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125 articles for “Signal”
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Design and Implementation of Low Noise Power Low and High Speed Three Stage Comparator Using 16nm Technology
Abstract: To meet the demands of quicker operation and reduced noise levels, this study proposes a new CMOS Three-based comparator version. Efficiency may be significantly improved by comparing the suggested model to existing ones. This is so because the suggested comparator would improve the efficiency of the current amplifier design. The suggested model drives the input pairs of the regenerator and the amplified stage, making for a quicker comparator. The structure …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 2, 2023 · pp. 10–16 Read article
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Efficient Gabor Filter Design Using Verilog HDL with Multiplier-accumulator (MAC) Implementation
Abstract: This paper introduces a novel and enhanced Gabor filter design aimed at addressing the demands of image processing applications using the Verilog Hardware Description Language (HDL). Specifically, it leverages the Reconstruct Gabor filter technique to elevate the performance and quality of standard image outputs. The primary objective of this research endeavor is to simplify the study, conduct an in-depth analysis, and substantially enhance the design's efficiency, all while ensuring the …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 2, 2023 · pp. 40–46 Read article
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Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
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Literature of Green Architecture
Abstract: The term green architecture implies the use of environmental principles as the basis when designing buildings. In this perspective, the architecture of the future aims at synthesizing nature, technology, science, and even the imagination in the construction industry. The following paper explores green architecture on a generalized basis, which discusses its basic features, practices and the repercussions of green design on environmental sustainability. A key component of eco-architecture is to …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 47–53 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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Deciphering the Pathophysiology of Migraine: Understanding Trigeminovascular System Activity and the Importance of the Gut-Brain Axis
Abstract: Migraine, a prevalent and disabling neurological condition, manifests in distinct phases: premonitory, aura, headache, postdrome, and interictal. Being a primary contributor to adult disability, it presents a substantial economic challenge on a global scale. Even with extensive research spanning centuries, the complete grasp of its root causes continues to evade us. This intricate neurovascular disorder primarily involves local vasodilation of intracranial and extracerebral blood vessels, coupled with simultaneous stimulation of …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 50–61 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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A Comprehensive Review: Effectiveness Of Multi-Sensory Learning Strategies for Learning Disability Students
Abstract: A person's ability to learn new things can be severely hampered by a range of neurodevelopmental diseases known as difficulties with learning. Multisensory learning is an instructional strategy that offers learners multiple ways to perceive information through different sensory signals. The purpose of this review is to assess how learning disabilities, Dyslexia, Dysgraphia, and Dyscalculia can be treated with a multisensory learning approach. A thorough evaluation of past papers published …
Published in International Journal of Education Sciences · Vol. 1, Issue 2, 2024 · pp. 01–09 Read article
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Development and Implementation of Indoor Location-based Service in Museums Based on Bluetooth Low Energy Standard and Triangulation Algorithm
Abstract: Location-based services (LBS) in indoor locations are for providing information needed by users, and this information can be provided to users based on a Geofence. The most important component of location-based service systems is the Global Positioning System (GPS), which does not have the ability to determine the location in an indoor location. In this research, LBS Android software was developed for museums with the possibility of providing multimedia information …
Published in International Journal of Wireless Security and Networks · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Performance Evaluation of Adverse Atmospheric Effects on Free Space Optical Communication
Abstract: There is an increasing need for communication systems that can accommodate high bandwidth and quick data transfer rates in today's fast-paced technological environment. Free Space Optical (FSO) communication has become a very attractive technology to address these changing needs. FSO systems, which use license-free infrared beams, have a number of benefits, including strong bandwidth, immunity to interference, improved security, and small, light designs. FSO is used in many different applications, …
Published in International Journal of Solid State Innovations & Research · Vol. 2, Issue 1, 2024 · pp. 21–29 Read article
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Nanoyeast Supported on Silica Gel for The Continuous Flow Bioethanol Production
Abstract: Nanomaterials outperform their bulk counterparts. Yet, production of nanomaterials, especially, nanoyeast is a challenge and is an upcoming field. Yeast is a fungal strain that consumes carbohydrates (glucose, sucrose, molasses and the like) and produces bioethanol, a potential transportation fuel. Impregnation methods are well known in catalysis to yield nanomaterials via better dispersion. An attempt has been made to modulate the size of yeast to increase the efficiency of carbohydrate …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 1–7 Read article
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Raman Spectroscopy for The Determination of Relative Crystallinity of Carbon Fibers
Abstract: Analogous to X-ray diffraction technique, the light scattering technique discovered by Sir CV Raman has great potential in quantifying the crystallinity of new materials, like the highly crystalline pitch based carbon fibers (NX90 and NX100). For comparison the Raman spectra of polyacrylonitrile based carbon fibers (T700SC) were also recorded. From the Raman spectral analysis, it was found that the pitch based carbon fibers exhibit far far higher degree of crystallinity …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 30–38 Read article
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Automatic Power Switching Mains for Various Sources
Abstract: This project's major objective is to autonomously choose from four possible power sources—mains, generator, inverter, and solar—to guarantee a load's continuous power delivery. This is crucial due to the rising demand for electricity and the frequent power disruptions affecting industries, hospitals, and households. Establishing an alternative power source is imperative to address this issue. In this project, four switches are utilized to simulate the failure of individual power sources. Pressing …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 24–30 Read article
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Advancing Grid Integration: Maximum Power Point Tracking-Based Model Predictive Current Control Technique for Photovoltaic Systems
Abstract: Tracking a PV system's maximum power point is necessary as demand for grid-connected solar systems rises, regardless of utility demand. Since the PV system's output is D.C., a converter serving as a middleman between the PV system and the D.C. link capacitor is necessary to track the maximum power at all loads. Since the firing angle of the IGBT in the boost converter is between 0 and 1 at maximum …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 31–35 Read article
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Exploring the Efficiency of Leading and Lagging Indicators in Algorithmic Trading
Abstract: This paper details a comparison of the overall performance of leading and lagging technical indicators used in algorithmic trading over an extended period. While much of the prior research focuses on index price forecasting and some on statistical arbitrage derived from these predictive techniques, there is a scarcity of studies that assess and evaluate trading strategies. The strategies considered for the study were tested on historical data of the 50 …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 2, Issue 2, 2024 · pp. 8–18 Read article
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Practical studies in Vero cell and Human amnion cells for viral and stem cell applications
Abstract: Vero cells are one of the most popular mammalian continuous cells in molecular, cellular, and microbiological research. African green monkey kidneys are used to make these.One continuous cell line is the Vero cell line. This cell line is dependent on anchorage. Vero cells can be cultured in suspension because they are anchorage independent. Thought to be non-tumorigenic cells that came from a female Chlorocebus sabaeus Numerous viruses can infect vero …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article