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296 articles for “Clinical Practice”
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An Open Label Randomized Comparative Clinical Study of Safoof-e-Mohazzil versus Atorvastatin in the Cases of Fart-e-Tadassum-Fid-Dam (Primary Hyperlipidaemia)
Abstract: Hyperlipidaemia (Fart-e-Tadassum-Fid-Dam) is a common metabolic disease seen in clinical practice. It is mentioned that increased lipid level is associated with the pathogenesis of atherosclerosis. Theory of hyperlipidaemia meets similarly on the basis of etiology, presentation, complications, patho-physiology and non-pharmacological management with Saman-e-mufrit (obesity). Therefore, it is an important need to provide safe and effective drug from Unani system of medicine for the long term management of hyperlipidaemia. In the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2018 · pp. 6–12 Read article
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Use of the Computer Statistics in Oncology
Abstract: Currently, the use of computer statistics and computer statistical modeling in oncology for obtaining an accurate diagnosis, determination of the choice of treatment method and its correction in the process of ongoing treatment, prediction of the outcome of the disease, and evaluation of the effectiveness of the chosen treatment tactics is a decisive factor. The use of computer statistics, based on an adapted scientific and statistical package of the SSP …
Published in Research & Reviews : Journal of Statistics Read article
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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Speech Therapy in the Digital Age: Telepractice and Remote Interventions
Abstract: In the digital age, advancements in technology have revolutionized various aspects of healthcare, including speech therapy. This study explores the emergence and evolution of telepractice and remote interventions in speech therapy. Telepractice, interchangeably labelled as teletherapy or telehealth, denotes providing speech therapy services remotely using telecommunication technology. Its incorporation into speech therapy has broadened service accessibility, notably benefiting underserved or remote locales. Moreover, it has ensured uninterrupted care delivery during …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 42–46 Read article
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Role of Topical Onion Extract in Scar Management at Donor Site
Abstract: Scarring is commonly caused by an imbalance between collagen synthesis and degradation. One promising approach to mitigate scar formation involves the use of onion extract, known for its ability to inhibit fibroblast activity, which plays a key role in the development of scars. Despite the widespread use of onion extract in various commercial scar treatment products, the exact molecular mechanisms through which it exerts its scar-reducing effects remain unclear.This study …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 7–11 Read article
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Clinical study of ERAS programs for chronic anal diseases
Abstract: Background: ERAS protocols were implemented for the management of chronic anal diseases in our clinical setting.Patients and Methods: The clinical outcomes of these ERAS programs were systematically analyzed.Results: Our study revealed significant improvements with the implemented ERAS protocols. Specifically, the average time for healing with these protocols was 7.9±0.76 days, notably shorter compared to the previous standard protocols which averaged 14.3±0.4 days. Moreover, there was a marked reduction in postoperative …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 39–43 Read article
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Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Advancements in AI-Driven Diagnostics for Dental Health: A Comprehensive Review
Abstract: Dental diseases, also known as oral diseases or dental conditions, encompass a range of health problems affecting the teeth, gums, mouth, and associated structures. These conditions can lead to pain, discomfort, and severe complications if left untreated. Early detection and accurate diagnosis are crucial for effective treatment and prevention of further complications. This comprehensive literature review aims to identify common dental problems such as Tooth Decay (Cavities), Gingivitis, Periodontitis, and …
Published in Current Trends in Signal Processing · Vol. 14, Issue 2, 2024 · pp. 1–7 Read article
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Early Autism Diagnosis: Machine Learning Models and Their Effectiveness
Abstract: Diagnosis is of utmost importance for timely intervention and support. However, traditional diagnosis methods, which are based on subjective assessment, are delayed. This project explores the role that machine learning techniques might play in enhancing the accuracy and effectiveness of ASD detection. Several state-of-the-art classification algorithms were benchmarked using a dataset from Kaggle. Logistic Regression, XG Boost, Random Forest, Decision Tree, and Gradient Boosting were taken into consideration. Other performance …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 2, 2024 Read article
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Effectiveness of Twill Technique Vs Endotracheal Tube Holder on ETT Securement: A Comparative Study
Abstract: Endotracheal intubation is an urgent procedure which is performed on patients who are unconscious and can’t breathe by their own. Endotracheal Intubation keeps an airway open and helps to prevent chocking. When the patient is intubated, maintaining the endotracheal tube placement is essential. In case Endotracheal Tube is not secured, even basic nursing management can cause tubing slippage which is a major factor in causing airway trauma or injuries Aim: …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 39–47 Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Evaluate and Compare the Effect of Water of Different Hardness Levels on the Surface Irregularity in 3 Different Heat-Polymerized Denture Base Resins
Abstract: This study aimed to evaluate and compare the effect of water with varying hardness levels on the surface irregularity of three different heat-polymerized denture base resins. The hardness of water used in dental applications has been shown to influence the properties of dental materials, including denture base resins. In this study, three commonly used heat-polymerized denture base resins were subjected to immersion in water with different hardness levels. The surface …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 130–136 Read article
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Nanotechnology in Medical Applications: A Study
Abstract: In the field of medicine, nanotechnology has a wide range of applications that are both transformational and expansive. These apps provide solutions which have an opportunity to significantly enhance the outcomes of treatment and to provide better care for patients. The potential benefits are enormous, ranging from the delivery of drugs in a targeted manner to the development of sophisticated diagnostics and regenerative medicine. The incorporation of nanotechnology into clinical …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 1–11 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Clinical Profiles of Patients Presenting with Hypoglycemia in Emergency Department of Bir Hospital
Abstract: Hypoglycemia stands as a primary reason for visits to the Emergency Department (ED), ranking high among the most frequent and easily avoidable hormonal emergencies. The aim of this research is to investigate the occurrence of hypoglycemia and identify its underlying causes. As the number of diabetes cases rises, along with different methods of tightly managing blood sugar levels, the likelihood of hypoglycemia also increases. Given that extended periods of hypoglycemia …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 19–39 Read article
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Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article