarbose) with the assistance of iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present study highlighted the immense potentials of several unexplored hydroxyl group (in ring-A) containing chalcones in successfully inhibiting the one of the most effective anti-hyperglycemic based enzymatic target α-glucosidase. The research has …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 1, 2019 · pp. 34–38 Read article
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Case Control Analysis on Neurodegeneration Disorders and Autism in Familial Context
Abstract: Neurodegenerative disorders such as Parkinson's and Alzheimer's co-occur with autism spectrum disorder (ASD), indicating shared genetic factors. Oxidative stress and inflammation play roles, with an elevated risk of Parkinson's and dementia in individuals with autism spectrum disorder. Antioxidant levels are linked to language and behaviour in autistic children. In the present study, a systematic review and meta-analysis was done following the PRISMA guidelines, reviewing English articles (2002- 2022) on familial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 2, 2023 · pp. 31–39 Read article
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Rust Resistance in Hexaploid Wheat (Triticum aestivum L. em Thell)
Abstract: Wheat (Triticum aestivum L. Em Thell) is the ‘golden grain’ of the cereals and plays a vital role in the contribution of global food. Wheat yield in India grew at a rate of 3.5% during 1940–82 and had a sudden decline during the next two decades to 2.9%. This decline can be attributed due to: (1) lack of improvement in the genetic yield potential, and (2) susceptibility to diseases. The …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 7, Issue 1, 2018 · pp. 11–21 Read article
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Genetic Algorithm: an Optimization Tool for Real World Problems
Abstract: AbstractThe main goal of this research work is to give the lesson on genetic algorithm with the help of evaluation concept of our environment. Genetic algorithm is a type of optimization algorithm, means it is used to find the optimal solution to a given computational problem that maximizes or minimizes a function. Genetic algorithms represent a branch of the field of study called evolutionary computation, in which they imitate the …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 9, Issue 3, 2019 · pp. 17–21 Read article
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Comparison of Models of Machine Learning and Hyperparameter Optimization Methods on Various Datasets
Abstract: The most likely phase in achieving powerful and robust machine learning models is probably the hyperparameter tuning step. The traditional exhaustive methods of search (grid search and others) ensure that the search space is covered, but are computationally inexpensive; random search is less expensive and can still miss good regions; and lastly, the modern model-based and population-based methods (Bayesian optimization, tree-structured Parzen estimator (TPE), genetic algorithms) are thought to provide …
Published in Recent Trends in Programming languages · Vol. 13, Issue 1, 2026 · pp. 35–42 Read article
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ANALYSIS AND DETECTION OF FINGERPRINT PATTERNS ACROSS THREE GENERATIONS IN FAMILIES OF THE VIDARBHA REGION POPULATION
Abstract: Fingerprint patterns are unique and reliable for identification. This study focuses on a comparative analysis to determine the inheritance of fingerprint patterns across three generations in families of the Vidarbha region population. The sample collection process for this comparative analysis involved working with 100 families. The study aims to gain insights into the hereditary aspects of fingerprint characteristics among three generations. The research methodology involves the collection of fingerprint samples …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 2, 2026 · pp. 10–18 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Zebra Fish Embryo Assay: A Wonderful Tool for Ecotoxicological Risk Assessment with Special Reference to Heavy Metals - An Overview
Abstract: In recent years, environmental pollution has become a pressing concern, prompting extensive research in aquatic ecotoxicology. With environmental degradation getting worse day by day, ecotoxicology research has gained a lot of attention. This area of study examines how biological communities in aquatic environments are affected by environmental contaminants. To unravel the toxicological mechanisms of these exogenous compounds, scientists turn to biological models. Several aquatic species, including zebrafish, toads, and big …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 56–70 Read article
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Bibliometric Analysis of Biochemistry, Genetics and Molecular Biology Research Output
Abstract: AbstractOne of the fundamental criteria to determine the research performance of any institute is its publication profile and more pertinently to say the quality of its published output. This study has tried to analyze the publications output and visibility of Biochemistry, Genetics and Molecular Biology in India. The data were collected from Web of Science database from last 20 years. It was found that the India observed progressive proclivity in …
Published in Journal of Advancements in Library Sciences · Vol. 2, Issue 2, 2015 · pp. 18–24 Read article
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Optimal Placement and Sizing of STATCOM for Loss Reduction and Voltage Profile Enhancement Using Genetic Algorithm
Abstract: Electric power distribution networks frequently experience significant power losses and voltage profile deterioration due to increasing load demand and inadequate reactive power compensation. This study investigates the enhancement of the Eleme distribution network in Rivers State through voltage upgrading and optimal deployment of a Static Synchronous Compensator (STATCOM). The existing network consists of a 5.56 km, 11 kV radial distribution system supplying seventeen distribution transformers with a cumulative load demand …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 2, 2026 · pp. 41–46 Read article
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Enhancing Puberty in Dairy Heifers: Targeted Management Practices For Sustainable Development.
Abstract: Early attainment of puberty in dairy heifers is critical for improving reproductive efficiency and ensuring sustainable dairy production systems. This study explores targeted management practices that can accelerate puberty onset, contributing to enhanced productivity and economic viability in dairy farming. Key factors influencing puberty in heifers include nutritional management, genetic potential, health care, environmental factors, and behavioral interventions. Adequate nutrient supply, especially energy and protein, along with balanced mineral and …
Published in Research & Reviews : Journal of Ecology · Vol. 14, Issue 2, 2025 · pp. 28–35 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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RsaI polymorphisms of ER-β and Idiopathic Male Infertility
Abstract: Purpose: Study on association between estrogen receptor gene polymorphism and male infertility has been interested, but highly specific genetic markers have been reported to be variable according to regions and nations. Herein we studied to figure out whether ERβ gene1082 G>A polymorphism could influence on sperm indices or not.Method: We dealt with 100 Korean patients with idiopathic male infertility diagnosed at our university hospital as a study group and 127 …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 3, 2022 · pp. 34–41 Read article
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Anxiety Due to Predator Odour as a Novel Tool for Evaluating Anxiolytic Drugs
Abstract: Development of anxiolytic drugs is impaired due to the absence of a proper and reliable method. We have used the ethological aspects of animals such as intent to mate and food avoidance to research an anxiolytic drug called Aforte. Our findings have clearly shown that the ethological parameters are more reliable than the conventional pharmacological test such as elevated plus maze test, rota rod test, forced swim test. The ethological …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 12–15 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Implementation and Development of Artificial Insemination in Dairy Cattle for Small Holder Farmers: The Case of Mirab Azernet Berbere Woreda, SNNPR, Ethiopia
Abstract: The study analyzed current status of implementation and development of artificial insemination in Mirab Azernet Berbere Woreda; believes and practices regarding artificial insemination in dairy cattle with respect to small holder farmers; and identifying constraints facing implementation and development of artificial insemination. The researcher combined qualitative and quantitative research methods with an explanatory and descriptive survey research methodology. Both primary and secondary data were gathered, probability and non-probability sampling strategies …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 12, Issue 2, 2023 · pp. 24–42 Read article
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Attitudes and Perceptions of the Research Scholars towards the Use of Anti-Plagiarism Software for Quality Research Output: A Study
Abstract: AbstractPresent study is an attempt to identify the attitudes and perceptions of the research scholars towards the use of anti plagiarism software for quality research output. Research is a process of conducting enquiry to create new knowledge. In the process of writing research papers and books, authors tend to copy existing content from other subjects without paying due acknowledgement to the original work. This results in violating copyright law and …
Published in Journal of Advancements in Library Sciences · Vol. 2, Issue 3, 2015 · pp. 7–17 Read article
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A Review on Clinical Aspects of Sickle Cell Anaemia
Abstract: Sickle cell anaemia is a genetic disorder in which there is a change in 6th position of Hb chain, i.e. replacement of glutamic acid by valine in the Hb chain. This disease was discovered in 1910 in United States by Dr. James B. Herrick. This disease was 1st affected to a young man named Walter Clement Noel from the island of Grenada, a dental student studying in Chicago. This article …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 2, 2017 · pp. 20–24 Read article
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A Survey of Genetic Algorithm Applications in Nuclear Fuel Management
Abstract: The prime aim of nuclear fuel management is to achieve higher fuel utilization without compromising safety during reactor operation. Nuclear fuel management optimization is a classical nuclear engineering problem, which has been studied for more than four decades and several techniques have been used for its solution. Genetic algorithm is one among the major global optimization techniques, used in the field of nuclear fuel management. Aim of this paper is …
Published in Journal of Nuclear Engineering & Technology · Vol. 4, Issue 1, 2014 · pp. 45–62 Read article
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Application of Genetic Algorithm in Resource Leveling and Allocation
Abstract: Resource leveling and allocation is one of the most important aspects in construction management. Critical path method and program evaluation review technique is frequently used for scheduling of construction projects. However, it is not capable of minimizing unwanted fluctuations in resource utilization profile. The basic idea of resource leveling is to minimize resource fluctuation. In addition to this, the paper uses the resource utilization period. This research paper presents an …
Published in Recent Trends in Civil Engineering & Technology · Vol. 5, Issue 3, 2015 · pp. 1–8 Read article