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1907 articles for “Human epidermal growth factor receptors (HER-2)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Estimation of Alogliptin and Dapagliflozin in Synthetic Mixture by RP-HPLC Method
Abstract: The primary objective of the proposed research was to develop and validate analytical methods for the simultaneous quantification of Alogliptin and Dapagliflozin in a synthetic mixture. Alogliptin and Dapagliflozin are medications used for managing diabetes, with Alogliptin inhibiting the enzyme Dipeptidyl peptidase-4 and Dapagliflozin belonging to the class of sodium-glucose cotransporter 2 inhibitors. High-performance liquid chromatography method development was conducted using a C18 column (250 mmX4.6 mm, 5 μm particle …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 37–46 Read article
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The Economic Importance of Art and Craft: Men as Artisans at Ranchi Cluster in Jharkhand State
Abstract: There is an inseparable relationship between Art, culture and civilization in India. As man Gradually developed, art also kept on developing along with his civilization. Be it the civilization of any country. Its emergence has been the result of human imagination. Art has always had a significant historical significance, transcended cultural borders and acted as a monument to humanity's inventiveness and imagination. Artists have risen throughout history as guardians of …
Published in Recent Trends in Social Studies · Vol. 1, Issue 2, 2024 · pp. 47–56 Read article
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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Climate Change Impacts on Health: Addressing Temperature Variations With Homeopathic Solutions
Abstract: This study is focussed on the impacts of climate change on health, specifically focusing on temperature variations and proposing homeopathic solutions. Climate change, recognized as a critical issue of the 21st century, has wide-ranging effects on human health, including direct impacts such as heat-related illnesses and deaths, as well as indirect effects like increased prevalence of vector-borne diseases and food shortages. Vulnerable groups, including the elderly, are especially at risk. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Advancements and Challenges of Modern Breeding over Conventional Breeding
Abstract: Plant breeding dates back thousands of years, when people first deliberately bred plants based on visually pleasing characteristics. The domestication of wild plants aided this process, resulting in the evolution of numerous breeding strategies over time. Conventional breeding, which is distinguished by selective breeding based on superior performance, used procedures such as pure-line selections, mass selection, backcross breeding, recurrent selection, and hybridization. While effective, classical breeding procedures were time-consuming and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article
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Studies On The Length-Weight Relationship And Morphometric Characteristics of Rohu, Labeo Rohita (Hamilton) From Pond In Radhamohanpur, Jirania, Tripura, India
Abstract: The present study describes the length–weight (LWR) relationship and morphometric characters of 30 specimens of the rohu, Labeo rohita (Hamilton) collected from the pond situated in Radhamohanpur, Jirania, Tripura, India over a period of six months extending from (January 2020-June 2020). The fish were caught by traditional fishing gear. Total length (TL) reading has been taken from Vernier Calliper and Body weight (BW) measured with digital balance. The readings of …
Published in International Journal of Marine Life · Vol. 1, Issue 2, 2024 · pp. 27–34 Read article
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To Study Properties of Concrete by Using Manganese Ore Aggregate
Abstract: Aggregate is one of the major ingredients of the concrete and the maximum part of strength of the concrete is governed by the aggregate. And thus, partial or total replacement of it can change the physical as well as the chemical properties of the concrete. Nowadays researchers are quite interested in obtaining the more durable and more resisting concrete to the diverse climatic conditions. In this research, aggregate is proportionately …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 2, 2024 · pp. 38–45 Read article
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Integrating Network Pharmacology and Molecular Docking to Investigate Boerhavia diffusa for Pancreatic Cancer Treatment
Abstract: Objective: In this study, network pharmacology was applied to determine the therapeutic effects of the bioactive compounds of Boerhavia diffusa. Network pharmacology can unearth the underlying mechanisms between drugs and the disease targets and aids in the discovery of novel medications for complex conditions such as cancer. Methods: To predict the molecular mechanisms of action of Boerhavia diffusa in the treatment of was screened using the GeneCards database. The Venn …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 29–49 Read article
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Effects of the Embryonic Bisphenol an Exposure on The Postnatal Development, Learning and Memory of Rat Offspring: Fundamental Study
Abstract: We studied the morphologic changes in some organs and changes of learning and memory of the rat offspring after the embryonic bisphenol A exposure. Background: Bisphenol A, widely used as polycarbonate plastics material to manufacture food packaging, toys, glasses, computers, kitchen utensils and medical instruments, is one of the most common endocrine-disrupting chemicals. It is demonstrated that bisphenol A may be mingled with foodstuff and beverage from package and receptacle. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 58–63 Read article
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High-Definition Electroencephalography: A New Horizon in Neurological Pathology Research
Abstract: The advent of high-density electroencephalography (HD-EEG) has catalyzed a paradigm shift in the exploration of neurological pathologies. This editorial underscore its transformative potential in elucidating brain dynamics and refining diagnostic approaches for a spectrum of conditions, spanning from epilepsy and dementia to cognitive impairments in preterm infants. Our objective is to optimize the utility of HD-EEG by emphasizing the imperative for methodological homogenization and fostering collaborative endeavors. The remarkable spatial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 15–21 Read article
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Investigating the Relationship Between Environmental Concern and Waste Management in Tourism
Abstract: Tourism can bring both positive and negative effects in terms of the environment, which is the prevention of negative effects, including the necessity to preserve the environmental and even cultural, social resources of touristic areas. The purpose of this research is to investigate the relationship between environmental concerns and waste management in Damavand mountain tourism areas in 2017. This study was carried out as a survey and is of the …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 47–53 Read article
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Metabolic Reprogramming in Carcinogenesis: An Overview
Abstract: Metabolic reprogramming is a crucial mechanism via which cells modify their metabolic pathways to adjust to changes in the environment and maintain growth, survival, and function. This phenomenon is of utmost importance in a wide range of physiological and pathological situations, specifically in cancer, immunological responses, and stem cell biology. In cancer, metabolic reprogramming facilitates fast cell growth and survival, as demonstrated by the Warburg effect, where cancer cells prioritize …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article
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Platelets A Tiny Cell Fragments
Abstract: Platelets are disc-shaped, anucleate cells that are approximately 2-3 μm in diameter. Their primary function is to control hemostasis, or blood clotting, but they also play important roles in angiogenesis (the formation of new blood vessels) and innate immunity (the body's first line of defence against infection). With a diameter of just 2-3 microns, platelets are tiny, disc-shaped cells that lack a nucleus. While their main responsibility is to ensure …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 22–28 Read article
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A Study on the Knowledge of Arterial Blood Gas (ABG) Analysis Among Staff Nurses in a Rural Hospital Setting
Abstract: To evaluate the comprehension of Arterial Blood Gas (ABG) analysis among staff nurses in a designated Rural Hospital, this study aimed to assess their knowledge level and correlate it with specific demographic variables. Utilizing a descriptive approach, the study encompassed all staff nurses within the Rural Hospital, with a sample of 50 individuals meeting the inclusion criteria: completion of either a Diploma in Nursing and Midwifery (GNM) or a Degree …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 1–21 Read article
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An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Rauwolfia Serpentina: A Comprehensive Phytochemical Study of Its Bioactive Metabolites
Abstract: Rauwolfia Serpentina is an important medicinal plant used in Ayurveda, Unani, and folk medicine system of medicine. This plant grew as a bush in company of other plants as an evergreen structure. It is commonly known as ‘Sarpaghanda’. in Ayurvedic and Unani medicine system. It is safe and effective for the treatment of snakebites and various types of disease like malaria, breast cancer, prostate cancer, high blood pressure, insomnia, epilepsy, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 25–50 Read article
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Analytical and Statistical Analysis of Reinforced Concrete Frame Structure Subjected to Blast Loading
Abstract: Blast loading represents one of the most hazardous and destructive forces that structures may encounter throughout their life span. Understanding and mitigating the effects of such loading is crucial for ensuring the safety and resilience of buildings. This study focuses on analyzing the behavior of reinforced concrete (RC) frame structures when subjected to blast loading, with the aim of informing more robust and resilient building designs. The research specifically examines …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 84–91 Read article
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Mapping the Literature on Digital Payment: A Comprehensive Review and Bibliometric Analysis
Abstract: This study essentially performs a comprehensive and in-depth analysis of the current research on digital payment systems. It examines and evaluates 346 journal papers from reliable sources like Scopus and Web of Science that were published between 2015 and 2023. The study intends to give readers a thorough grasp of the state of the art in the field of digital payments research, pinpoint new directions, and emphasize important issues. Among …
Published in International Journal of Optical Innovations & Research · Vol. 2, Issue 1, 2024 · pp. 41–59 Read article
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article