Search
217 articles for “Progressive Analysis”
-
Examining Connective Tissue Changes Across Various Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Histochemical Polymeric Investigation
Abstract: Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) represent a spectrum of potentially malignant disorders posing significant challenges in diagnosis and management. The tumor microenvironment, particularly alterations in the connective tissue, plays a crucial role in the progression of these lesions. This histochemical investigation comprised with embedded polymers aimed to examine connective tissue changes across various grades of oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 124–137 Read article
-
A Study of climate change and its impact on tourism
Abstract: Tourism is clearly linked to climate, as vacationers wish spending time in open-air and travel to delight in the sky or countryside. It is then amazing that the tourism works pays slight thoughtfulness to climate and climatic transformation. Numerous of investigations on tourism and climate change is, still, beginning to raise. Though it is a generally known statement that climate change can adversely effect on tourism sector and shake the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
-
Advancements in O-Glycosylation Techniques with Diverse Donor Molecules
Abstract: Since the early stages of carbohydrate chemistry, numerous researchers have employed alkynyl glycosyl donors as key reagents in glycosylation reactions. These donors have played a crucial role in facilitating the synthesis of glycosidic bonds, an essential aspect of carbohydrate-based compounds. Over time, various modifications and improvements have been introduced by different research groups to enhance the efficiency, selectivity, and sustainability of glycosylation processes. A major focus has been on designing …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 7–28 Read article
-
Liquid Biopsy in Solid Tumor: An Ultimate Source for Molecular Landscaping, Biomarker Discovery and Clinical Management
Abstract: Presently, work in the liquid biopsy field showed a great prospect utility in the diagnosis and stratification of cancer patients and furthermore personify an adaptive method for monitoring treatment response when compared to the tissue biopsy approach. Analysis of cell free DNA (cfDNA), circulating tumor cells (CTCs) and exosomes, all conjointly referred to as “liquid biopsies,” are not only a modality to monitor treatment efficacy, disease progression, and emerging therapy …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 3, 2019 · pp. 25–36 Read article
-
A Method of Mesh Deformation for Flow Analysis Around Oscillating Bodies
Abstract: In general, high-speed rotating machines are subjected to complex phenomena due to various reasons, such as increased noise and strong vibration due to dynamic unbalance, which affect the dynamic motion of rotating machines and are necessarily a problem to overcome. Therefore, it is necessary to have a mathematical model to simulate it, and a strong tool to solve the constructed model. Using fluid-structure coupling techniques, which are currently a powerful …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 2, 2025 · pp. 35–42 Read article
-
Transforming the Landscape of Advanced Dentistry: Incorporating Intelligence Augmentation (IA) and Artificial Intelligence (AI) to Propel Progress-A Narrative Review.
Abstract: Digitization is about to transform most sectors, and it is important to comprehend its role and socio-economic consequences. One of the infected sectors is dentistry and this article genericizes AI and IA in dentistry. It analyzes the advancement of AI and IA to supersede human capabilities using a comparative analysis of these technologies with current deployment. One of the challenges is to attain sufficient data input for AI and the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 2, 2025 · pp. 23–29 Read article
-
Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
-
Exploring the Relationship Between Disseminated Intravascular Coagulation and Waterhouse–Friderichsen Syndrome
Abstract: Waterhouse–Friderichsen syndrome was first identified as a distinct clinical entity by Little in 1901. He described four cases from his own observations and, after examining existing literature, identified eight additional cases that he considered previously unclassified. One case in his report may have involved purpura resulting from a different cause. The knowledge of this unusual disorder developed slowly from several significant clinical observations and case reports during the first two …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 45–49 Read article
-
An Introduction to Proteome Bioinformatics
Abstract: For basic and translational research, high-throughput approaches are essential. Recent improvements in proteomics techniques, for example, have allowed biomedical researchers to characterise the proteome of a variety of creatures. Proteome bioinformatics approaches and technologies have greatly aided this extraordinary progress. The study and use of informatics in the realm of proteomics is known as proteome bioinformatics. This chapter presents an overview of the computational strategies, methodologies, and techniques for bioinformatics …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 7–9 Read article
-
Ewing’s Sarcoma (ES): A Single Centre Retrospective Study
Abstract: The treatment of Ewing’s sarcoma (ES), which is thought to be derived from primitive mesenchymal cells, involves chemotherapy, surgery and radiotherapy. While there is ample data in the world literature showing drastic changes in outcome of this disease, prognosis in Indian patients is largely unknown due to dearth of studies in our setting. The objective of the present study was to study the clinical, pathologic, cytogenetic profile and outcome of …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 2, Issue 2, 2013 · pp. 1–7 Read article
-
Analysis of Cost and Schedule Performance of Residential Building Projects by EVM Technique
Abstract: Earned value management (EVM) is a project control technique which provides a quantitative measure of work performance by cost and schedule monitoring. It involves a crediting (earning) of budget as scheduled work is performed. The EVM technique is a proven method to evaluate work progress in order to identify schedule slippage and areas of budget overruns. Value earned for a given task is computed as budgeted cost of work performed …
Published in Journal of Construction Engineering, Technology & Management · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
-
Scientific Trajectories in Indian Virology: Innovations, Institutions, and Impact
Abstract: India's substantial research on epidemiology, virology, and public health measures has helped the world understand viral infections better. This article gives an overview of virus research in India, starting with early studies on arboviruses and enteroviruses and going all the way up to current studies on new and re-emerging pathogens including SARS-CoV-2, Nipah, and Zika viruses. Over the decades, India has built a rich legacy in virus research through pioneering …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 11–20 Read article
-
Molecular Docking, QSAR Modeling, and ADMET Evaluation of Novel Pyrazolo-Pyrimidine Derivatives as Potential CDK-2 Inhibitors for Cancer Therapy
Abstract: Cyclin-dependent kinase-2 (CDK-2) is an essential regulator in cell cycle progression and is an important therapeutic target in cancer drug development. In the present study, an integrated computational approach involving molecular docking studies, QSAR modeling, ADMET prediction, and artificial intelligence-based analysis was used to identify pyrazolo-pyrimidine derivatives as potential CDK-2 inhibitors. Based on the molecular docking results, it was found that selected compounds exhibited high binding affinity towards the ATP …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
-
Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
-
Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
-
To Examine of Novel Biosensor Strategies for Analysis of Meals Contaminants and Medical Analytes
Abstract: AbstractGeneral wellbeing standard relies upon the nature of diet items. Aside from valuable constituents, sustenance items additionally contain contaminants that are lethal in nature and can cause contaminations and maladies. Characterizing human presentation to different contaminants like chemicals (urea), biochemical (anti-infection agents), or organic (microorganisms) is a gigantic assignment. Ordinary systems are not equipped for giving high-throughput and touchy location of these contaminants, particularly in milk, water and clinical analysts. …
Published in Recent Trends in Sensor Research & Technology · Vol. 5, Issue 1, 2018 · pp. 31–39 Read article
-
BUCKLING ANALYSIS OF COMPOSITE CYLINDRICAL SHELL STRUCTURE USING FINITE ELEMENT ANALYSIS
Abstract: When designing cylindrical shells one should consider not only the strength problem in service, but also the buckling problem. Cylindrical shells such as thin-walled structures are susceptible to buckling when subjected to static and dynamic stresses. The vessels are exposed to dynamic sea conditions depending on their usage. The functional failure of a pressurized composite vessel or a composite pipe in the form of leakage or weeping of the contained …
Published in Journal of Polymer & Composites · Vol. 7, Issue 2, 2019 · pp. 32–36 Read article
-
Influence of Carbonyl Iron Particle Loading on the Dimensional and Rheological Properties of 4D-Printed TPU-Based Magnetorheological Elastomers
Abstract: The advancement of 4D printing technologies has created new opportunities for fabricating smart materials with tunable properties, including magnetorheological elastomers (MREs). This study investigates the fabrication and characterization of thermoplastic polyurethane (TPU)-based MREs with varying carbonyl iron particle (CIP) loadings (10–50 wt.%) using the fused filament fabrication (FFF) method. MRE filaments were produced through a solvent-assisted mixing and extrusion process, ensuring consistent diameters within 1.75 ± 0.10 mm. Test specimens …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 127–138 Read article
-
Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
-
Experimental and Numerical Investigation of Corrosion-Induced Failures in Copper-Tin Alloy (Cu-Sn) and Aluminum-Magnesium Alloy (Al-Mg) Connectors: A Stress–Corrosion Coupling Analysis
Abstract: The utilization of an integrated experimental and finite element modelling (FEM) methodology, this study investigates the degradation and failure mechanisms in polymer composite electrical connectors exposed to aggressive environmental conditions. Epoxy- and polyamide-based composites, reinforced with carbon and glass fibers, were subjected to accelerated salt spray and humidity–temperature cycles to simulate prolonged outdoor exposure. Electrochemical and environmental aging experiments revealed that chloride ions and moisture ingress were responsible for matrix …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 366–379 Read article