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294 articles for “Favorable”
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Securix: An Open-Source Security-based Linux Distribution for Novice Cyber Security Enthusiasts
Abstract: In the ever-evolving field of cybersecurity, the need for accessible and user-friendly tools in favor of beginner users has never been greater. The existing ethical hacking-related operating systems, while powerful, often overwhelm beginners with their complexity. The main objective of this project is to bridge the gap by providing an operating system for novice cyber enthusiasts looking to explore the world of ethical hacking and security. The proposed operating system …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Exploring the Development of AI Models Using Open-Source Tools to Predict Patient Outcomes and Optimize Treatment Plans
Abstract: Integrating artificial intelligence (AI) into healthcare offers a transformative opportunity to enhance patient care and clinical decision-making. Through the use of predictive analytics, AI can significantly enhance the accuracy of outcome predictions and assist in developing personalized treatment plans that cater to each patient’s specific needs. This paper delves into the development of AI models using open-source tools, which are increasingly favored for their accessibility, collaborative nature, and capacity for …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 37–49 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Assessing the Diversity of Migratory Fishes in the Shivnath River, Chhattisgarh, India
Abstract: The Shivnath River, a major tributary of the Mahanadi River in Chhattisgarh, India, is home to various migratory fish species. These fish are vital to the river’s ecosystem and provide important sources of income and food for local communities. This study looks at the diversity, distribution, and conservation status of these migratory fish species in the Shivnath River. Through extensive field surveys, researchers identified 10 migratory fish species in the …
Published in Research & Reviews : Journal of Ecology · Vol. 14, Issue 1, 2025 · pp. 45–51 Read article
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Deformation and Densification Behaviour of Sintered Aluminium Alloy and Chromium Carbide Metal Matrix Preforms
Abstract: This paper presents comprehensive experimental results focused on the deformation and densification behavior of sintered AA2618 - 2% Cr3C2 metal matrix preforms. The study specifically examines preforms with varying aspect ratios subjected to a cold upsetting process. To create the powder preforms, an initial theoretical density of 89% was achieved using a cylindrical die on a 600 kN hydraulic press. The sintering process was conducted in an electric muffle furnace, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 125–131 Read article
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Development of Polymer-based Mulch Films for Disease Suppression
Abstract: Gerbera jamesonii [Gerbera daisy) is a popular flowering plant susceptible to various microbial diseases. This paper explores disease control strategies for gerberas, focusing on the potential of novel polymer-based mulch films. Conventional mulching practices offer benefits in gerbera cultivation, including weed suppression that helps control pathogens. However, limitations associated with traditional mulch materials necessitate exploring alternative solutions. This study investigates the development of biodegradable polymer-based mulch films specifically designed for …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 856–863 Read article
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Enhancing Sustainability in Building Design: Optimizing Energy Efficiency and Reducing Carbon Footprint Using BIM Tools and Polymer Matrix Composites
Abstract: Sustainable construction is an imperative that transcends the immediate and future horizons of the construction industry, propelled by the escalating recognition of the sector's ecological impact. Building Information Modelling (BIM) has firmly established itself as a pivotal instrument within the industry due to its unique capacity to seamlessly merge the physical and analytical dimensions of construction, thereby ushering in transformative practices. This research paper offers an all-encompassing exploration of the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 181–189 Read article
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Assessing the Clinical Efficacy and Safety of Semaglutide: A Comprehensive Study
Abstract: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has emerged as a versatile therapeutic agent with significant potential in managing a range of diseases. Extensive research has demonstrated its efficacy in treating obesity, type 1 and type 2 diabetes, and even neurodegenerative disorders like Parkinson’s disease. This comprehensive review examines the principal outcomes derived from clinical trials that incorporate semaglutide alongside other GLP-1 agonists, with particular emphasis on the mechanisms underlying …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 96–104 Read article
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Effect of Radiation Dose, Dose Rate and Annealing Temperature on Edible Potato Starch by Spectroscopic Methods
Abstract: Potato starch (PS) is a favorite food choice in different forms. During its storage and applications the PS is exposed to different radiations. In the present study the authors attempt to compare radiation effects (gamma and Electron beam of same radiation dose) in PS by Electron spin resonance (ESR) and Fourier transform infrared (FTIR) methods. ESR spectra of gamma irradiated PS appeared to have resolved shapes than the electron beam …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 198–209 Read article
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Understanding Food Spoilage: Mechanisms, Shelf-Life Determination, and Safety Standards
Abstract: Food spoilage poses significant challenges to the global food industry, impacting both food safety and economic sustainability. The main causes of food quality deterioration are microbial and non-microbial spoiling. Microbial spoilage primarily results from the activity of bacteria, yeasts, and molds, which thrive under favorable environmental conditions. These microorganisms can lead to food poisoning and spoilage through the production of off-flavors, discoloration, slime formation, and the accumulation of harmful toxins. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 6–9 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Computational Analysis of Tinospora Cordifolia Phytochemicals as Potential Inhibitors of BRCA1-BRCT Domain Interaction in Breast Cancer
Abstract: Breast cancer is a leading cause of cancer-related deaths worldwide, accounting for a significant proportion of mortality rates among women. Despite current therapeutic approaches, the disease remains characterized by molecular heterogeneity, making it challenging to develop effective treatments. This study explores the potential of Tinospora cordifolia, a medicinal plant, in breast cancer therapy. Guduchi, scientifically known as Tinospora cordifolia, boasts a centuries-long history of use in traditional medicine, with a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 27–37 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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A GIS and MCDA Framework for Land Suitability Analysis in Sustainable Agriculture
Abstract: This study examines land suitability for sustainable agriculture by integrating Geographic Information Systems (GIS) and Multi-Criteria Decision Analysis (MCDA) as tools to optimize agricultural planning. Sustainable agricultural practices are increasingly critical to meet global food demands without depleting essential land resources. This research focuses on assessing specific parameters that determine the agricultural viability of land, including soil characteristics, topography, climatic conditions, and water availability. These criteria are integral to understanding …
Published in International Journal of Land · Vol. 1, Issue 2, 2024 · pp. 30–34 Read article
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Advanced Composite Materials for Electric Vehicle Charging Stations: A Comprehensive Study
Abstract: EV chargers are thought to be a major determinant in the adoption of EVs in present transport systems. The performance and durability of these charging stations highly depend on the materials applied in the construction of these charging stations because these materials should be very reliable, durable and efficient. The current paper reviews the current literature on advanced composite materials relevant in the construction of the EV charge station. Recognitions …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 401–415 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Climate Change and the Spread of Pathogens: Implications for Public Health
Abstract: Climate change plays a significant role in the spread of infectious diseases by shifting how pathogens behave, affecting how vulnerable hosts are, and changing the way diseases are transmitted.Rising global temperatures, changing precipitation levels, and extreme weather events are accelerating the spread of bacteria, viruses, fungi, and parasites, increasing the risk of outbreaks worldwide. Warmer conditions favor the survival and expansion of vector-borne diseases such as malaria, dengue, and Zika …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 1–5 Read article