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1916 articles for “MMP-2” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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The Role of Rubella Virus Infection among Women with Spontaneous Abortion in Al-Najaf Governorate
Abstract: Rubella virus could cause a spectrum of birth defects known as Congenital Rubella Syndrome (CRS) if the infection occurs within the first or second trimester of pregnancy. Repeated miscarriage is defined as a condition with two or more consecutive abortions before the 20–25 weeks of gestation. Rubella remains to be a severe public health problem in developing countries. Recurrent miscarriage is a multi-factorial disease, which occurs in approximately 1%–2% of …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 · pp. 1–6 Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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A Comprehensive Review on COVID-19 Evolution and Development
Abstract: The emerging pandemic causing flu-like symptoms in patients is caused by the novel Coronavirus that was previously called 2019-nCoV. The mutated gene of SARS-CoV was transformed to SARS-CoV-2 in animals and further transmitted to humans in the month of December 2019 in Wuhan city of China. Eventually, the novel coronavirus spread all around the globe as a highly contagious disease. COVID-19 (the illness caused by coronavirus) has affected 213 countries …
Published in Research and Reviews : A Journal of Life Sciences Read article
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Assessment of Groundwater Quality in Rumuodara, Rivers State, Nigeria
Abstract: The assessment of groundwater quality from selected borehole in Rumuodara, Rivers State, Nigeria was evaluated. The results of the physicochemical parameters revealed that pH ranged from 6.57-6.60, temperature: 26.10-28.54oC, turbidity: 1.57-2.96NTU, conductivity: 41.24-68.44 μS/cm, salinity: 26.10-50.37mg/l, total dissolved solid: 18.9-63.14mg/l, total hardness: 38.21-48.30mg/l, alkalinity: 55.30-70.17mg/l, chloride: 28.40-75.14mg/l, sulphate: 21.50-30.60mg/l, nitrate: 1.50-3.04mg/l, phosphate: 59.24-65.40mg/l, calcium: 37.81-45.27mg/l, Iron: 0.133-0.190mg/l, sodium: 16.70- 21.13mg/l, copper: 0.22–0.50mg/l, total suspended solid: 2.94-3.60mg/l, Lead: < 0.01mg/l-2.27mg/l, zinc: …
Published in Research & Reviews : Journal of Ecology Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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Rise of Python: Analyzing Its Dominance in 2023 Programming Trends
Abstract: The study is on how Python rose as a leading programming language in 2023 and what are the top reasons of this ubiquitous utilization among industries. The Python programming language has been a go-to choice for both beginners and developers alike, courtesy of its versatility in working over various domains like Data Science, Machine Learning Web Development Automation etc. By having a vast library and framework ecosystem, supported by popular …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 2, 2024 · pp. 43–47 Read article
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A Research Study on Navigating Medication Risks Through MFRS (Medication Fall Risk Score and Evaluation Tool) and DART (Drug Associated Risk Tool) Among Patients with Polypharmacy
Abstract: Background information: The advancements in medical science continue, but the safety of medication usage is still a question mark and has become a crucial area for researchers to focus on. In the need of the above, various scoring systems and tools have been developed in pharmacy practice research. Prior to the present work, we did a systematic review and meta-analysis and identified two such tools: the medication fall risk score …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 1–13 Read article
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Renewable Solar Energy Prediction in India : 2025-2030
Abstract: As India endeavors to realize its objective of achieving 500 GW of renewable energy capacity by the year 2030, the precise forecasting of solar power generation is rendered increasingly essential. This scholarly article conducts a comprehensive review of the utilization of machine learning (ML) methodologies in the prediction of solar energy across diverse Indian states, underscoring their potential to address the complexities associated with the variability of solar irradiance. Conventional …
Published in Journal of Power Electronics and Power Systems · Vol. 14, Issue 3, 2024 · pp. 41–46 Read article
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Design of a Water-Cooling System for the Inside Roof of 20t Electric Arc Furnace for Oxygen Blow Decarburization Using CFD Analysis
Abstract: An electric arc furnace (EAF) roof usually works at high temperature for a long time, undergoes not only heat radiations from electric arc, molten metal, and lining of high temperature, but also is washed and affected by chemical erosion due to high temperature and gas flow. In addition, it might be eroded by slag with high temperature. In， inside roof of EAF is more severely affected by heat load than …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 11–17 Read article
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Comparative Efficacy of Hybrid Capture 2 and Real-Time PCR in Detecting High-Risk HPV Genotypes for Cervical Cancer Screening
Abstract: Human papillomavirus (HPV) infection is a leading cause of cervical cancer, making early detection critical for effective prevention and treatment. Among the diagnostic methods available, Hybrid Capture 2 (HC2) and Real-Time Polymerase Chain Reaction (PCR) are widely used for detecting high-risk HPV genotypes, particularly HPV 16 and 18, which account for the majority of cervical cancer cases. This review aims to compare the efficacy of HC2 and Real-Time PCR in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 13–17 Read article
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Nanocomposites of Polyethylene-Closite 20A: Preparation and Characteristics
Abstract: Low-density polyethylene/closite 20A nanocomposites with different organoclay contents were made in the current study by a melt mixing technique with two different compatibilizers of varying contents: low molecular weight oxidized polyethylene and low molecular weight trimethoxysilyl modified polybutadiene. The inclusion of compatibilizers and concentrations of organoclay were analyzed in relation to the mechanical and thermal properties of the nanocomposites. The dispersibility of the silicate clay in the nanocomposites was investigated …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 01–12 Read article
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Review on Clinical Safety and Efficacy of Giant Calotropis in the 21st Century
Abstract: Calotropis gigantea, a highly valued plant in traditional Indian pharmacology, has emerged as a promising candidate for therapeutic innovation. This review delves into the clinical safety and efficacy of C. gigantea in the 21st century, examining its historical use, phytochemical composition, and pharmacological properties. While traditional medicine has long utilized C. gigantea for various ailments, modern research has sought to validate these claims through scientific investigation. This review critically analyzes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 26–34 Read article
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Knowledge and awareness of final years dental and medical students towards management. and clinical outcomes of maxillary sinus squamous cell carcinoma 2021
Abstract: Background: - study aimed to assess dental and medical students' knowledge on managing and clinical outcomes of maxillary sinus squamous cell carcinoma, a preventable and treatable cancer, and to address delays in referral and treatment.. objective: -To assess a knowledge and awareness of management and clinical outcomes of maxillary sinus squamous cell carcinoma among final years dental students and medical students at university of Khartoum Materials and Methods: A cross-sectional …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 10–17 Read article
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Unveiling Empowerment: Evaluating Entrepreneurial Effectiveness of Self-Help Groups in Murshidabad and South 24 Pargana
Abstract: Self-help groups (SHGs) have played an essential role in the socio-economic upliftment of society, especially in West Bengal over the last decades. Analytically discussing gender dimensions in the SHGs, this paper scrutinizes the efficiency of the two districts, namely, Murshidabad and South 24 Parganas considering certain parameters. Based on the analysis of the parameters of the empowerment indicators and socio-economic effects of the SHGs, the paper explains to what extent …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 2, 2024 · pp. 23–33 Read article
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Exploring the Influence of Machining Parameters on Geometric Form and Orientation Controls (23 Design)
Abstract: This work explores the influence of machining parameters using on geometric form controls flatness and straightness as well as orientation control parallelism using an aluminum 6061 workpiece. Due to its good strength, machinability and cost- effectiveness, aluminum 6061 is widely used. In this experimental work, full factorial design is used and each factor has two levels. The response parameters chosen include flatness, straightness, and parallelism, which govern the form and …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 1, 2025 · pp. 10–16 Read article
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3D Printing in the 21st Century: A Critical Review of Advances and Impacts Across Sectors
Abstract: 3D printing, or additive manufacturing, has become a pivotal technology in the 21st century, reshaping a variety of industries. This review critically examines the technological advancements that have driven the widespread adoption of 3D printing, including innovations in printing materials, precision, and speed. In sectors like healthcare, aerospace, automotive, and consumer goods, 3D printing has revolutionized product development, enabling rapid prototyping, customizations, and more efficient manufacturing processes. In healthcare, for …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 18–24 Read article
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Curbing Speculation vs. Market Participation: A Study of SEBI’s 2024 Derivatives Measures
Abstract: The derivative market has become a cornerstone of India’s financial ecosystem, complementing the traditional stock market by enabling risk management, price discovery, and liquidity enhancement. However, with the rapid growth of this segment, concerns over speculative activities have prompted regulatory intervention. On October 1, 2024, the Securities and Exchange Board of India (SEBI) introduced significant reforms aimed at curbing speculation, protecting retail investors, and fostering market stability. While these changes …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 2, 2025 · pp. 28–43 Read article
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Selection of Ionic Liquids for the Design of Separation Processes of CO₂ + H₂S Mixed Waste Gases with Different Compositions
Abstract: The waste gas from chemical plants contains H 2 S gas and a large amount of CO 2 gas. These flue gases can be treated in various ways, and in this paper, the mixed flue gas CO 2 +H 2 S was treated by using ionic liquids (IL) as an absorbent. Ionic liquids are considered green solvents with remarkable good properties. In particular, it is known as a very effective …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 44–58 Read article