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1223 articles for “insights”
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Computational Investigation of Withania somnifera Compounds Targeting S. pombe SMN YG-Dimer in Spinal Muscular Atrophy: Insights from Molecular Docking Analysis
Abstract: Objectives: The primary objective of this study is to determine the potential of phytochemical constituents of Withania somnifera in treating spinal muscular atrophy, an autosomal recessive genetic neurodegenerative disorder, through computational techniques. To investigate the binding affinity of phytocompound to the target protein S. pombe SMN YG-Dimer through molecular docking. Besides, evaluating the pharmacological attributes of phytochemical constituents to assess their ability as an ideal prospect for developing therapeutic medication. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 39–52 Read article
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The Transformative Journey of Pregnancy: Insights into Maternal Adaptations
Abstract: During pregnancy, a woman’s body changes in many ways because of hormones. These changes can sometimes be uncomfortable, but most of the time they are normal and enable her to nourish and protect the fetus, prepare her body for labor, and develop her breasts to produce milk. During pregnancy, changes in hormone levels drive a wide range of physical transformations in a woman’s body, all of which play an essential …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 84–92 Read article
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The Role of Bioinformatics in Nursing: Transforming Healthcare through Data-Driven Insights
Abstract: Bioinformatics, an interdisciplinary field combining biology, computer science, and information technology, is increasingly shaping the nursing profession. It offers powerful tools for improving patient care, advancing clinical research, and enabling personalized healthcare through data-driven decision-making. This article examines the integration of bioinformatics into nursing practice, tracing its historical roots from the Human Genome Project to its current applications in genomic medicine, precision healthcare, and population health. Nurses now play a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 18–21 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Advanced Control Techniques: Super-twisting Controller Applications and Insights
Abstract: Sliding mode control (SMC) provides robust control for uncertain systems. This study focuses on the Super-Twisting Controller (STC), a powerful SMC technique known for its finite-time convergence and robustness. Its importance is to provide chatter-free control and robustness against uncertainty, and make it suitable for systems with nonlinear dynamics and disturbances. The advantages of STC are faster speed, more accurate control actions, and enhanced system stability, though may require careful …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 2, 2024 · pp. 1–7 Read article
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Genetic Variability and Statistical Methods: Key Insights for Computational Genetics Research
Abstract: Genetic variability, defined as the differences in DNA sequences among individuals, serves as the foundation of evolutionary biology and plays a pivotal role in species’ adaptability, resilience, and overall survival. Advances in genomic technologies, particularly high-throughput sequencing, have enabled unprecedented exploration of genetic diversity, fostering the growth of computational genetics. This interdisciplinary field combines statistical methods and computational tools to analyze genetic data, identify patterns, and link phenotypes to genotypes. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 19–23 Read article
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Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy
Abstract: This review provides an in-depth exploration of the evolution of ointment formulations, particularly considering the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges, such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift toward more advanced, innovative formulations that aim to address …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 14–23 Read article
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Exploring The Performance Dynamics of Basalt Fibre Reinforced Polymers: Mechanical and Viscoelastic Insights
Abstract: Basalt fibre reinforced polymer (BFRP) composites are gaining significant attention as sustainable alternatives to traditional reinforcement materials due to their superior mechanical performance, thermal stability, and eco-friendliness. This study examines the tensile, flexural, impact, and viscoelastic properties of BFRP composites fabricated via vacuum-assisted resin transfer molding (VARTM) using varying fibre volume fractions (20%, 30%, and 40%) and fibre orientations (unidirectional and bidirectional). The results reveal that composites with 40% fibre …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 12–22 Read article
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Holistic Ayurvedic Approach to Managing Vicharchika (Eczema): Insights from a Case Study
Abstract: Background: Eczema is a common skin condition characterized by inflammatory reactions, manifesting as erythema, scaling, and itching. Nipple eczema is a localized dermatitis involving the nipple and areolar region, characterized by erythema and scaling. It may be itchy and painful and occasionally affect non-atopic breastfeeding women. Eczema has quite a resemblance with Vicharchika in Ayurveda. Vicharchika is characterized by skin manifestations having the symptoms Kandu (itching sensation), Pidika (papule), Shyava …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 · pp. 1–9 Read article
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Brain Tumor Detection Through CNN: Techniques, Dataset Insights, and Methodology
Abstract: Computer technologies are playing huge roles in some areas of the medical domain like surgery and therapy of different diseases. Researchers are doing studies and trying to experiment to detect different diseases like cancer, virus infections, and leprosy. There are many different medical imaging datasets that are publicly available for medical research purposes of diseases like cancer, virus infections, and leprosy, etc. where we can be able to access large …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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Data Mining for E-Commerce and Social Media: Insights and Future Research Directions
Abstract: The fast expansion of e-commerce and social media has heralded a new era of data-rich settings, with enormous quantities of user interactions, preferences, and transactions generated on a daily basis. Data mining has developed as a critical strategy for leveraging big datasets, allowing businesses to gain concrete knowledge and drive decision-making. Data mining in e-commerce improves operational efficiency and user pleasure by allowing for personalized recommendations, consumer segmentation, fraud detection, …
Published in E-Commerce for Future & Trends · Vol. 12, Issue 1, 2025 · pp. 14–23 Read article
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Enhancing Performance of Hybrid Natural Fiber Reinforced Polymer: Insights into Processing, Characterization and Machining
Abstract: Natural fibre reinforced polymer composites (N-FRP) have gained popularity in recent years as an alternative to regular polymer composites, owing to growing environmental concerns. Natural fibers are becoming increasingly popular due to their outstanding properties such as flexibility, strength, compatibility with living creatures, and impact resistance. A notable application of natural fibers is in the medical industry, with the goal of producing cost-effective, sustainable, and long-lasting products. Combining different fibers …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 139–153 Read article
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An Insight Review of Autonomous Vehicle Architecture, Sensors, and Challenges
Abstract: Autonomous vehicles (AVs) are revolutionizing transportation by integrating advanced sensors, artificial intelligence, and communication networks to enhance safety and efficiency. This review explores the architecture of AVs, focusing on perception, localization, path planning, and control. A detailed analysis of AV sensors, including LiDAR (light detection and ranging), radar, cameras, and inertial navigation systems, highlights their roles, advantages, and limitations. Additionally, the paper examines in-vehicle and inter-vehicle communication networks, such as …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 1, 2025 · pp. 29–42 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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CNN-BILSTM Architectures for Handwritten Signature Verification: Insights and Innovations
Abstract: Verifying handwritten signatures is essential for identity authentication to guard against fraud and guarantee security across a range of platforms. The approaches and developments in handwritten signature verification are examined in this review, with an emphasis on both offline and online techniques. While online methods use dynamic information like stroke order and speed, collected by specialized devices, offline verification uses scanned photographs of signatures. Even if technology is moving toward …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 2, 2025 · pp. 43–50 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Infection Control awareness among Nursing students: Descriptive Insights from Ongoing Clinical Orientations in Odisha
Abstract: Background: Effective infection control practices are critical in preventing healthcare-associated infections (HAIs). Aim: This study aimed to assess the awareness regarding effective infection control measures among student nurses undertaking their initial clinical orientations at Hospitals. Method: The study accepted 64 respondents from II-year BSc Nursing, sampled in clusters from selected Hospitals, Odisha. Results: The students yielded a mean awareness score of 0.69, categorized as Good. A comparison revealed that female …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article
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Cervical Leiomyomas: Age associated insights from 3 Year prospective study from Tertiary Care Hospital
Abstract: Cervical leiomyomas are rare benign smooth muscle tumours of cervix, often presenting diagnostic challenges due to their uncommon occurrence and overlapping features with other cervical pathologies. This is a 3-year prospective study involving a total of 460 female subjects who were diagnosed with various gynecologic complications, with a particular focus on cervical leiomyomas. The study aims to provide a comprehensive age-wise distribution of cervical leiomyomas, emphasizing the incidence and prevalence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Parasites and Public Health: Global Challenges and Emerging Insights
Abstract: Parasitic illnesses are still a big problem for health around the world, especially in developing nations where sanitation and access to healthcare are restricted. Protozoa, helminths, and ectoparasites are all types of parasites that can damage many organ systems and cause both short-term and long-term health problems. This article looks at how parasites affect human health in different ways, focussing on common infections including malaria, schistosomiasis, and toxoplasmosis. Parasitic infections …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 8–15 Read article
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The Impact of Geographical Indications on Sustainable Rural Development: Comprehensive Economic and Cultural Insights from Wayanad, Kerala
Abstract: Geographical Indications (GIs) play a vital role in fostering sustainable rural development by linking unique local products to their geographic origins. This study explores the impact of GIs on economic growth, cultural preservation, and environmental sustainability in Wayanad, Kerala. Drawing from extensive secondary data and detailed case studies including Wayanad Coffee, Jeerakasala Rice, and traditional handicrafts, the research highlights how GI certification enhances market value, improves income levels, and preserves …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 2, 2025 · pp. 18–29 Read article