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1964 articles for “as a result of which” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Quantitative Estimation of the Total Flavonoid Contents of Anogeissus pendula Stem
Abstract: Flavonoids are the typical secondary metabolites contents which are very useful in the plants as well as for human beings. They are one of the sources of several kinds of biological activity in the stem as well as in other part of the plants. These flavonoids are the typical antioxidants as well as they are used in inflammation; they are the typical antimicrobial, they have well distribution in the whole …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 55–57 Read article
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Analysis of Docking Study on Protein Neprilysin (Neutral Endopeptidase) Inhibition for Anti-aging Treatment by Aloe Emodin and Aloe Emodin Carbonyl Derivative
Abstract: Attempts were made to perform comparative docking study of Aloe emodin and its derivative on Neprilysin (PDB code: 1R1J) by using VLife MDS software to ascertain the activity of both. From all the interactions (Hydrogen bond and vander waals) it was observed that, the common amino acids which interacts with the common ligand were ASN542A, ALA543A, ARG102A, ASN542A, VAL580A. The result showed that the AEC (–1790.15 KCal) showed high total …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 3, 2014 · pp. 6–11 Read article
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GC-MS Analysis of Boerhavia diffusa Linn. Whole Plant Extracts: An Ethno-medicinal Plant
Abstract: In the present investigation, phytochemical compounds and GC-MS analysis of Boerhavia diffusa whole plant was studied, and presence of phytochemical compounds was screened by qualitative method. The results confirmed the presence of phytochemicals namely terpenoids, saponin, flavonoids, cardiac glycosides, phlobatannins and tannin. In GC-MS analysis, 42 phytochemical compounds were identified in the methanol extract of Boerhavia diffusa, the components were identified by comparing their relation indices and mass spectra fragmentation …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 1, 2018 · pp. 7–12 Read article
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Management of Patellar Tendonitis with Polyherbal Ayurveda Formulation
Abstract: Patellar tendonitis or Jumper’s knee is the commonest observed tendon injury amongst sport persons; the disease occurs due to acute or chronic injury during repetitive jumping or running. Patella tendon (ligament) is extremely strong that connects patella to tibia. The tendon receives excessive wear and tear during jumping and stabilising lending. The tendon receives stress in sports persons and athletes involved in different activities of jumping or changing direction frequently. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 1, 2019 · pp. 4–9 Read article
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Antibacterial Activities of Crude Extract from Infected Cocoa Against Abscess Forming Bacteria
Abstract: In this study, the antibacterial activity of crude phytoalexin extracted from matured cocoa pod against abscess forming bacteria was investigated. The crude phytolexin was extracted using redistilled dichloromethane after five days of post infection. Different concentrations (50, 100, 150 and 200 mg/ml) of the extract were tested against abscess forming bacteria namely; Escherichia coli, Staphylococcus aureus, Klebsiella Pneumoniae, Pseudomonas aeruginosa and Enterococcus faecium using paper disc and agar diffusion methods. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 2, Issue 3, 2015 · pp. 21–27 Read article
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Determination of the Antidiabetic Drug Miglitol in Pharmaceuticals by Ultra-Performance Liquid Chromatography
Abstract: Miglitol (MGL) is a drug used in the treatment of type-2 diabetes mellitus. A new analytical method employing ultra-performance liquid chromatography (UPLC) with UV-detection is presented for the determination of MGL in bulk drug and tablet forms. Analysis was performed in less than 3 min in isocratic mode on a reversed phase BEH C18 (100 mm × 2.1 mm; 1.7 µm particle size) column using phosphate buffer of pH 3.7-acetonitrile …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 2, 2018 · pp. 11–26 Read article
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Virtual Screening of Novel 2-substituted -5-hydroxy-1- (2-methyl-3-morpholinopropyl)-1H-indole-3- carboxamide Derivatives for Estrogen Receptor alpha in AF-2 domain for effective Anticancer Treatment
Abstract: Present manuscript describes designing of novel 2-substituted -5-hydroxy-1-(2-methyl-3- morpholinopropyl)-1H-indole-3-carboxamide derivatives as specific ERα modulators, discuss the selection criteria for 1ERR, several interactions between the ligand and the amino acid residues that would probably elicit fruitful modulation of the receptor. Accordingly, a ligand was observed to yield Gscore of -10.016 which was found comparable with the standard ligand Raloxifene (-11.869). The present work has been designed to discover some novel 2-substituted …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 31–55 Read article
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A Study and Report on the Role of Clinical Pharmacy Services Provided by the Doctor of Pharmacy in the Management of Thyroid Disorders (Hyperthyroidism and Hypothyroidism) to a Tertiary Care Hospital
Abstract: Thyroid hormones affect the function of virtually every organ system. In children, thyroid hormone is critical for normal growth and development but in adults, the main role of these thyroid hormones is to maintain stability. The main thyroid hormones which play such an important are the Thyroxine (T4) and Triiodothyronine (T3) hormones. Hence, Thyroid disorders encompass a variety of disease states affecting thyroid hormone production or secretion that result in …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 25–38 Read article
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Fabrication and Drilling Characterization of Hemp & Grewia-Optiva Hybrid Composite and Comparison with ANN Model
Abstract: In recent days the use of natural fibers has increased over synthetic fibers due to various advantages. The alkali treatment for these natural fibers further improves the adhesion between fiber and matrix and greatly enhances the mechanical properties of the composite. The present study involves the fabrication of a hybrid composite using the alkali-treated (5% NaOH concentration) natural fibers – Hemp &Grewia-optiva as reinforcement material and epoxy as a matrix …
Published in Journal of Polymer & Composites Read article
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Impact of I/Q Imbalance Due to Gain and Phase Mismatches on IRR, Image Leakage, Constellation Distortion, SNR and BER in OFDM Systems
Abstract: Due to its great spectral efficiency and resilience to multipath fading, orthogonal frequency division multiplexing, or OFDM, has become a popular modulation technique in contemporary wireless communication systems. Reliable OFDM reception depends on accurate channel estimate, and methods like Least Squares (LS) and Minimum Mean Square Error (MMSE) estimation are frequently used to make up for channel impairments. However, despite effective channel estimation, practical receiver performance can still be degraded …
Published in International Journal of Microwave Engineering and Technology · Vol. 12, Issue 2, 2026 Read article
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A Comparative Study of K-Means, DBSCAN, and Hierarchical Clustering for Content Segmentation in Netflix Movies and TV Shows
Abstract: Over-the-top (OTT) platforms like Netflix offer a vast and diverse range of movies as well as television programs, resulting in a difficult task of content organization. The unsupervised machine learning technique of clustering is an efficient approach to organizing these OTT platforms, as this technique helps in the grouping of content on the basis of their similar semantics, i.e., without using any labeled data. The study explores the use of …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 2, 2026 · pp. 9–16 Read article
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Real-Time YOLOv8l Contraband Detection in X- Ray Security Screening with Automated Identification of Weapons and Hazardous Objects for Threat Alerting
Abstract: A real-time contraband detection system based on YOLOv8l has been proposed for use in very high security installations, such as airports and public screening facilities. The contraband detection system has been trained with curated X-ray contraband datasets containing twelve different object types like firearms, knives, bullets, etc., with the datasets having been constructed to provide an equal number of examples for each object class to support robust detection. The methodology …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 13, Issue 3, 2026 Read article
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Reliability-Aware Multimodal Sentiment Analysis Using Speech, Visual and Textual Signals: A CMU-MOSEI Benchmark Re-analysis
Abstract: Multimodal sentiment analysis integrates linguistic, acoustic, and visual cues, but reported gains often assume that every modality is present and equally reliable. This study develops a reliability-aware multimodal sentiment-analysis framework and performs a quantitative re-analysis of verified CMU- MOSEI benchmark results to determine how modality availability changes predictive performance. The conceptual architecture combines text, acoustic, and visual encoders with quality-conditioned gated fusion. For the quantitative component, complete- and missing-modality results …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 3, 2026 Read article
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LightGBM-Based Grid Demand Estimation and Prediction for Intelligent Electricity Load Forecasting
Abstract: Correctly predicting electricity demand in emerging energy markets like India is the most effective way to maintain grid stability. This is particularly important. This article offers a comprehensive data- based structure that captures both the broad temporal dynamics and regional diversity. This technique utilizes a large-scale multi-dimensional feature space that includes temporal indicators, autoregressive lag terms, sliding-window rolling statistics, and state-level administrative markers. Our systematic benchmarking approach involves the use …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 3, 2026 Read article
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Teen Pregnancy in the Event of a Pandemic: A short commentary
Abstract: There is a strong correlation between the COVID-19 epidemic and an increase in rates of child marriage and teenage pregnancies around the world. In sub-Saharan Africa, an estimated 608,000 additional girls are at danger of child marriage and 542,000 additional girls are at risk of early pregnancy. A mother's health, as well as the economy and society at large, may suffer if an adolescent decides to get pregnant. Due to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 4, 2023 · pp. 42–45 Read article
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Comparative Analysis of Conventional Formwork with Specialized Emerging Formwork Regarding Project Engineering Factors for High-rise Building
Abstract: Today, because of globalization, there have been a number of improvements in the construction of modern technology worldwide, as a result of the quick and reliable distribution of new and emerging technologies through societies worldwide and the cross-border information sharing. Shaping which helps to mount the concrete in the desired shape It is a critical component of the construction to support the loads placed on it, as well as supporting …
Published in Recent Trends in Civil Engineering & Technology · Vol. 11, Issue 1, 2021 · pp. 65–72 Read article
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Foliar Application of Zinc Nanoparticles Improves Photosynthetic Performance in Wheat Plants
Abstract: The present study investigated the impact of foliar spray of zinc oxide nanoparticles on physiological and biochemical reactions in wheat (Triticum aestivum L.) Foliar spray with zinc oxide nanoparticles at 10 mg/l positively increased pigment content and biomass in comparison to control while a significant reduction in chlorophyll content and biomass accumulation was observed at higher concentration of 1000 mg/l. A study of Chlorophyll a fluorescence parameters at 10 mg/l …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 11, Issue 2, 2021 · pp. 12–23 Read article
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An Approach on Optimization of Thermo Physical Properties of Teak Wood Dust Filled Polymeric Composites
Abstract: The aim of the present work was to prepare the specimens with the help of hand-lay-up technique to measure the thermal properties of TWDPC. The density & voids of TWDPC were measured to determine its physical property & significantly affected some of its mechanical properties. Taguchi experimental method was applied to optimize its thermal properties. The optimal factor combinations were determined with the help of ANOM & the analysis of …
Published in Journal of Polymer & Composites · Vol. 9, Issue 4, 2021 · pp. 67–80 Read article
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Cubic B-splines for Isogeometric Analysis of Laminated Composite Plates Subjected to Hygroscopic Loading Using Classical Laminated Plate Theory
Abstract: Composite laminates are inevitably used in several engineering structures due to their high strength and stiffness to weight ratio. The laminates are subjected to change in moisture content and the flexural behavior leads to change in the strength. Presence of moisutre may induce residual stresses and strains. Isogeometric analysis is a well-proven method to perform analysis of laminated composite plates. The main focus of this study is to apply isogeometric …
Published in Journal of Polymer & Composites · Vol. 9, Issue 4, 2021 · pp. 19–32 Read article