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1074 articles for “PHA”
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Harnessing Polymer Chemistry for Pharmaceutical Technology
Abstract: Polymer chemistry has emerged as a cornerstone of modern pharmaceutical technology, offering unprecedented control over drug formulation, delivery, and therapeutic performance. This review highlights the pivotal role of polymers—both synthetic and natural—in revolutionizing drug delivery systems across various routes, including oral, parenteral, transdermal, ocular, nasal, and pulmonary administration. Special emphasis is placed on the structural and functional versatility of polymers, which allows for tailored drug release profiles, enhanced bioavailability, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1–6 Read article
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Exploration of Advanced Phase Change Materials for Thermal Energy Storage in Renewable Energy Systems: An Overview
Abstract: Phase Change Materials (PCMs) are increasingly vital for improving thermal energy storage (TES) systems. Their ability to absorb and release heat efficiently makes them ideal for renewable energy applications, enhancing energy efficiency, reducing waste, and supporting sustainable energy solutions across various sectors like solar power and building temperature regulation. Their ability to store and release latent heat during phase transitions makes them ideal for addressing the intermittency of renewable energy …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 10–14 Read article
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A Systematic Review of Impurity Profiling and Stability Studies in Pharmaceutical Drug Substances
Abstract: Ensuring the safety, efficacy, and quality of pharmaceutical goods is essential in the Indian pharmaceutical market, which is a global centre for generic drugs. Stability studies and impurity profiling are two fundamental activities that ensure this quality during the whole lifespan of a medicine. The effect of environmental variables such as temperature, humidity, and light on the quality of a drug substance over time is demonstrated by stability studies. The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 81–88 Read article
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AI in Pharmacy Automation: A Review of Innovations in Robotics, Their Ethical Implications, and Impact on Workflow and Workforce
Abstract: The pharmacy profession has witnessed a paradigm shift with the integration of robotics and artificial intelligence (AI) in automation. Traditional practices that relied heavily on manual dispensing, paper documentation, and technician labor are now being augmented or replaced by robotic dispensing systems, sterile compounding machines, and predictive AI algorithms. These innovations enhance safety, improve efficiency, and reduce errors, while also raising complex ethical questions related to workforce displacement, liability, and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 01–07 Read article
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Pharmacological Comparison of Turmeric and Non-Steroidal Anti-Inflammatory Drugs in Pain Relief
Abstract: Pain is one of the most frequently encountered clinical symptoms affecting millions globally and is typically treated pharmacologically with nonsteroidal anti-inflammatory drugs (NSAIDs). However, long-term use of NSAIDs is associated with adverse effects such as gastrointestinal, renal, and cardiovascular issues. In recent years, turmeric and its main active compound, curcumin, have received considerable attention for their reported anti-inflammatory, analgesic, and antioxidant properties as natural therapeutic options. This review seeks to …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 19–28 Read article
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Role of Pharmaceutical Software in Vaccine Development and Manufacturing Process Optimization
Abstract: Vaccine development and manufacturing have become increasingly complex due to the emergence of diverse vaccine platforms, stringent regulatory expectations, and global demand for safe and effective immunization. Across the vaccine lifecycle – from antigen design and preclinical evaluation to large‑scale manufacturing and post‑marketing surveillance – pharmaceutical software now plays a central role in handling data, optimizing processes, and ensuring regulatory compliance. Software tools support in silico antigen and epitope design, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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IoT-Based Real-Time Monitoring System for Temperature and Humidity Control in Pharmaceutical Manufacturing
Abstract: Environmental conditions, especially temperature and humidity, play a vital role in pharmaceutical manufacturing processes. Even minor fluctuations in these parameters can significantly influence the stability, potency, and overall effectiveness of drug formulations. In many cases, uncontrolled environmental variations may lead to chemical degradation, reduced shelf life, contamination risks, and substantial financial losses for manufacturers. Therefore, maintaining precise and consistent environmental conditions is essential to ensure product quality, regulatory compliance, and …
Published in International Journal of Mobile Computing Technology · Vol. 4, Issue 1, 2026 · pp. 32–37 Read article
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Digitally Tunable Dual-Phase Polymer–PCM Composites for IoT-Based Adaptive Thermal Management in Smart Buildings
Abstract: This study presents the design and development of digitally tunable dual-phase polymer–phase change material (PCM) composites for advanced thermal management in smart building applications. The composite is based on a hybrid polymer matrix comprising thermoplastic polyurethane (TPU) and a crosslinked polyvinyl alcohol (PVA) gel, reinforced with paraffin microencapsulated PCM and hydrated salt PCM to achieve multi-stage thermal energy storage. The polymer composite architecture enables enhanced structural integrity, high encapsulation efficiency …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 147–157 Read article
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Pharmacognostical and Phytochemical Study ofAdhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: To carry out pharmacognostical and phytochemical studies on each part of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: The root, leaf, stem, flower and fruits of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, elemental analysis, and preliminary …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
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Development and validation of a method for simulataneous determination of tenovifir disoproxil fumarate emtriculabine and isonized in bulk and pharmaceutical dosage form using RP-HPLC with relevance to toxicological aspects
Abstract: Hence, proposed analytical methods are simple, novel, economical, rapid, sensitive, reproducible and accurate for the Simultaneous estimation of Tenofovir Disoproxil Fumarate, Emtricitabine and Isoniazid in Bulk and Phamaceutical dosage form by using RP- HPLC. This Method gives reliable assay results with short analysis time using mobile phase of Acetonitrile : 0.02M Potassium Dihydrogen Orthophosphate: water (pH 5.3) in the ratio of 60: 25: 15 respectively. Retention time was found to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 17–25 Read article
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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A Comprehensive Review of Ayurvedic Pharmaceutics in Charaka Samhita W.S.R to Chikitsasthana.
Abstract: Charaka Samhita provides insightful information on the holistic approach to well-being by addressing every facet of health, from illness management to preventive measures. It is organized into eight Sthana, and is filled with information on anatomy, physiology, disease etiology, diagnosis, treatment, and health maintenance principles. The term "Charakastu Chikitsite" denotes that Charaka Samhita is the greatest treatise on Ayurvedic therapeutics. Numerous subjects related to diagnosis, treatment planning, and disease management …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 14–25 Read article
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Flora-Vision: A Quality Assurance System For The Pharmaceutical Industry
Abstract: In contemporary pharmaceutical production, the persistent challenges of manual labor, human error, and contamination risks pose significant obstacles to efficiency and product quality. Particularly in sectors such as Ayurvedic products, cosmetics, and medicines, the need for innovation is pressing. Revolution in production process can be addressed by introducing innovative solutions and thereby challenges could be overcome. Through the utilization of advanced technology, the proposed system streamlines sample management and quality …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 53–60 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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Green Analytical Chemistry in Pharmaceuticals: Pathways to Sustainability and Compliance
Abstract: This review paper explores the integration of green analytical chemistry (GAC) in the pharmaceutical industry as a pathway to EU compliance and environmental sustainability. The review highlights a range of studies that focus on the application of green solvents, green extraction methods, biocatalysts, and energy-efficient techniques. Key findings suggest that employ eco-friendly solvents, such as ethanol and water and methods, like ultrasound-assisted extraction (UAE) and supercritical fluid extraction (SFE), significantly …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 7–12 Read article
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Quantum Mechanics: Revolutionizing Pharmaceutical Sciences
Abstract: Quantum physics and pharmacy have generally been regarded as distinct areas—one investigates the microlevel behavior of non-living matter while the other concentrates on intricate biological systems. Nevertheless, progress in life sciences has increasingly depended on molecular-level insights, whereas quantum physics has advanced beyond basic principles to impact real-world uses. This intersection provides new opportunities for, pharmacy. Quantum entanglement, which allows for instantaneous relationships between particles, can be utilized for secure …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 72–77 Read article
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Enhancing Thermal and Mechanical Performance of Polymer-Based Phase Change Materials with Graphite Nanoplatelets: A High-Efficiency Approach for Energy Storage Applications
Abstract: This study explores the performance enhancement and characterization of polymer-based phase change material (PCM) composites reinforced with graphite nanoplatelets (GNPs) for thermal management applications. The integration of GNPs significantly improved thermal conductivity, which increased from 0.38 W/m·K in pure PCM to 2.60 W/m·K with 10 wt% GNPs, marking a 580% improvement. Differential Scanning Calorimetry (DSC) analysis revealed a reduction in latent heat capacity from 180 J/g to 150 J/g—approximately 16.7%—attributed …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 150–162 Read article