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115 articles for “Diabetic complications”
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Hydroxylated Chalcone Derivatives as Future Aldose Reductase Inhibitors: Discovery through Docking Technique
Abstract: The research endeavors molecular docking assisted exploration of ALR inhibitory perspectives of some B-ring substituted hydroxyl group (A-ring) containing chalcone compounds against human aldose reductase in complex with NADP+ and the inhibitor IDD594 (PDB ID: 1US0) by utilizing the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present investigation immensely focused on the human aldose reductase inhibitory perspectives of some hydroxylated chalcone compounds. The inhibition of the enzyme by …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 8–12 Read article
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Comparison of Prescribing Pattern of Anti-hypertensive Drugs and the Level of Control Achieved in Type 2 Diabetes Patients between Primary and Tertiary Care Hospitals
Abstract: Hypertension is a common co-morbidity of diabetes affecting majority of people with diabetes, also a major risk factor for coronary vascular disease and microvascular complications such as retinopathy and nephropathy. To compare prescribing pattern of anti-hypertensive drugs and the level of control of hypertension achieved in type 2 diabetes patients in primary and tertiary care hospitals. Fifty patients each with type 2 diabetes and hypertension (fulfilling JNC 7 criteria for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 2, 2014 · pp. 1–4 Read article
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Identification of Diabetic Foot Ulcer by Using Filter and Pixel Classification Methods
Abstract: Ulceration of the foot in diabetes is common and disabling and frequently leads to amputation of the leg. Mortality is high and healed ulcers often recur. The pathogenesis of foot ulceration is complex, clinical presentation variable, and management requires early expert assessment. Interventions should be directed at infection, peripheral ischaemia, and abnormal pressure-loading caused by peripheral neuropathy and limited joint mobility. Despite treatment, ulcers readily become chronic wounds. Diabetic foot …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 1, 2015 · pp. 22–31 Read article
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Recombinant Insulin
Abstract: Recombinant insulin, a revolutionary product of biotechnology, has transformed the landscape of diabetes treatment. Developed through genetic engineering techniques, recombinant insulin offers a safer, more consistent alternative to traditional animal-derived insulin. Its production involves the insertion of the human insulin gene into host organisms such as Escherichia coli or Saccharomyces cerevisiae, which serve as efficient factories for insulin synthesis. Recombinant insulin is used to treat diabetic patients who are allergic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 39–43 Read article
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Evaluation of Medication Adherence in Patients with Type 2 Diabetes Mellitus: A Mixed- Methods Approach
Abstract: Background: Medication adherence refers to how closely an individual follows the prescribed medication regimen. It is essential for achieving desired therapeutic outcomes and improving patient health. Inadequate adherence can result in the deterioration of health conditions, higher mortality rates, and increased healthcare expenses. Diabetes mellitus, being a chronic condition, demands ongoing medical care not only to prevent the onset of serious complications but also to manage them effectively once they …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–35 Read article
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Diabetes Risk & Al Nutrition Assistant
Abstract: The rising prevalence of diabetes mellitus has emerged as a major global health challenge. Early identification of individuals at risk, combined with personalized lifestyle-based interventions, can significantly reduce future complications. This study presents an AI-driven Nutrition Assistant integrated with a Diabetes Risk Prediction model. The system uses a machine learning classification approach to estimate the likelihood of diabetes based on clinical and nutritional factors, including body mass index, glucose levels, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 31–38 Read article
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Overview of Diabetic Neuropathy: A Comprehensive Examination
Abstract: Abstract: India has earned the unfortunate distinction of being the global epicenter for diabetes, with an alarming projection of 109 million individuals expected to be afflicted by the condition by 2035The global influence of diabetic neuropathy is significant, with an estimated 132 million individuals affected as of 2010, constituting roughly 1.9% of the global populace. Notably, within the diabetic population, there exists a significantly heightened prevalence The prevalence of sensory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 26–36 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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IoT-Based Diabetes Management: Advancements and Challenges in Healthcare
Abstract: The integration of the Internet of Things (IoT) into healthcare has revolutionized disease management by enabling real-time monitoring, data analysis, and proactive interventions. This paper explores how IoT applications can significantly enhance diabetes management by providing sustainable and innovative healthcare solutions. Leveraging IoT-enabled devices such as Continuous Glucose Monitoring (CGM) systems, smart wearables, and remote patient monitoring tools, diabetes care can be personalized and made more efficient, reducing long-term complications. …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Covid-19 Associated Mucormycosis: Urgency To Reconsider The Uncontrolled Use Of Prophylactic Drugs
Abstract: Mucormycosis, a lethal mycosis, has affected hundreds of COVID-19 sufferers in India. Mucormycosis, previously known as zygomycosis, is due to the diverse fungi that belong to the family "Mucorales." These molds are normally determined in soil, air, and damp partitions and often colonize oral mucosa, nose, paranasal sinuses, and throat. The pathophysiological results of diabetes mixed with the intense inflammatory surge in COVID-19 and steroid remedy weaken a person's immunity …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 3, 2021 · pp. 12–17 Read article
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Predicting Eye Blindness by Detecting Exudates in the Retina of Human Eye
Abstract: Diabetic retinopathy is a condition where a person suffering from diabetes starts to loosen his vision slowly as the severity of the disease increases gradually. We can diagnose this condition by the fundus image of the retina of the human eye; although it is very complicated for doctors to predict the conditions just by seeing the fundus images. By detecting diabetic retinopathy at the earliest, we can protect patients from …
Published in Journal of Computer Technology & Applications · Vol. 12, Issue 1, 2021 · pp. 17–23 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article
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Study on Vitamin D Deficiency and Hypocalcemia in Chronic Kidney Disease Patients in a Tertiary Care Hospital: A Single-Centered Study
Abstract: Background: Patients with chronic kidney disease (CKD) suffers from multiple comorbidities such as hypertension, diabetes mellitus, coronary artery disease and pyelonephritis. The most commonly accompanied complications are Vitamin D deficiency (VDD) and hypocalcemia that require multiple medications. This study evaluated the number of patients suffering from VDD and hypocalcemia and also analysed the utilization pattern of Calcium and Vitamin D supplements in CKD patients. Objectives: To evaluate the number of …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 3, 2019 · pp. 20–24 Read article
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Regenerative Endodontics: Nano 3D scaffolds as Dental Materials and Stem Cells for Dental Tissue Regeneration
Abstract: In dentistry, for maintaining any tissue in a healthy state, focus is on prevention, treatment and repair of the diseased tissue. Current treatments for diseases of tooth structures rely on the use of classical endodontic procedures which in some cases are limited success rate. The use of stem cells in regenerative therapies have been shown to have promising applications in various debilitating diseases like neurodegenerative disease, diabetes, cancer and dental …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 14–23 Read article
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Diabetes Risk Prediction from Survey Data Using Machine Learning Algorithms
Abstract: Diabetes mellitus represents one of the most significant global health challenges, affecting millions worldwide and leading to severe complications if left undiagnosed or poorly managed. Early detection and risk assessment are crucial for preventing the progression of this chronic condition. This research presents a comprehensive machine learning approach for predicting diabetes risk using survey-based health parameters. The study implements and compares four prominent classification algorithms: Logistic Regression, K-Nearest Neighbors (KNN), …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 · pp. 1–8 Read article
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The Epidemiology of Risk Factors and Complications of Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: AbstractIn most of the developed countries non alcoholic fatty liver disease (NAFLD) is the common chronic lover disease mainly due to obesity. The disease increases liver related morbidity and mortality, and often increases the risk for other comorbidities, such as type 2 daibetes and cardiovascular disease. In NAFLD cardiovascular diseases are the major causes of death and only some people develop fibrosis and liver related complications. The prevalence of non …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 9–13 Read article
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Childhood Obesity: From Determinants to Clinical Management strategies
Abstract: Childhood obesity is one of the major global health problems in whole world, with a dramatic increase in prevalence over the recent few decades. Obesity associated with very serious long term health complications and sometimes very serious complications, such as metabolic disorders, cardiovascular, neurological, renal and psychological disorders. There are various factors such as genetic, environmental, behavioural, and socio-economic factors are some key player in the pathogenesis of obesity. In …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 45–53 Read article
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Role of Nitric Oxide in Platelets of Breast Carcinoma
Abstract: Breast cancer is a disease of multifactorial origin; it is seen frequently in women of older age, having family history, affluent society, late age of marriage and first childbirth, early menarche, late menopause, and nulliparity. Oxidative stress results when balance between reactive oxygen species (ROS) production and antioxidant defence is lost which result in mutations, sister chromatid exchanges, cytotoxicity, carcinogenesis etc. Clinical, experimental and epidemiological studies suggest that free radicals …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 25–29 Read article
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Modeling of Patient of Type 1 Diabetes for Blood Glucose Control
Abstract: The recent development in the insulin delivery system is the automatic one. The blood glucose levels are controlled by the feedback loop. The initial success with the simple models in normalizing blood glucose level led to the improvement of the devices including variety of control system. The insulin delivery system to diabetic is a tedious job and doesn’t ensure proper performance and leads to various complications if the delivery of …
Published in Journal of Microelectronics and Solid State Devices · Vol. 3, Issue 1, 2016 · pp. 30–35 Read article