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1982 articles for “optimization” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Solar Tracking System and Battery Management
Abstract: This project focuses on optimizing renewable energy systems by combining a dual-axis solar tracking mechanism with a smart Battery Management System (BMS) to improve solar energy harvesting and storage. The system uses an Arduino Uno microcontroller and Light Dependent Resistors (LDRs) to track the sun's position, enabling the solar panel to adjust its orientation in real-time for optimal sunlight exposure throughout the day. At the same time, the integrated IoT-based …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 17, Issue 2, 2026 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Designing and Analysis of Different Types of Fins in Air Cooled Engine
Abstract: This paper is dedicated to the study of various shapes of extended surfaces, commonly known as fins, which are used on cylinder heads of internal combustion engines. Extended surfaces are used to improve heat dissipation from the object by increasing its effective surface area. Efficient heat dissipation is very important since proper cooling of an engine cylinder head helps to maintain optimal working temperatures, improves engine performance, increases service life, …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 33–79 Read article
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Adhesively Bonded Patch Repair in Polymer Composites: Effects of Reinforcement Configuration and Post-Cure Temperature
Abstract: Adhesive patch repair technique has been identified as an effective and economical approach to repair damaged polymer composite structures that are used in aerospace, automotive, marine, wind energy, and many other high-performance engineering applications. Adhesive bonding offers superior stress distribution, reduced stress concentration, less structural weight and fatigue resistance, and thus increases the lifetime of the repair of composite structures when compared to the traditional mechanical attachment approaches. Performance and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 991–1001 Read article
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Passive Augmentation Studies in a Double Pipe Heat Exchanger with Ellipsoidal Dimples
Abstract: In this work, the numerical studies of heat transfer augmentation of a counter-current double pipe heat exchanger with ellipsoidal dimples (inward-facing, raised dimples) on the inner tube was performed using SOLIDWORKS software. The effect of dimple depth, dimple pitch and number of dimples/angles between two dimples on heat transfer was investigated at a constant volumetric flow rate of 4 LPM for hot (water) and cold (water) fluids. The effect of …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 2, 2026 Read article
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Zeolite-Y Encapsulated Copper (II) and Cobalt (II) Species as Hybrid Nano-catalysts: Structural and Catalytic Aspects
Abstract: Special properties inherent to zeolites in facilitating the construction of novel upramolecular assemblies by encapsulation of guest molecules (metal complexes) into their large cages can be utilized to use these assembled materials as novel catalysts. These modified solids have the advantages of both behaving as the homogeneous and the heterogeneous catalytic system. In the present work, copper (II) and cobalt (II) complexes of 2-amino ethanoic acid (2-AEA) encapsulated in the …
Published in Journal of Catalyst & Catalysis Read article
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Electroplating and Corrosion Properties of Binary and Ternary Zinc Alloys with Nickel, Cobalt and Iron
Abstract: The anti-corrosive three binary (Zn-Ni, Zn-Co, Zn-Fe) and two ternary (Zn-Ni-Co, Zn-Co-Fe) alloy coating films on mild steel from acid chloride bath using sulphanilic acid and gelatin as additives for the electroplating technique. The normal Hull cell method was used to optimize the bath compositions, temperature and pH of the bath solutions for coating performance against corrosion. The cause of current density (CD) on metal weight percentage (M = Ni, …
Published in Journal of Thin Films, Coating Science Technology & Application Read article
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Design and Simulation of LNA in 90 nm CMOS Technology for Radio Receiver using the Cadence Simulation Tool
Abstract: Due to its successful operation in the 2.4 GHz frequency region, often known as the ISM (Industrial, Scientific, and Medical) band, RFICs play a vital role in communication systems. The major parts being used transceivers for frequency translation and amplification are LNA and Mixers. Different types of mixers and LNAs are employed, and different strategies are used to optimize them. In this paper an approach for design and simulation of …
Published in International Journal of Digital Communication and Analog Signals Read article
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Development of Game Theory Strategy for Estimating Mobility Variety in Approaching Wireless Networks
Abstract: Game theory designed with a set of structured tools with an evaluation tool for the tedious interaction among logical players. This theory approaches for analyzing of communication networks, which functions with autonomous structured networks and the designed network devices can take rational decisions according to network congestion. The proposed structure consists of mixture frame for channel allocation for random probability for accessing channel. The main objective of this work is …
Published in Recent Trends in Electronics Communication Systems Read article
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Experimental Analysis of Nano-carbon Doped Alumina for Industrial Applications
Abstract: The use of nano-carbon metal matrix composites can provide a solution to the enduring issue of optimal material selection and optimization for getting metal-insulator transition (MIT) behavior at a particular frequency at ambient temperature. Other substances, like two-dimensional (2D) transition metal dichalcogenides (TMD), vanadium oxide (VO2), and germanium telluride (Ge-Te), have difficult challenges in achieving effectively the MIT property at a given frequency and temperature. It is also difficult to …
Published in Journal of Polymer & Composites Read article
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Parametric Study of Fused Deposition Modelling Process During Fabrication of Acrylonitrile Butadiene Styrene (ABS) Based Injection Molding Die
Abstract: The purpose of this study is to dictate an optimum process parameter during the fabrication of additively manufactured acrylonitrile butadiene styrene (ABS) based injection mold using fused deposition modelling methodology based additive manufacturing process and to assess the quality of the infection mold by analyzing the surface roughness of the injection mold, and the time taken in the manufacturing of the mold. The ABS PRO+ filament is used in manufacturing …
Published in Journal of Polymer & Composites · Vol. 10, Issue 1, 2022 Read article
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The Past, Present, and Future of Power Conversion Technologies for Computer, Networking, and Telecom Power Systems
Abstract: The power systems of modern computers, networking, and telecom equipment face formidable challenges due to the ongoing increase in power-density and efficiency requirements. Significant technological breakthroughs in system designs, devices and materials, topology optimization, and packaging/thermal design will be necessary to meet these objectives. To address these challenges, ongoing research and development efforts are being conducted in academia, industry, and government institutions. These efforts aim to revolutionize power system designs, …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 16–31 Read article
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Minimum Energy Criteria for Machining to Determine Energy-Productivity Relationship
Abstract: In this research segment, cutting rates were changed while depth of cut and feed rate remained fixed. The results of cutting using a standard uncoated carbide insert were compared. Cutting speeds were maintained at a constant. After determining the optimal cutting condition for the equipment and material. To determine optimal tool life and cutting speed, turning operations were performed. In industrial cutting operations, flank wear reduces tool life. For single-point, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 81–94 Read article
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TiO2 Refined Flux Provides Significant Impact on Saw Bead Shape, Particle Size, and Hardness
Abstract: This experiment is very interested in how adding titanium dioxide powder to submerged arc welding on low alloy steel plates affects the bead geometry, grain size, and hardness. The commercial fluxes were combined with powdered titanium dioxide at varying concentrations (2.5%, 5%, 7.5%, 10%, and 12.5%). No changes were made to the welding process parameters despite the variety of welding situations. It has been shown that the inclusion of titanium …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 70–80 Read article
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Recognition of Engine Parameters for Mahua Biodiesel by Analyzing the Performance Using OFAT Approach
Abstract: The review work deals with the prediction of significant engine input parameters by the use of one factor at a time approach. The technique is a trial of experiments by varying only one engine input parameter and others remain at constant values. The various engine input parameters are found from the literature review. In the current work, six engine input parameters are predicted from the past research. These are blending …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 1, 2023 · pp. 1–10 Read article
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Design and Development of Ankle Foot Orthosis for Foot Amputated Person by Using Carbon Fibre
Abstract: Ankle and foot orthotics play a pivotal role in the rehabilitation of individuals who have suffered a stroke, aiding in the restoration of their gait and overall mobility. However, optimizing the effectiveness of these orthoses requires a personalized approach that takes into account each patient's unique biomechanical characteristics. This study delves into the innovative use of carbon fiber combined with cost-effective 3-D printing technology to craft custom foot plate orthoses …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 115–121 Read article
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Solar Powered Irrigation System Design with Venturimeter for Utilizing Natural Resources
Abstract: This research focuses on enhancing crop productivity in agriculture by ensuring high quality and quantity of crops. Crops needs to be given adequate nutrients in an efficient and timely fashion as a way to accomplish this.. Thus, liquid-based fertilizers are selected for this purpose. However, farmers often face challenges in supplying fertilizers with the required quantity and precision. To address this issue, we propose a solution that leverages solar energy …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
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QCA-based Implementation of Budget-friendly and Energy-Efficient Exclusive-OR/Exclusive-NOR Gates
Abstract: Quantum-dot cellular automata (QCA) is a novel nanoscale computational approach that proposes reduced dimensions, lower power consumption, increased speed, and deliberate design as a solution to the scaling challenge associated with CMOS technique. QCA is a nascent nanotechnology that utilizes the Coulomb repulsion principle. Quantum computing has emerged as a highly effective paradigm for the creation of energy-efficient hardware at the nanoscale. This article presents implementation of a very efficient …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 2, 2023 · pp. 1–6 Read article
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Investigations on Anthocyanin and Its Regulatory Role
Abstract: Anthocyanin is the most widely studied and abundant group of natural pigments. It has been gaining increased attention for its potential health benefits. This vibrant, water-soluble pigment is found in fruits, vegetables, and flowers, and is responsible for the colors of many of the foods we eat. Anthocyanins are not only responsible for the aesthetic appeal of these foods, but they are also believed to have powerful antioxidant, anti-inflammatory, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 32–37 Read article