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234 articles for “GANs”
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Synthesis of Biofuel from Castor Oil Using Novel Catalysts
Abstract: An essential step in improving biofuels, especially those made from biomass, is hydrodeoxygenation (HDO). HDO's primary goal is to eliminate oxygen atoms from the biofuel feedstock in the form of water, which enhances the fuel's energy density, stability, and compatibility with current fuel.This study uses a large surface area catalyst to investigate the hydrodeoxygenation (HDOx) activity of non-edible oils. In addition to other supports including H-USY and MCM-41, large surface …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 226–237 Read article
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Solid Rocket Motor Case: A Review of Existing Design and Composite Material Criteria
Abstract: Solid propulsion systems are an integral part of inaugural vehicles for many space agencies because of their relatively simple design and high reliability. The solid propulsion rocket motor case design, including the material used for fabrication, is an important aspect as it affects the solid rocket motor's performance, reliability, and safety. In this abstract, an attempt has been made to review the most commonly used materials in the manufacture of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 224–232 Read article
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Impact of Chemical Conditioning on the Mechanical Performance of Pine Fibre-Reinforced Composites
Abstract: The study examines the effects of treatments like alkaline, silane, and acetylation on enhancing the mechanical strength and reducing water absorption in pine fiber-reinforced composites. Natural fibres, while eco-friendly and sustainable, present challenges in fibre-matrix adhesion due to their hydrophilic nature, impacting composite performance. Chemical treatments were employed to modify fibre surface characteristics, enhance interfacial bonding, and thereby improve mechanical properties. Silane-treated composites exhibited the highest tensile and flexural strengths, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 140–150 Read article
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A Study to Evaluate the Effectiveness of a Computer-assisted Teaching Program on Knowledge About the Distribution and Use of Iron and Folic Acid Tablets During the Antenatal Period Among Primigravida Mothers in Selected Villages of Holenarasipura Taluk, Karnataka
Abstract: Pregnancy is a critical period in a mother’s life, and proper knowledge about managing pregnancy is essential for maternal and fetal health. This study aimed to evaluate the effectiveness of a computer-assisted teaching program in improving knowledge about the distribution and use of iron and folic acid tablets among primigravida mothers in selected villages of Holenarasipura taluk. A one-group pre-test and post-test pre-experimental design was employed, using non-probability convenience sampling …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 28–40 Read article
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Power Quality Improvement in Grid-Connected PV Systems using TCSC
Abstract: Power quality issues such as voltage sags, swells, and harmonic distortions pose significant challenges to the stability and efficiency of grid-connected systems. This study presents a simulation and analysis of a Thyristor-Controlled Series Capacitor (TCSC) for mitigating voltage sags and swells, thereby enhancing overall power quality. A grid-connected photovoltaic (PV) system integrated with a TCSC is modelled and simulated using MATLAB/Simulink to evaluate its performance under diverse operating conditions. The …
Published in Trends in Electrical Engineering · Vol. 14, Issue 3, 2024 Read article
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Targeting Homogentisate Dioxygenase Dysfunction in Alkaptonuria: Investigating Curcuma longa’s Therapeutic Potential
Abstract: Objectives: Alkaptonuria is known to have a faulty gene HGO in the metabolic process. In the present research work, the focus is towards investigating the therapeutic capabilities of the Curcuma longa upon the faulty Homogentisate dioxygenase gene using ligand-protein binding, which would assist in the corrective tyrosine metabolism. Methods: This study is based on the computational approach using different phytochemicals for evaluation of the potency against the abnormal Homogentisate dioxygenase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 1–11 Read article
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Use of AI Tools to Create New Drugs
Abstract: The emergence of artificial intelligence in pharmaceutical research [in drug discovery] is a revolution in pharmaceutical research, often combining computational methods with traditional research methods to solve problems. This review article describes various applications of artificial intelligence at various stages of drug development and highlights significant advances and approaches. He explores the critical role of intelligence in drug design, polypharmacology, drug synthesis, drug repurposing, and prediction of drug properties, such …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 22–49 Read article
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Dasatinib Induced Pulmonary Hypertension
Abstract: Dasatinib (Das) is a second-generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML) in patients who are resistant or intolerant to imatinib, as well as in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) patients. Dasatinib-induced pulmonary arterial hypertension (PAH) is a known but rare adverse effect of dasatinib and is grouped under Group-1 PAH. The mechanism of PAH development is not fully known, but …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 92–95 Read article
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Review: The Future of Over-the-Counter (OTC) Medications
Abstract: According to Medicine, India's over-the-counter drug market is growing .The country's economy is expanding.The Indian pharmaceutical industry has experienced rapid growth in the last decade significant changes in the quality of business. The company actively promotes its products in the market; North Americans focus on finding cures for minor ailments compared to Europeans who rely on village pharmacists to treat minor ailments. Only the promotion and dissemination of public education …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 105–112 Read article
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Investigating the Role of Moisture in the Physical Properties of Harra (Terminalia chebula) Fruit
Abstract: Harra (Terminalia chebula) is known as the “king of medicines” in Ayurveda. Its fruits include astringent, purgative, antibacterial, antifungal, and laxative effects. The behavior of harra fruit is mainly dependent on the moisture present. It affects the harvest, post-harvest machinery, separation, packaging, and transportation of harra fruit. This study focused on T’s physical qualities of chebula fresh fruit at 20%–25% (wb) moisture content, such as 50 fruit mass, length, width, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 11–19 Read article
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The BambooBuddy: An AI-powered Chatbot for Enhancing Bamboo Yield in India
Abstract: Bamboo farming is essential for sustainable agriculture and environmental preservation. This project presents BambooBuddy, a chatbot developed to assist farmers and surveyors in managing bamboo-related inquiries. The system leverages a structured dataset stored in recommendations.csv to provide precise and relevant recommendations based on user queries. By utilizing the flask framework for web development and incorporating Cohere’s natural language processing capabilities, BambooBuddy facilitates seamless interaction and enhances user experience. The chatbot …
Published in Current Trends in Information Technology · Vol. 15, Issue 1, 2025 · pp. 12–18 Read article
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Contemporary Ethno-Religious Development Crises in Northern Nigeria with a Special Reference to Some States: Genesis, Implication, Impact and the Quest for Prospect
Abstract: A study has been conducted purely for the exploration of the remote and immediate factors that frequently lead to the outbreak of the studied subject matter in the region and period under review. In this study, a multitude number of published and unpublished sources have been put into use for appropriate historical reconstruction of some major obstacles associated with political, economic, social, tribal and religious aspects of the region and …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 32–40 Read article
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Opportunities & Challenges of Local Newspapers in Rural Communication
Abstract: Communication is essential to modern society, serving as the backbone of interactions and information sharing within communities. Among the various forms of media, local newspapers play a crucial role in shaping the development landscape of rural areas. They serve as vital sources of information that connect communities and facilitate development initiatives, bridging the gap between the government, non-governmental organizations, and rural residents. By providing important information about welfare schemes, agricultural …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 42–46 Read article
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Brain Tumor Detection Through CNN: Techniques, Dataset Insights, and Methodology
Abstract: Computer technologies are playing huge roles in some areas of the medical domain like surgery and therapy of different diseases. Researchers are doing studies and trying to experiment to detect different diseases like cancer, virus infections, and leprosy. There are many different medical imaging datasets that are publicly available for medical research purposes of diseases like cancer, virus infections, and leprosy, etc. where we can be able to access large …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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A Comparative Study of the Role of Local Newspapers in Rural Development in Three Selected Blocks in West Bengal
Abstract: This study aims to investigate and compare the role of local newspapers in facilitating rural development with a focus on three selected blocks in North 24 Parganas district in West Bengal, India. Local newspapers are a significant communication medium in rural areas, influencing community awareness, mobilization, and development initiatives. The study employed a mixed-methods approach, combining qualitative interviews, content analysis of newspapers, and surveys to comprehensively understand the impact challenges …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Transfer Learning in Deep Learning Models for Medical Imaging: Utilizing Pretrained Models to Improve Performance in Medical Image Analysis
Abstract: Transfer learning is now a trending technique in deep learning, especially in medical imaging. This technique solves landmark problems by utilizing the pre-trained models, including the limited availability of the annotated medical data and the time-consuming computational costs of training deep learning models from scratch. The generalizability of deep models could increase diagnostic precision for specific medical tasks, require fewer samples to train, and take less time to train due …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 1, 2025 · pp. 67–85 Read article
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Resource Reservation Approach: Application in Wireless Network
Abstract: This paper presents an enhanced resource reservation and call admission control strategy tailored for cellular networks. The proposed method uses user mobility trends to improve the efficiency of resource usage while avoiding significant network congestion. The call admission control mechanism is activated each time a new or handoff service request occurs, ensuring that resources are allocated efficiently to uphold a steady quality of service (QoS) for multimedia traffic. This mechanism …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 9–12 Read article
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Mechanical and Environmental Performance of Curaua Fiber Composites: A Sustainable Alternative to Wood and PVC
Abstract: This study examines the mechanical behavior of curaua fiber composites, comparing their performance to other materials like wood and PVC. Curaua fibers, sourced from the Brazilian Amazon, demonstrate superior mechanical properties, making them a promising alternative for sustainable composite materials. The composites were fabricated using various methods and subjected to tensile, flexural, and impact tests. Results show that curaua fibers exhibit an average tensile strength of 30.7 MPa, outperforming wood …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 467–477 Read article
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Street Light Automation and Fault Detection
Abstract: This paper addresses the concept, design, and implementation of an automated streetlighting system that uses Arduino technology for improving energy saving and detecting faults across the lamp. The system consists of several sensors: Light Dependent Resistors (LDR) as well as Infrared (IR) sensors, which are employed in the management to control the lighting of the streets and posts with surroundings and other conditions. Here, we use IR sensors for measuring …
Published in International Journal of Electronics Automation · Vol. 3, Issue 1, 2025 · pp. 12–20 Read article