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93 articles for “bio-stimulant”
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Self-Healing Polymer Nanocomposites: A Comprehensive Review of Design Strategies, Mechanisms, and Emerging Applications
Abstract: Self-healing polymer nanocomposites (SHPNs) are a new class of materials that can autonomously repair themselves to prolong their lifetime and improve their application performance. Herein, we provide a comprehensive overview of the design strategies, healing mechanisms, and emerging applications of SHPNs. Incorporating nanofillers (nanoparticles, nanofibers, and/or nanotubes) into polymer matrices leads to requisite functionalization that significantly enhances mechanical properties and is essential in self-healable products including improved cross-linking, high dispersion, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 281–293 Read article
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Integrating Livestock for Enhancing Sustainability of Soil, Water and Agroecosystem: Implications from a One Health Perspective
Abstract: Livestock systems play a pivotal role in sustaining environmental health, enhancing ecosystem services, and supporting agricultural productivity. Well-managed integration of livestock into agroecosystems contributes to soil fertility through organic matter deposition, microbial stimulation, and nutrient cycling, while improving soil structure and long-term productivity. Grazing and pasture management regulate water infiltration, retention, and hydrological balance, mitigating soil erosion and enhancing water-use efficiency. Livestock also promote biodiversity by maintaining habitat heterogeneity, facilitating …
Published in International Journal of Sustainability · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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Aerodynamic Analysis of Foliage Stimulated Airfoil Design for Enhanced Strength with Carbon Fibre-reinforced Polymer
Abstract: Ever since the beginning of aviation, there has been an unwavering desire to improve airfoil design in order to improve aircraft performance. This insatiable desire for improvement has driven innumerable aerodynamicists to create a diverse range of revolutionary airfoils. This research investigates a revolutionary method to airfoil design, inspired by the complicated structures and aerodynamic qualities of natural leaves. Using biomimicry, the project seeks to increase the performance and efficiency …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 560–616 Read article
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Polymer Chemistry-Driven Approaches for Improved Therapeutic Delivery
Abstract: Polymer chemistry has revolutionized pharmaceutical technology by enabling the development of advanced drug delivery systems with improved precision, stability, and therapeutic outcomes. This review explores the role of polymer design, synthesis, and functionalization in the development of responsive and targeted drug carriers. Emphasis is placed on various types of polymers—biodegradable, synthetic, natural, and stimuli-responsive—and their suitability for drug delivery platforms such as nanoparticles, micelles, hydrogels, dendrimers, and implants. The physicochemical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Arabidopsis thaliana. (L.) Heynh Multifunctional Sensor Proteins and Signaling Networks Plant Photoreceptors
Abstract: Light is a crucial environmental cue for the growth and development of plants as well as the production of photosynthetic energy. In order to recognize and process information from incoming light, plants employ sophisticated mechanisms. With the model plant Arabidopsis thaliana, five different types of photoreceptors have been found. (L.) Heynh Photoreceptors play a specialized and/or recurring role in fine-tuning many aspects of the plant's life cycle. Unlike mobile animals, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 08–24 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Polymer Chemistry in Shoulder Orthotics
Abstract: The design of effective shoulder orthotic devices has increasingly made use of polymeric materials because of their versatility, durability, and biocompatibility. This review illustrates polymer chemistry role in constructing an orthotic device for shoulder subluxation, which is a commonly occurring post stroke or injury condition. Proprietary design elements such as polypropylene are rigid yet moldable which help in anatomical formulating for joint stabilization. On the other hand, rubber elastomers, medicinal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 21–28 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Self-Healing Polymer Composites for Pharmaceutical Packaging Applications
Abstract: Pharmaceutical packaging plays a crucial role in ensuring the safety, stability, and effectiveness of pharmaceutical products. Conventional polymer-based packaging materials are prone to mechanical damage, microcracks, and environmental degradation, which can compromise drug integrity. Self-healing polymer composites (SHPCs) offer a promising solution by enabling autonomous or stimuli-responsive repair mechanisms that restore packaging integrity, enhance durability, and extend product shelf life. These materials function through intrinsic mechanisms, such as dynamic covalent …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 648–658 Read article
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Role of Functional Regenerative Trilaminar Scaffold Dressing in Wound Bed Preparation
Abstract: Advancements in wound healing have incorporated tissue regeneration therapy as a crucial tool for managing both acute and chronic wounds. Bio constructs designed to facilitate wound regeneration utilize natural, artificial, or hybrid materials, collectively referred to as regeneration scaffolds. The components of regeneration scaffolds play a crucial role in enhancing the skin's natural self-renewal abilities and accelerating the healing process. These scaffolds are designed to provide essential growth factors and …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 70–75 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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A Review of Herbal Photoprotective Agents: From Traditional Knowledge to Modern Sunscreen Formulations
Abstract: Continuous exposure of skin to UV rays leads to tanning, premature aging, sunburn, pigmentation, and skin cancer. Sunscreens are widely used to protect the skin from these harmful stimuli. However, sunscreen components may interfere with other health concerns like irritation, itching, allergic reactions, and distinct environmental damage. This major concern initiated the introduction of herbal photoprotective agents, which are eco-friendly, safer for use, and rich in antioxidants (preventing free radicals). …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 8–13 Read article
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Phyto Biotics in Aquaculture
Abstract: This paper aims to assess the existing knowledge on the use and effects of phytobiotics in fish farming, as well as their potential for broader application in aquaculture. With the rising demand for fish, there has been a noticeable decline in fish production in recent years, which could be a driving factor behind the increasing interest in using phytobiotics in this field. The main factor contributing to the decrease in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 18–22 Read article