Search
308 articles for “Method validation”
-
Recent Trends in Fluid Mechanics with Emphasis on Aeroacoustics and Flow-Induced Noise Control
Abstract: Fluid mechanics continues to evolve rapidly due to increasing demands in aerospace, automotive, energy, and environmental engineering applications. Recent trends in this field highlight significant advancements in both theoretical understanding and practical implementations, particularly in complex flow phenomena. Among these, aeroacoustics and flow-induced noise control have emerged as critical research areas due to their direct impact on system performance, efficiency, and environmental sustainability. Aeroacoustics deals with the generation, propagation, and …
Published in Recent Trends in Fluid Mechanics · Vol. 13, Issue 1, 2026 · pp. 32–38 Read article
-
Experimental Investigation and Optimization of Machining Parameters for Al6351 Alloy Using a Modified Taguchi Approach
Abstract: Machining processes encompass both conventional and non-conventional techniques and optimizing machining parameters is crucial for achieving high-quality outcomes. However, simplifying these processes remains a significant challenge. This study focuses on determining the optimal machining parameters—cutting speed, feed rate, and depth-of-cut to enhance performance characteristics in Al6351 alloy plates. The parameters evaluated include surface roughness (Ra), material removal rate (MRR), resultant forces (RF), and temperature at the tool- workpiece interface (Temp). …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1463–1481 Read article
-
Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
-
SYNTHESIS, CHARACTERIZATION AND BIOMEDICAL APPLICATIONS OF A SILVER NANOPARTICLE-COATED CHITOSAN–FUCOIDAN POLYMER NANOCOMPOSITE LOADED WITH PERSEA AMERICANA LEAF EXTRACT
Abstract: Consuming a natural composite of Persea americana (Avocado) leaf extract and a chitosan and fucoidan form a biodegradable biopolymer matrix–polymer nanocomposite with biomedical applications, this study explored a potential therapeutic method. GC-MS and UV spectroscopy were used to describe the aqueous leaf extract, which was verified by phytochemical screening to contain flavonoids, tannins, phenols, terpenoids, and alkaloids. The chitosan–fucoidan biodegradable polymer matrix served as a biocompatible stabilizing and encapsulating carrier …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
-
Mechanical Strength Prediction of Nano-Silica Concrete Composites Using Machine Learning Techniques
Abstract: Nano-silica, or nanosilica, refers to silicon dioxide nanoparticles, which are a kind of silica (SiO₂) with diameters that often fall below 100 nanometers. This nanomaterial has attracted considerable attention because of its distinctive characteristics and diverse array of uses, notably in augmenting the performance of materials such as concrete. The integration of nanoparticles with cementitious matrix in nano-silica concrete offers a viable approach to improving the mechanical characteristics and longevity …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 963–973 Read article
-
Nano Positioning for Large Scanning Range for XY Mechanism
Abstract: In this study, an XY flexure stage that provides a variety of motion options while reducing incorrect motions is designed and assessed. In the flexure design, the double parallelogram flexure modules are positioned methodically and symmetrically. The performance of the flexure stage is assessed using finite element analysis, and experimental testing is performed to validate the findings. The built-in prototype of the flexure stage has dimensions of 350 mm x …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 1, 2025 · pp. 30–35 Read article
-
Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
-
Self Healing Material: An Introduction
Abstract: Self-healing materials have emerged as a transformative innovation for sustainable infrastructure and advanced applications such as wearable electronics and smart transportation systems. These materials possess the intrinsic ability to repair damage autonomously or with minimal external intervention, thereby extending service life and reducing maintenance costs. Inspired by biological systems, self-healing mechanisms are broadly classified into extrinsic approaches, such as microcapsule and vascular networks based healing, and intrinsic mechanisms involving reversible …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 604–611 Read article
-
Improvement of Geometric Tolerances and Mechanical Properties of Aluminum Hybrid Metal Matrix Composites
Abstract: In the field of metal matrix composite materials, there has been a generous thrust towards the development of electrical discharge machining (EDM). In this study, stir casted aluminum hybrid metal matrix composites were successfully machined using EDM by analyzing the input process parameters namely, pulse-on time, peak current, and gap voltage using L27 orthogonal array. The ideal conditions for various output responses such as material removal rate, circularity, and radial …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1583–1592 Read article
-
Machine Learning Assisted Design and Analysis of Polymer Composite Materials for Sustainable Renewable Energy Systems
Abstract: Accurate prediction and optimization of polymer composite properties is of paramount importance in the design of these lightweight, durable, and sustainable materials within renewable energy technologies. This work will provide a holistic machine learning-assisted framework that unites materials informatics with domain-specific features and state-of-the-art ML methodologies in the prediction of the mechanical properties of polymer composites, such as tensile strength. This includes embedding several ensemble models, including Random Forest and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 391–402 Read article
-
The Awareness–Behaviour Paradox: Media Literacy and Social Media Risk Behaviour Among Nigerian Undergraduates
Abstract: Background: The proliferation of internet-capable devices and social media platforms has created an intricate web of risks for Nigerian undergraduates, including cyberbullying, addiction, misinformation, and exposure to indecent content. While media literacy has been widely proposed in Western scholarship as a sustainable intervention for responsible online behaviour, its protective mechanisms remain insufficiently understood in non-Western contexts, particularly with respect to the psychological pathways through which literacy operates. Objectives: This study …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 121–126 Read article
-
A Review on Parametric Optimization of WEDM Technique for OHNS Steel
Abstract: In this study, the Wire Electrical Discharge Machining (WEDM) process for OHNS (Oil Hardened Non-Shrinking) steel, a high-performance material frequently used in the production of dies, punches, and precision tooling components, is optimized parametrically and validated experimentally. A continuously moving wire electrode and a sequence of electrical discharges are used in WEDM, a non-traditional machining method, to erode material and produce intricate and precise profiles, particularly in materials that are …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 29–35 Read article
-
Fractal-Entropy Guided Adaptive Signal Reconstruction for Non-Stationary Biomedical and Communication Systems
Abstract: This paper presents a novel Fractal-Entropy Guided Adaptive Signal Reconstruction (FEG- ASR) framework designed for accurate processing of non-stationary signals in biomedical and communication systems. The proposed approach integrates fractal dimension analysis with entropy- based feature evaluation to capture the intrinsic complexity and irregularity of time-varying signals. By dynamically adapting reconstruction parameters based on fractal-entropy measures, the method effectively separates noise from meaningful signal components while preserving critical information. The …
Published in Current Trends in Signal Processing · Vol. 16, Issue 1, 2026 Read article
-
Artificial Neural Network Modelling to Optimize Micro-Drilling Parameters of ECDM of Developed Novel Zn/(Ag+Fe)-MMC
Abstract: Several engineering fields have increased their use of metal matrix composites (MMCs) in the past few years. Due to the increase in composites, the demand for accurate machining has also become important. Specifically, pertaining to biomaterial applications, accuracy factor with desired surface finish is critical. While the near-net shape manufacturing process has advanced, MMCs frequently require post-mould machining to achieve surface quality, and dimensional tolerances. In the present study, a …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 01–13 Read article
-
Presence of a Bulk Viscous Universe within f(R, T) Gravity
Abstract: This paper offers a comprehensive analysis of a bulk viscous universe in the context of f(R, T) gravity, where (R) signifies the Ricci scalar and (T) represents the trace of the energy-momentum tensor. The primary objective of our work is to get explicit solutions to the modified field equations by using a power-law scale factor representation. With this method, we have obtained functions of cosmic time and redshift for the …
Published in International Journal of Universe · Vol. 1, Issue 1, 2025 Read article
-
Role of Crispr-Cas9 in Plants
Abstract: The innovative CRISPR Cas9 system has emerged as a game changing genetic engineering tool in years offering levels of precision, efficiency and flexibility in editing the genomes of various organisms, including plants. This summary aims to provide an examination of the role of CRISPR Cas9, in modifying plant genomes highlighting its benefits, drawbacks and possible uses. Thanks to its versatility and user-friendly nature CRISPR Cas9 technology has expedited studies in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 1–10 Read article
-
A Factorial Investigation of Hyperparameter Tuning Strategies for Lasso- Based Genomic Prediction
Abstract: In an earlier comparative study of machine-learning methods for genomic prediction of wheat grain yield, we reported a counter-intuitive result: automated nested-cross-validation tuning of the Lasso regularization penalty reduced mean predictive ability relative to a fixed, arbitrarily chosen penalty (mean Pearson r falling from 0.408 to 0.349 across four environments), the opposite of the expected effect of hyperparameter tuning. We hypothesized two possible explanations at the time — high-variance penalty …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
-
Generative AI-Based Inverse Design of Sustainable Biodegradable Polymers with Target Mechanical and Thermal Properties
Abstract: The escalating global plastic pollution crisis has intensified the urgent need for sustainable biodegradable polymer alternatives that can match or exceed the performance of conventional petroleum-based plastics while minimizing environmental impact. However, traditional polymer discovery approaches are severely constrained by high experimental costs, protracted development cycles spanning years, and fundamental inability to simultaneously optimize multiple conflicting material properties such as mechanical strength, thermal stability, and degradation kinetics. This study presents …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
-
Relationship Between Mental Health, Competitive Aggression and Anger Rumination with Regard to the Role of Mental Health of Martial Arts Athletes in Gilan Province
Abstract: Due to the phenomenon of championship in sports, athletes are always very thirsty to achieve the championship and go on the podium, and this factor can cause negative behaviors by athletes, one of which is competitive aggression. Therefore, the main purpose of this study is to investigate the relationship between mental health, competitive aggression and anger rumination with regard to the role of mental health of martial artists in Gilan …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 1–10 Read article
-
Early Disease Detection Using Artificial Intelligence
Abstract: Growth in artificial intelligence and machine learning now make it possible for the healthcare sector to be totally transformed by a new chapter, particularly in the era of medical image analysis. This study focuses on harnessing these advancements to develop a sophisticated model for early disease detection across diverse medical domains, majorly in skin disease. By integrating diverse datasets and leveraging advanced algorithms, our methodology aims to identify subtle disease …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 · pp. 11–19 Read article