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320 articles for “cause”
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Rotenone effects on the human body with reference to neurological disorder
Abstract: It has been claimed that the well–known neurotoxic pesticide rotenone, which is known to block the mitochondrial complex I, is strongly linked to the pathophysiology and etiology of Parkinson's disease (PD) in humans. There have been numerous analyses in the past and are still being conducted to establish a relationship between the two in order to completely comprehend the level of harm brought on by rotenone. Numerous laboratory studies shown …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 21–27 Read article
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Strengthening Neurological and Familial Interventions: Adult Coping Following Pediatric Brain Injury and Comorbidity
Abstract: Background: Pediatric traumatic brain injury (PTBI) contributes to long-term physical, cognitive, and emotional difficulties and is a major cause of mortality and disability in children. An estimated 200,000 fatalities in India each year are attributed to traumatic brain injuries, with PTBI accounting for a significant share of these cases. Accidents, abuse, and sports injuries are just a few of the causes of post-traumatic brain injury (PTBI), which can result in …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 7–15 Read article
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Assessing the Impact of a Structured Educational Initiative on Awareness of Vaginitis and Its Prevention Among Adolescent Girls in Selected Higher Secondary Schools in Bengaluru
Abstract: Background and Objectives: Vaginal inflammation, referred to as vaginitis, may culminate in discharge, itching, and pain. Usually, the root cause is an infection or an altered in the balance of the microbes in the vagina. In females between the ages of two and six, poor perineal hygiene—such as wiping after bowel movements from back to front or not washing hands afterward—is an important contributory factor. Another typical sign is frequent …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 10–21 Read article
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Evaluation of Small Vessel Disease by Advanced Brain Imaging
Abstract: Studying and comprehending brain small vessel disease requires extensive imaging. Recent applications of cutting-edge brain imaging techniques have led to the discovery of several significant results. Diffusion-weighted MRI studies have demonstrated the diagnostic accuracy of using clinical features alone or in combination with CT scan results to identify small vessel disease as the underlying cause is suboptimal in patients with acute lacunar syndromes. Acute infarcts caused by small vessel disease …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 15–19 Read article
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Multi-Target Molecular Docking of Anantmul (Hemidesmus indicus) Compounds for Tay-Sachs Disease Treatment
Abstract: This research aimed to study the effects of the plant Anantmul (Hemidesmus indicus) in the treatment of Tay-Sachs disease using molecular docking studies. Tay-Sachs disease is a neurodegenerative autosomal recessive disorder caused due to accumulation of the molecule GM2 ganglioside which is caused due to lack of enzyme Beta Hexosaminidase which breaks down GM2 Ganglioside. Anantmul (Hemidesmus indicus) is a an ayurvedic plant used in the Indian subcontinent that has …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 61–69 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Market Architecture, an Effect of Roadside Trading in Port Harcourt Metropolis. A Case Study of Rumu-Woji Market, Rivers State, Nigeria
Abstract: The challenges of road side trading along major market roads in Port Harcourt Metropolis has brought about certain menace to the city. The efforts put in place by the Rivers State government to eradicate the act of roadside trading along market roads have been proven abortive. Various means employed by the government to stop the act of roadside trading have not been successful such as, relocation of traders, barricading market …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 36–46 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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The Calcium Paradox – Calcium Dietary Intake and Supplementation in the Context of Calcium Oxalate Renal Calculus
Abstract: Renal Calculi, also known commonly as kidney stone is one of the most common manifestations of kidney function dysregulation causing discomfort and alterations to an individual’s life. Although kidney stones come in a variety of forms, calcium oxalate stones are the most prevalent kind. These Calcium Oxalate renal stones often arise from various issues like metabolic imbalances, dehydration and dietary imbalances. About 70–80% of kidney stones are calcium oxalate stones, …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 17–25 Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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The War's Economic Effects in the Twenty-First Century, Both Locally and Internationally
Abstract: The essay looks at how wars in the twenty-first century have affected the economy both theoretically and practically. The idea of the "military economy" is emphasized. Analysis is done on the dynamics of military spending. The causes and forms of conflicts that have taken place in the past and are happening now are explained. Researching the economic effects of Russia's war in Ukraine is emphasized. The pre-war evaluation of nations' …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 14–21 Read article
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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A Study to Evaluate Nurse Led Intervention Regarding Home Care Management Among Tuberculosis Patients Attending Chest and TB OPD at PGIMS Rohtak
Abstract: Introduction: Tuberculosis is an infectious bacterial pathogen caused by the bacillus called Mycobacteriumtuberculosis, an acid-fast rode shaped bacillus 0.8–5 μm in length and 0.2–0.6 μm in thickness. Tuberculosis (TB) primarily impacts the lungs (pulmonary TB), but it can also affect other parts of the body (extra-pulmonary TB). It spreads through the air and causes damage to the lungs and various other organs. TB is a significant public health issue in …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 31–36 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Ramifications of Industrial Pollution: Problems and Ways to Fix Them
Abstract: Pollution from industry is still one of the largest environmental challenges of the 21st century. It hurts the air, water, and land all around the world. This page discusses about the primary kinds of pollutants that arise from factories, such as heavy metals, particles, and toxic chemicals. It studies at how industrial emissions affect people and the environment, such as by causing respiratory problems, harming ecosystems, and changing the climate. …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 2, 2025 · pp. 1–5 Read article
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From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article