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675 articles for “Novel”
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Early Alzheimer’s Disease Prediction Using Vision Transformers and Attention-Guided MRI Analysis
Abstract: Alzheimer’s Disease (AD) continues to be a major global health concern, with early detection being crucial for effective intervention. While conventional machine learning and convolutional neural network (CNN) approaches have made notable progress in automated AD diagnosis using MRI data, they often struggle with capturing long-range dependencies and maintaining spatial contextual awareness. In this research, we propose a novel framework using Vision Transformers (ViTs) for early Alzheimer’s prediction from 3D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 30–40 Read article
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Graphene–Perovskite Hybrid Opto-Electronic Modulators for Ultra-Low Power Optical Communication
Abstract: This paper proposes a novel self-adaptive neuromorphic opto-electronic transceiver architecture designed to enhance the intelligence, adaptability, and efficiency of next-generation optical communication networks. The proposed system integrates neuromorphic computing principles with photonic signal processing to enable real-time learning, dynamic resource allocation, and autonomous compensation of channel impairments such as dispersion, nonlinearities, and noise. Unlike conventional transceivers, the developed model employs spiking neural networks embedded within opto-electronic circuits to mimic biological …
Published in Trends in Opto-electro & Optical Communication · Vol. 16, Issue 1, 2026 · pp. 41–52 Read article
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Bioenhancer to Boost Herbal Drug Efficacy
Abstract: Bioenhancers are natural substances that significantly improve the absorption, bioavailability, and therapeutic efficacy of drugs when co-administered, without showing notable pharmacological activity of their own. In herbal medicine, the concept of bioenhancement has received growing attention as many phytoconstituents exhibit low oral bioavailability due to poor solubility, limited permeability, and extensive first-pass metabolism. The traditional Ayurvedic system first introduced this concept through the discovery of Piperine, the active alkaloid from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Polymer-Coated Composite Granules of Clarithromycin: Design, Characterization, and Functional Evaluation for Taste Masking and Antibacterial Performance
Abstract: Background: Masking the unpleasant taste of clarithromycin is essential to improve patient adherence, especially among pediatric and elderly groups. However, enhancing palatability while maintaining its antibacterial effectiveness remains a significant formulation challenge. This study focused on developing polymer-coated clarithromycin granules (B1–B10) using novel non-sugar-based polymers and assessing their antibacterial activity against Staphylococcus aureus Methods: Clarithromycin granules were produced using a fluidized bed coating technique with non-saccharide polymers, specifically Eudragit E-100 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1042–1050 Read article
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Fabrication and Characterization of Hybrid Composites Using Natural Fibers Reinforced in HDPE and Optimization of Injection Moulding Process Parameters to Minimize Shrinkage
Abstract: Materials are crucial for advancing human living standards. Over the past 20 years, composite materials have garnered significant attention owing to their unique properties and applications across various sectors. This study outlines the creation and analysis of a novel series of natural fiber-based composites, which incorporate jute, sisal, and hemp as reinforcements, with high-density polyethylene (HDPE) serving as the matrix, and produced through injection moulding. This study examines the effects …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 556–585 Read article
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Uncontrolled Cell Growth and Human Health: A Comprehensive Exploration of Cancer
Abstract: Cancer is a diverse category of diseases defined by the uncontrolled proliferation and spread of aberrant cells. It remains the major cause of morbidity and mortality worldwide. This article presents an overview of the various forms of cancer, such as carcinomas, sarcomas, lymphomas, and leukaemia, emphasising their distinct causes, symptoms, and risks. Early detection and diagnosis are emphasized as key to enhancing treatment outcomes. The article further provides an in-depth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 1–23 Read article
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Corrugated Tube Shell-and-Tube Heat Exchanger Using Epoxy-Based Polymer Composite Coatings for Lightweight and Efficient Thermal Systems
Abstract: Corrugated tube geometries are widely recognized for their ability to enhance heat transfer through boundary layer disruption and secondary flow generation. In this study, a combined experimental and computational investigation is carried out to evaluate the thermo-hydraulic performance of a shell-and-tube heat exchanger incorporating corrugated stainless steel tubes integrated with an epoxy-based polymer composite coating and housed within a mild steel shell. Unlike conventional metallic systems, the present work introduces …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 603–617 Read article
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Modern Chemistry & Chemical Technology in Sensor Formation
Abstract: The field of sensor formation stands at the vibrant intersection of modern chemistry and chemical technology, driven by an insatiable demand for precise, rapid, and sensitive detection across myriad applications. This paper explores the foundational and transformative role these disciplines play in engineering next-generation sensing platforms. Modern chemistry, through its atomic-level precision in synthesizing novel responsive materials – ranging from advanced polymers and supramolecular architectures to cutting-edge nanomaterials like graphene, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 1–9 Read article
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Looking into new ideas in green chemistry
Abstract: Green chemistry has become a revolutionary way to change chemical processes such that they have less of an effect on the environment while still being efficient and cost-effective. This article looks at new developments in green chemistry that go beyond small changes and offer completely new ways to build chemicals that are good for the environment. There is a lot of focus on innovative catalytic systems, sustainable feedstocks, reaction pathways …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 10–18 Read article
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Multi-Layered AI-Driven Paradigm Shift in IoT Ecosystem Security
Abstract: As the Internet of Things (IoT) continues to weave itself into the fabric of modern life – from smart homes and industrial automation to healthcare and urban infrastructure – the associated security vulnerabilities have become increasingly apparent. Traditional security mechanisms, often built on static rules and perimeter-based defenses, struggle to keep pace with the scale, heterogeneity, and dynamic nature of IoT ecosystems. In response, artificial intelligence (AI) has emerged as …
Published in Journal of Communication Engineering & Systems · Vol. 16, Issue 1, 2026 · pp. 13–21 Read article
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Quasar: Quantum-Accelerated Sustainable Anomaly Recognition in Climate Systems
Abstract: Accurate detection of climate anomalies is vital for disaster alleviation and policy making in a sustainable manner, but customary detection methods face the challenges of computational inefficiency and physical inconsistency. In this study, we propose a novel approach called Quantum-Optimized Fuzzy Physics-Informed Neural Networks (QFuzzy-PINNs), which integrates quantum computing, fuzzy logic, and physics-informed deep learning. As a first step, we employ quantum annealing for conventional optimization to adjust multiple Gaussian …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 18–27 Read article
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Multiphysics Optimization of Polymer–Metal Hybrid Electrode Geometry in Electrostatic Precipitators for Enhanced Particle Collection Efficiency
Abstract: Electrostatic precipitators (ESPs) remain one of the most effective technologies for controlling fine particulate emissions in industrial exhaust systems. However, their performance is strongly influenced by electrode geometry and material characteristics, which govern electric field distribution, corona stability, and particle migration behaviour. In this study, a comprehensive numerical investigation is carried out to optimize electrode geometry using a multiphysics modelling framework, while introducing a novel polymer–metal hybrid design to enhance …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 701–716 Read article
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Comparative Analysis and Future Research Directions in AI in Healthcare: Medical Imaging and Diagnostics
Abstract: Artificial intelligence (AI) is reshaping healthcare, particularly in the areas of medical imaging and diagnostic practice. By using advanced techniques like machine learning and deep learning, AI systems help improve the accuracy, speed, and effectiveness of identifying diseases and analyzing medical images. This paper provides a comprehensive overview of the application of artificial intelligence in medical imaging and highlights its growing importance in clinical diagnostics. It discusses how AI-based systems …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 8–13 Read article
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Machine Learning Optimization for VARTM Carbon Polymer Laminates
Abstract: Vacuum-assisted resin transfer moulding (VARTM) is a key low-cost, out-of-autoclave process for manufacturing large-scale carbon-fibre reinforced polymer (CFRP) laminates crucial to aerospace wings, wind-turbine blades, marine hulls, and automotive structures. Unpredictable resin flow often leads to voids, dry spots, and race-tracking defects, resulting in 27.9% scrap rates and lengthy, costly trial-and-error design cycles. Although surrogate models provide rapid impregnation predictions for simple flat-plate geometries, vision-based monitoring is limited to idealized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 229–245 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Experimental and CFD Investigation of an Epoxy-Based Thermally Conductive Polymer Composite U-Tube Shell-and-Tube Heat Exchanger: A Lightweight Alternative to Conventional Metal Systems
Abstract: Shell-and-tube heat exchangers continue to play a critical role in industrial thermal systems; however, their conventional design based on fully metallic materials often leads to challenges related to weight, corrosion, and cost. In recent years, thermally conductive polymer composites have emerged as promising alternatives, offering improved corrosion resistance and design flexibility. In this study, the thermo-hydraulic performance of a U-tube shell-and-tube heat exchanger is investigated by partially replacing conventional metallic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 685–700 Read article
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Comparative Assessment of Methylparaben concentration in Cosmetic product, analyzed using Enzyme Biosensor and ultra-high-pressure liquid chromatography (UPLC): An approach towards detection of the environmental toxicant with higher accuracy and sensitivity.
Abstract: Methylparaben (MP) is one of the most widely used preservatives and is associated with a catalog of recently identified health hazards. Existing studies have also highlighted these compounds as environmental contaminants and toxicants that affect water quality and the associated microbial diversity of the habitat. The conventional methods for parabens detection is performed using chromatographic techniques, which assist in quantitative analysis of the group of compounds. However, the biggest challenge …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
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Polymer Composite-Assisted Crystal Engineering for Drug Synthesis and Property Control through Solid Solutions and Co-Crystals
Abstract: The long-standing problem of low aqueous solubility, which affects about 90% of all new drug molecules under development, requires an immediate need for alternative approaches apart from the usual practice of crystallization. Polymer-composite-assisted crystal engineering is a novel technique for overcoming the aforementioned problem. This involves the addition of accepted pharmaceutical polymers, such as HPMC, PVP, PEG, and Eudragit copolymers in a single process, which can promote nucleation, stabilize the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 172–189 Read article