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1969 articles for “quantum mechanics/molecular mechanics (QM/MM)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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Comparative Experimental Investigation of Infill Pattern and Infill Density on Fused Deposition Modeling (FDM) Process Characteristics of Polylactic Acid (PLA)
Abstract: Additive manufacturing is the potential and emerging technology widely being used to produce quality products with complicated profiles and customized features. Fused Deposition Modelling (FDM) process, a type of additive manufacturing technology using filament made of thermoplastic which is melted and subsequently extruded through nozzle. The main input process parameters of FDM are wall thickness, infill density, layer height, bed temperature, layer thickness, infill pattern, nozzle temperature etc. In this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 335–345 Read article
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Advanced Techniques in Filler Layering for the Malar Region: Implications for Cellular Integrity and Long-Term Outcomes
Abstract: Objective: This review investigates advanced filler layering techniques for the malar region, focusing on cellular integration, collagen remodeling, hydration dynamics via aquaporin channels, genetic responses, and filler performance over time. Emphasis is placed on high-density HA fillers (Lyft, Voluma, Volift, and Volux), examining cellular-level mechanisms, genetic interactions, and the role of key pathways (TGF-β, ERK/MAPK, AQP3) in long-term outcomes. Methods: A systematic review was conducted, focusing on genetic, cellular, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 10–19 Read article
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Affect of Finite Element Modelling on Static Behavior of Underwater Shell
Abstract: The objective of the present study is to compare and contrast different numerical models based on their mesh quality and material properties in predicting the response of an underwater shell under an external pressure of 1 MPa. Two different mesh qualities with the same element size are developed for solid geometries without and with slicing the solids at geometric discontinuities to enhance the element quality. From the static response of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 154–163 Read article
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An Overview of Composite Materials: Historical Development, Classification, and Advancements in Natural Fiber-Reinforced Polymer Composites
Abstract: Composite materials have brought about a paradigm shift in numerous industries by integrating distinct components to improve material performance. Consisting of a matrix and reinforcement, composites synergistically combine the unique properties of each constituent to deliver superior strength, enhanced durability, and remarkable flexibility. These attributes have made composite materials indispensable in diverse fields such as automotive, aerospace, construction, and marine engineering. This article provides a comprehensive exploration of the historical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 158–175 Read article
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Study on Chemical Insights into Alzheimer's Disease: Amyloid Beta and Tau Protein Interactions
Abstract: Background: Alzheimers disease (AD) is the most prevalent form of dementia, affecting millions of individuals worldwide and posing significant challenges to healthcare systems. The disease is characterized by a gradual decline in cognitive functions, particularly memory, reasoning, and the ability to perform daily activities. Aim & objective: To study chemical insights in alzheimers disease, especially amyloid beta and tau protein interactions Results & discussion: The results of this review highlight …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 37–46 Read article
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Material Characterization Analysis of Fiber Reinforced Composites
Abstract: The study investigates the physical characteristics of PAN carbon fabric/epoxy composite which is a material commonly utilized in aerospace, defense, and automotive sectors. The material has exceptional mechanical properties like high specific strength and hardness. The materials utilized in this experiment are T-300 PAN carbon fabric, LY556 Epoxy resin, and HY5200 hardener to create pre-preg materials. Then the laminate was pre- pregged in a die mold of identical shape matched, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 230–243 Read article
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Smart Firefighting Robot using Arduino Uno
Abstract: A fire is dangerous and can have many repercussions. Numerous accidents can be avoided by promptly identifying and putting out a fire. Human resources have been our mainstay thus far. The person's life is often in jeopardy as a result. Consequently, fire safety becomes essential to save lives. The fire extinguishing robot proposed and designed in this work locates the fire and utilizes sprinklers to extinguish it when the pump …
Published in International Journal of Electronics Automation · Vol. 3, Issue 1, 2025 · pp. 21–27 Read article
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Advancements In Al6061 Metal Matrix Composites: The Role of SiC, Al₂O₃, and Graphite Reinforcements in Enhancing Properties and Applications
Abstract: Al6061-based metal matrix composites (MMCs) reinforced with silicon carbide (SiC), graphite (Gr), and aluminum oxide (Al₂O₃) exhibit a unique combination of mechanical, thermal, and tribological properties, making them highly suitable for advanced engineering applications. SiC enhances hardness, wear resistance, and load-bearing capacity, while Al₂O₃ improves thermal stability and mechanical strength. Graphite provides self-lubricating properties, reduces friction, and lowers the composite's density, improving fatigue resistance. The synergy of combining these reinforcements …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 90–98 Read article
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Long Non-Coding RNAs: Key Regulators of Gene Expression in Development and Disease
Abstract: Long non-coding RNAs (lncRNAs) are RNA molecules that do not make proteins but are essential for controlling how genes are turned on or off in the body. These molecules help with various biological functions, such as guiding cell growth, shaping development, and influencing the progression of diseases. Recent advancements in genomics and transcriptomics have revealed the vast and complex roles of lncRNAs, with an increasing recognition of their involvement in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article
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Development of an Easy Car Moving Kit Using a Hydraulic Cylinder
Abstract: A wheel dolly that can be used as an automotive jack and can support heavy loads in the air for lengthy periods without the need for hydraulic systems is revealed. In a further aspect, when the vehicle’s engine fails, and is not able to move on its own, to move the vehicle with the help of human power or another vehicle is taken. For moving a car, portable dolly kits …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 32–40 Read article
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Fabrication of Natural Fibre Reinforced Polymer Composite by Hand Lay-Up Process
Abstract: The recent development in technologies has increased the usage of non-renewable resources during pro- duction due to remarkable properties. However, it has been a threat and unable to be replenished once used. In addition to this, natural fibre strengthens in a more significant way and it’s widely applicable in polymer composites materials. Furthermore, the use of plant fibres in polymer composites is due to its low cost and significant properties. …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 13–19 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Computers: Evolution, Breakthroughs, and Future Innovations
Abstract: The computer, a cornerstone of modern technology, has evolved through significant inventions and innovations that have transformed societies and industries worldwide. From the early mechanical calculating machines, such as Charles Babbage’s Analytical Engine, to the advent of electronic computers like the ENIAC, the journey of computing is marked by breakthroughs that have enabled rapid advancements in data processing, communication, and automation. The introduction of integrated circuits, microprocessors, and the development …
Published in Trends in Opto-electro & Optical Communication · Vol. 15, Issue 2, 2025 · pp. 11–23 Read article
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A Review on Kaempferol Eye Drops for the Glaucoma Treatment
Abstract: One of the main causes of permanent blindness, glaucoma is defined by gradual damage to the optic nerve, mostly brought on by oxidative stress, neuroinflammation, and high intraocular pressure (IOP). The investigation of herbal alternatives is necessary since current synthetic therapies, such as beta-blockers and prostaglandin analogs, frequently result in ocular discomfort, systemic toxicity, and poor patient compliance. Clitoria ternatea contains kaempferol, a bioactive flavonoid that has shown anti-inflammatory, antioxidant, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 110–121 Read article
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Performance Evaluation of Hybrid Polymer Composite Materials for Electromagnetic Interference Shielding in Flexible and Wearable Electronic Devices
Abstract: Wearable electronic devices require novel hybrid polymer composites that offer flexible, lightweight and highly effective EMI shielding characteristics. The development and characterization of flexible polymer composites combining hard magnetic nanoparticles and electrically conductive fillers are explored. The suitability of thermoplastic polyurethane (TPU), polydimethylsiloxane (PDMS) and epoxy resins for use as EMI shielding composite matrices was evaluated in terms of their flexibility, stability and biocompatibility. Hybrid filler systems were developed to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 630–648 Read article
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Role of Fatigue and Creep in Structural Damage: A Comprehensive Review
Abstract: Fatigue and creep are two critical degradation mechanisms that significantly influence the structural integrity and longevity of engineering materials. These phenomena arise due to different loading and environmental conditions but often coexist in various industrial applications, leading to severe material degradation over time. Fatigue primarily results from cyclic loading, where repeated stress variations induce microstructural damage and crack initiation, ultimately causing catastrophic failure. Conversely, creep occurs under sustained stress at …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 1, 2025 · pp. 22–26 Read article
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Process Parameters Optimization of Fiber Laser Cladded SS316 Surface Using RSM Analysis
Abstract: This paper presents the laser cladding experiments on the surface of SS316 to study the variations in process parameters, such as scanning speed (100-250 mm/min), laser power (50-250 W), and % volume of B4C (5- 25%) + SS316 powder on the mechanical, metallurgical and tribological performance of the modified surface. A central composite design (CCD) was used to develop the response surface methodology (RSM) to design the experiments and for …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 186–201 Read article
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Effect of Hybridization on Tensile and Flexural Strengths of Carbon, Glass and Steel Fiber Composites: A Comparative Study
Abstract: Fiber reinforced polymer composites are widely recognized for their high strength-to-weight ratio, excellent corrosion resistance, and design flexibility making them ideal for various engineering applications. Despite their numerous advantages, traditional composites possess significant limitations such as restricted mechanical performance under diverse loading conditions. To address this, hybrid fiber polymer composites are developed while enhancing material performance. In the present study, synthetic (carbon, glass) and metallic (steel) fiber reinforced composite materials …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 621–635 Read article
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Bio-inspired Thermo-responsive and Self-Healing Polymer–PCM Hybrids for Next-Generation Smart Textile Applications
Abstract: The integration of phase change materials (PCMs) into flexible polymers represents a promising strategy for developing smart textiles with advanced thermal regulation and mechanical adaptability. However, the challenges of PCM leakage, poor mechanical strength, and durability under cyclic stress have limited their practical applications. In this study, we present a novel self-healing and elastic composite based on thermoplastic polyurethane (TPU) incorporating 30 wt% microencapsulated PCM (mPCM) and dynamic disulfide bonds …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 228–238 Read article