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109 articles for “acetic acid”
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Quantitative Determination of Isomeric Components of essential oils by RP-HPLC-PDA in multi-herbal tablets
Abstract: Essential oils are lipophilic and highly volatile secondary plant metabolites, principally mono- and sesquiterpenes. The widespread usage and applications in biopharmaceutics and cosmoceutics of these components drives their quality assessments criteria to be established. Gas chromatography is one of the predominantly used technique for analyzing volatile oils. Although Gas Chromatography employs estimation designs operated at elevated temperatures leading for plausible structural alterations of thermo labile compounds. Hence, a novel gradient …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 19–28 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Evaluation of Biomedical Importance of Papaya Pulp
Abstract: The present study describes the preparation of petroleum ether, ethyl acetate, and methanol extract from Carica papaya; further the extracts revealed dose dependent anti-oxidant potential. Among the extracts, ethyl acetate extract showed more percentage of scavenging than other two extracts. The screening of antimicrobial activity for three extracts revealed antimicrobial potency towards 12 test organisms. Among these extracts, petroleum ether shows more activity against 12 microbes compared with other two …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 3, 2017 · pp. 14–19 Read article
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Smoking and Body Weight: Is There Any Relation?
Abstract: Tobacco is a tall, green leafy plant, originally grown in South and Central America, but now cultivated throughout the world. The link between smoking and body weight is evident as early as adolescence. Nicotine acts on nicotinic cholinergic receptors in the brain and autonomic ganglia. The binding of nicotine to the nicotinic receptors opens ion channels, allowing entry of sodium and calcium, thereby; augment the release of various neurotransmitters. This …
Published in Research and Reviews: A Journal of Health Professions · Vol. 3, Issue 3, 2013 · pp. 33–36 Read article
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Free radical scavenging effect of various extracts of Root of Shirisha (Albizia lebbeck (L.)Benth.) by DPPH method
Abstract: The study of antioxidants and free radicals in biology is producing medical revolution that promises a new age disease and health management. The present study was performed to evaluate the in vitro antioxidant effect of the methanol, ethyl acetate, hydro alcohol and water extracts of Albizia lebbeck (L.) Benth. by using DPPH method. The ethyl acetate extract exhibited significant inhibition in DPPH free radical formation with IC50 values of 70.5206. …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 10, Issue 3, 2019 · pp. 12–16 Read article
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Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review
Abstract: A complex disorder of hunger control and energy metabolism driven by certain biological variables is obesity. This study aims to evaluate the applications of Garcinia cambogia products for appetite suppression and fat burning. This little fruit, which looks a lot like a pumpkin, is marketed and used most frequently these days as a weight-loss supplement. Research has demonstrated that the fruit rind's main organic acid component, (−)-hydroxycitric acid (HCA), and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 08–14 Read article
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Bioanalytical Method Development and Validation for the Estimation of Levothyroxine in Human K₃EDTA Plasma by Using UPLC-MS/MS
Abstract: A rapid, sensitive, and highly selective UPLC-MS/MS method was developed and validated for the quantitative estimation of Levothyroxine in human plasma using Levothyroxine-D₃ as the internal standard (IS). Chromatographic separation was achieved on a Gemini NX-C18 column (50 × 3.0 mm, 3 µm) with a mobile phase consisting of acetonitrile and water (70:30, v/v) containing 0.015% formic acid at a flow rate of 0.5 mL/min. The total run time was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 32–46 Read article
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Starter Culture Development for Spontaneously Fermented Buttermilk
Abstract: Fourteen fermented milks were made from ultra-high temperature (UHT) treated milk using mixtures of three strains of lactic acid bacteria (LAB) and two yeast strains isolated from spontaneously fermented buttermilk (SFB). The isolates used for this experiment were Lactococcus (Lc.) lactis ssp lactis strain NGLC1, Lc. lactis ssp lactis strain NGLC2, Lactobacillus plantarum strain NGLB1, Saccharomyces cerevisiae strain NGY1 and Kluyveromyces marxianus strain NGY2. Inoculated milk was fermented for 48 …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 1, 2016 · pp. 11–25 Read article
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“High Melatonin Milk”- Milk with Intrinsic Health Benefit
Abstract: Melatonin C13H16N2O2 (molecular weight: 232) or N-acetyl-5-methoxytryptamine, is chemically an indoleamine and derived from the essential amino acid tryptophan. It is a hormone and due to secretion from pineal gland, it is also called as active pineal factor. Its IUPAC name is N-[2-(5-methoxy-1H-indol-3-yl)ethyl] acetamide. The indole ring acts as the chromophore showing maximum absorbance at 223 nm, and the functional groups contribute to its fluorescence property. Lerner et al. 1959 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 13–16 Read article
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Gas Sensors Fabricated using Carbon Powder Derived from Dried Banana Peels Waste to detect Methanol, Ethanol, Acetone Vapors and Carbon Dioxide Gas
Abstract: Low cost and environmentally friendly activated carbon powder was synthesized using waste banana peels. Phosphoric acid was utilized as activation agent. Doctor blade method was employed to fabricate films of activated carbon on conductive or nonconductive glass substrates. Films were subsequently annealed at 70 0C for 30 minutes in air. According to XRD patterns, single phase of activated carbon was crystallized in thin film form. Carbon prepared from banana peels …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 14–25 Read article
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Stability Indicating HPLC Method for Drugs Indicated for Helicobacter Pylori-associated Ulcers
Abstract: Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Triple therapy regimen that comprises a proton pump inhibitor likes Omeprazole, antibiotics like Doxycycline and Tinidazole can be used for treatment of peptic ulceration which is caused by H. pylori. A validated HPLC method was developed as a stability-indicating HPLC method for these drugs and its impurities. New method overcame interference between Doxycycline and its epimer on achiral column by using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 28–46 Read article
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Determination of RP-HPLC Method for Safinamide: Its Bulk and Tablet Dosage Form
Abstract: A new method was established for estimation of Safinamide by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Safinamide by using Agilent C18 column (4.6×150 mm, 5 µ); flow rate was 1 ml/min, mobile phase ratio was Methnol, Acetonitril (60:40), pH 3 (pH was adjusted with orthophosphoric acid), detection wavelength was 235 nm. The instrument used was WATERS HPLC Auto Sampler, Separation module 2695, photo diode …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 1–6 Read article
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Quantitative Mass Balance Modelling for the Synthesis and Production of Ten High-Volume Insecticides
Abstract: This study presents a detailed quantitative mass balance analysis for the industrial synthesis and production of ten high-volume insecticides: acequinocyl, acetamiprid, acynonapyr, alpha-cypermethrin, benzpyrimoxan, bifenazate, bifenthrin, bistrifluron, broflanilide, and bromofos, focusing on material flows, process efficiencies, and environmental implications. These compounds, spanning diverse chemical classes like neonicotinoids, pyrethroids, and meta-diamides, are essential for crop protection but pose challenges due to resource-intensive syntheses and waste generation. For each insecticide, standardized manufacturing …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 36–55 Read article
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Novel Amino Silanes for Inhibition and Dissolution of Aldol Polymer for Caustic Tower in Cracker Plant
Abstract: Aldol polymer fouling in petrochemical plant is an undesirable process, which needs to be removed for increasing the efficiency of downstream process. In this paper, inhibition and dissolution efficiency of the aminopropyl trimethoxy silane (APTMS), aminopropyl triethoxy silane (APTES), sodium salt of aminopropyl trimethoxy silane (SS-APTMS), sodium salt of aminopropyl triethoxy silane (SS-APTES) were studied at different molar ratio of vinyl acetate (VA):amino alkoxy silane (antipolymerant). The sodium salt of …
Published in Journal of Petroleum Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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Synthesis and Characterization of Sustainable, Low-Cost, Biomass-Derived Carbon Films from Hevea Brasiliensis (Rubber) Wood for Environmentally Friendly Gas Sensors with Enhanced Selectivity and Sensitivity to Polar Vapors and Hazardous Gases
Abstract: Hevea brasiliensis (rubber) wood sawdust was utilized to fabricate carbon gas sensors for detecting 1000 ppm of ethanol, methanol, acetone, carbon dioxide, and ammonia gases. The carbon particles were prepared by phosphoric acid impregnation followed by thermal activation and then fabricated into films on conductive and non-conductive substrates using the doctor blade method. X-ray diffraction (XRD) analysis revealed distinct graphitic features with peaks at the (002) and (100) planes, indicating …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 22–36 Read article
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Synthesis of Novel Series of Coumarin Derivatives
Abstract: In a synthetic method similar to Knoevenagel reaction, 3-acetyl coumarin was prepared in the same way through a cyclization condensation reaction betweensalicylaldehyde and ethyl acetoacetate under basic condition using piperidine. Hence, 3-acetyl coumarin as a starting material was reacted with bromine in ether using a Lewis acid as a reactioncatalyst to produce the corresponding α–bromoaceyl cromen-2-one derivative. In application ofHantzsch synthesis, the reaction of α–bromoaceyl cromen-2-one with thioacetamide in ether …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 1, 2021 · pp. 1–8 Read article
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Preliminary Studies of the Effects of Some Extraction Methods/Procedures on the Yield and Physicochemical Properties of African Breadfruit Seed Oil (Treculia africana)
Abstract: African breadfruit seed oil (ABFSO) was extracted using traditional and solvent extraction methods. The procedure for the solvent extraction was varied as different solvent including; n-hexane, methanol, xylene and acetone were used in the extraction. The least oil yield (3.6%) was obtained from the traditional method while the highest was obtained using n-hexane in solvent extraction. The oil extracts which includes the traditional extract (TDE), n-hexane extract (N-HE), methanol extract …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 6, Issue 2, 2015 · pp. 23–30 Read article
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Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System
Abstract: Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography. Keywords: Derivatization, amino acid, chiral reagent, HPLCCite this Article Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 39–43 Read article