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93 articles for “Molecular weight”
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Phenetic Analysis of Solanum melongena Accessions to Explore the Genetic Diversity by SDS-PAGE
Abstract: The present experimental work was conducted for the phenetic analysis among 40 accessions of Solanum melongena from different geographical areas of Pakistan. The interspecific variation was found among the accessions of S. melongena. The analysis of seed storage was done by SDS-PAGE to check their relationship. Electrophoretic data was documented by gel documentation system (Bio-Rad, USA), and analyzed by using quantity 1-D analysis software and dendogram constructed with 100% tolerance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 2, Issue 2, 2012 · pp. 21–34 Read article
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Homology Modeling and in silico Characterization of a Hypothetical Protein of Arabidopsis lyrata ssp. Lyrata
Abstract: Arabidopsis lyrata, a plant belonging to brassicaceae, is a model organism for studying evolutionary and ecological genetics. Most of the proteins of this plant have remained uncharacterized and their functional roles are still to be elucidated. In this investigation, we have attempted to characterize one such hypothetical protein in terms of its physico-chemical properties, secondary and tertiary structure features by in silico study. The protein was classified under glycoside hydrolase …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 2, 2013 · pp. 1–5 Read article
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Eye Is the Window of Brain – Does It Hold True in Case of Cerebral Sinovenous Thrombosis?
Abstract: Cortical sinovenous thrombosis is not an uncommon condition encountered in inpatient settings. This is a disease with high-risk outcomes and our present knowledge about its prevention and definitive treatment is meager. Physicians world over treat this condition with combination of antimicrobials, low-molecular-weight heparin (LMWH), other supportive measures as per situation and rarely with neurosurgical interventions, if required. Once the patient starts improving, the sinovenous thrombosis and subdural collection resolve along …
Published in Research and Reviews: A Journal of Medicine · Vol. 2, Issue 2, 2012 · pp. 12–15 Read article
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Techno-economical Analysis of Biodiesel Production using Castor Oil: An Indian Approach
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Biodiesel is an alternative biodegradable and nontoxic fuel, which is essentially free of sulphur and aromatics. It is usually produced by a trans-esterification reaction of vegetable or waste oil with a low molecular weight alcohol, such as ethanol and methanol. Industrially, the most common method for biodiesel production is a basic homogeneous reaction. Hence, this work presents the trans-esterification of castor …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 4, Issue 1, 2014 · pp. 22–31 Read article
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Protein-Tyrosine Phosphatase-1B (PTP-1B) Inhibitory Perspectives of Hydroxylated Chalcones: Exploration through Docking Studies
Abstract: The current research emphasized on exploring the Protein-Tyrosine Phosphatase-1 B (PTP-1B) inhibitory potentials of hydroxylated chalcone derivatives against PDB ID: 4I8N (PTP-1B in complex with an inhibitor [(4-{(2s)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl)sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid) by molecular docking approach using the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The current molecular docking analysis of some hydroxylated chalcone derivatives have presented a profound inhibition of the antidiabetic target PTP-1B by interacting with the amino acid residues …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 1, 2019 · pp. 4–8 Read article
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Intrinsic Viscosity of Stud Plant Mucilage (Dicerocaryum Zanguebarium): Polymeric Studies at Infinite Dilution.
Abstract: AbstractStudies on stud plant mucilage (SpM) showed that it constitute of galactose, mannose and xylose and it has a molecular weight of 500kDa. However, the behaviour of the polymer using intrinsic viscosity, in dilute regime, has not been explored. The research investigated the intrinsic viscosity of SpM in water, salt and sugar solutions. Salt solutions has poor solvent properties and hence reduced the intrinsic viscosity of SpM as opposed to …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 10, Issue 1, 2019 · pp. 28–39 Read article
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Pretreatment of Lignocellulosic Biomass for Bioethanol Production: A Brief Review
Abstract: AbstractNowadays, lignocellulosic materials have gained increased interest in research and special importance because of their reproducible and abundant nature. A large amount of lignocellulosic biomass can potentially be converted into different high value products including value added fine chemicals, bio-fuels, and cheap energy sources, enzyme production and microbial fermentation. It is chiefly composed of cellulose, a linear glucose polymer, hemicellulose, highly branched heteropolymer, and lignin, a very high molecular weight …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 5, Issue 2, 2016 · pp. 1–7 Read article
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Review on UV – Visible Spectroscopy and HPLC
Abstract: Like Fourier-transform infrared spectroscopy, UV-visible spectroscopy is used to determine the purity of pharmaceutical compounds. Many substances have chromospheres, which absorb certain wavelengths of ultraviolet or visible light. Using the Beer–Lambert equation, the absorption of spectra obtained from these samples at given wavelengths can be directly related to the sample concentration. Normally, UV and UV-visible spectra are recorded at high and low pH, and the results of both are compared …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 1, 2022 · pp. 43–54 Read article
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Polyphenol Recovery Using Nanofiltration and Tight Ultrafiltration: A Review
Abstract: A viable strategy to lessen the environmental contamination of numerous by-products is pressuredriven membrane-based technology. The recovery, isolation, and separation of polyphenols from such by-products has recently received attention due to the growing interest in natural chemicals having biological activity. The potential to recover phenolics from various kinds of by-products has been observed particularly for tight filtration process and nanofiltration membranes. These membranes' productivity and ability to separate substances are …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 3, 2022 · pp. 31–35 Read article
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“High Melatonin Milk”- Milk with Intrinsic Health Benefit
Abstract: Melatonin C13H16N2O2 (molecular weight: 232) or N-acetyl-5-methoxytryptamine, is chemically an indoleamine and derived from the essential amino acid tryptophan. It is a hormone and due to secretion from pineal gland, it is also called as active pineal factor. Its IUPAC name is N-[2-(5-methoxy-1H-indol-3-yl)ethyl] acetamide. The indole ring acts as the chromophore showing maximum absorbance at 223 nm, and the functional groups contribute to its fluorescence property. Lerner et al. 1959 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 13–16 Read article
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In silico Characterisation of Proteins of Glycyrrhiza glabra and Assessment of Nanoparticle Synthesising Ability of Closely Related Plant Species
Abstract: The main aim of the study is to analyse the proteins of Glycyrrhiza glabra using various bioinformatics tools. The proteins were structurally as well as functionally characterized using tools like ProtParam, SOPMA and SOSUI. NAD(P)H quinone oxidoreductase protein in Glycyrrhiza glabra was selected for evaluation and protein BLAST was performed. Primary structure prediction was performed to evaluate physical and chemical characteristics of proteins viz., Molecular weight, pI, etc. The secondary …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 97–103 Read article
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Impacts of Phthalate Plasticisers—An Emerging Issues and Concerns
Abstract: Phthalates or phthalic acid esters are the esters of phthalic anhydride used to increase the flexibility and durability of plastic products including polyvinyl chloride (PVC). Based on the molecular weight, phthalates are grouped into low and high phthalates that shows diverse applications and different mode of toxicity in various animals. The enormous production and widespread applications allow them to exist in all environments including air, water, and soil; in solid, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 9, Issue 2-3, 2020 · pp. 14–49 Read article
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Current Prospective of NLCs in Parkinson’s Disease: An Outlook
Abstract: Parkinson's disease (PD) is 2nd most a neuro-degenerative disorder of the central nervous system affecting 7–10 million people of worldwide as the report of WHO 2014. It occurs due to the death of dopamine-generating cells in the substantia nigra, a region of the midbrain. It is characterized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole Hydrochloride is a drug of choice …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 18–29 Read article
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Assessment and In Vitro Studies of Potent Amylase Inhibitor from Different Plant Species
Abstract: Flavonoids are naturally occurring compounds widely distributed in plants, which have hypoglycemic potential. Amylase inhibitors belong to flavonoids that block amylases which are involved in hydrolyzing the carbohydrates to yield low molecular weight dextrin and sugars. Inhibition of α-amylase along with α-glucosidase can significantly reduce the post-prandial increase of blood glucose and can be an important strategy in the control of blood glucose level in the type-2 diabetic patients. In …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 1–6 Read article
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QSAR Studies on Schiff Bases of Pyrrole-2-Carboxaldehyde for Antimicrobial Activity
Abstract: Pyrrole and Schiff bases are therapeutically significant organic moieties. QSAR (Quantitative structure-activity relationship) studies of thirteen pyrrole-2-carboxyaldehyde Schiff bases have been described for antimicrobial activity against S. epidermidis, E. coli and S. aureus. Described 2D QSAR models are statistically significant models with good fitting ability and robustness. The Q2 value is more than 0.5 for all discussed models which confirms the internal predictive power of the derived QSAR equations. Molecular …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 3, 2016 · pp. 1–8 Read article
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HPLC Method Development and Validation for Simultaneous Estimation of Succinic Acid and Succinylmonocholine in Succinylcholine Chloride Injection
Abstract: Succinylcholine chloride injection USP is a sterile, non-pyrogenic solution to be used as a short-acting, depolarizing, skeletal muscle relaxant. The injection is administered as IM or IV use. Succinylcholine chloride, USP is chemically designated C14H30N2O4 and its molecular weight is 290.399. Succinylcholine chloride has three known impurities: (1) Doublet peak, (2) Succinic acid and (3) Succinylmonocholine chloride. Out of these impurities, succinic acid and succinylmonocholine chloride are degradation impurities, whereas …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 52–60 Read article
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Production and Partial Purification of Tannase from Bacillus sp.
Abstract: Micro-organisms tannase is industrial-important enzymatic enzymes can, through oxidation with secondary metabolites including such tannins, catalyze that production of Gallic acid or glucose. Tannase are commonly used in the production, drink, food processing and brewing and chemical industries. Tannic acid with low-value agro-industrial waste was also commonly used in manufacturing besides tannase production. Tannase also have huge 124–310 KDa variety with molecular weights as well as a great deal with …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 2, 2023 · pp. 42–51 Read article
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Versatile Application of Tannase: A Review
Abstract: Micro - organisms tannase is industrial-important enzymatic enzymes can, through oxidation with secondary metabolites including such tannins, catalyze that production of Gallic acid or glucose. Tannase are commonly used in the production, drink, food processing and brewing and chemical industries. Tannic acid with low-value agroindustrial waste was also commonly used in manufacturing besides tannase production. Tannase also have huge 124-310 KDa variety with molecular weights as well as a great …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 2, 2023 · pp. 13–17 Read article
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An Overview of Anticoagulants in Treatment of Thrombosis and Related Disorders: A review
Abstract: With the increasing ageing of population, clinicians are encountering patients with atrial fibrillation and venous thromboembolism who require anticoagulant therapy to prevent stroke and systemic embolism. Due to its high prevalence and unfavorable results, the treatment of thromboembolic disease has become a clinically important area. Traditional anticoagulants such as heparin, low molecular weight heparin, and warfarin have been used to prevent and treat venous and arterial thrombosis. However, bleeding problems, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 1–8 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article