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619 articles for “Subtractive Synthesis”
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Leucoanthocyanidin Reductase (LAR) Gene Analysisin Reductase
Abstract: Leucoanthocyanidin reductase (LAR) catalyzes the synthesis of catechin that is first step in PA biosynthesis. LAR involved in production of the flavan-3-ol. LAR gene is involved in proanthocyanidine production in several plants. Proanthocyanidins are plant secondary metabolites and occur in a wide range of plants and play an important role in defense against herbivores. The analysis of 50 proteins by global alignment of EF148325 with other ortholog sequences which have …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 2, 2013 · pp. 15–27 Read article
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High Doses Biotin beyond Its Nutraceutical Prescription: Update Indications for Neurological Diseases
Abstract: Biotin or vitamin H is ubiquitous B-complex vitamin that plays as a co-factor in different metabolic process in the body. The usual recommended daily requirement is 30µg. Recent studies found biotin in high doses involved in the synthesis of myelin in patients with multiple sclerosis. The Med Day Pharmaceuticals launched an oral formulation of biotin high dose (Cerenday 100 mg capsule) and recommended for multiple sclerosis. Previous studies demonstrated the …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 2, 2017 · pp. 13–20 Read article
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Evaluation of the Effect of Zinc Supplementation on Glycemic Control and Lipid Profile in Normoglycemic and Streptozotocin-induced Type-2 Diabetic Rats
Abstract: Diabetes mellitus is a chronic, progressive disease, which is accompanied by multiple complications. Hyperglycemia and dyslipidemia are common complications of diabetes mellitus. The current approaches for treatment of diabetes are mostly dependent on insulin and other oral standard drugs, which have their own put falls. Thus, micronutrients supplementation is gaining momentum as the quest for management of diabetes continues. Certain micronutrients increase insulin synthesis secretion and insulin sensitivity thereby improve …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 41–51 Read article
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Benzimidic Acid Derivatives as Potential Anti-Escherichia coli Agent for Preventing Nosocomial Infections
Abstract: Based on the global fame of benzimidic acid/benzoic acid derivatives in exhibiting antimicrobial activities against a variety of pathogens (particularly nosocomial infections), two novel compounds (S1 and S2) of benzimidic acid scaffold were rationally designed from a hydrazine derivative and fabricated using the conventional synthesis technique. Through sophisticated instruments, the molecules were comprehensively characterized and investigated for antibacterial activity against pathogenic Escherichia coli strain (MTCC 2961). The novel benzimidic compound …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 11–15 Read article
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A Review Drug and Biochemical Pharmacology Discovery
Abstract: The development of new therapeutic approaches and our understanding of disease mechanisms have both benefited ground-breaking medications as they are advanced and show the value of contemporary technologies, methodologies, and genetics in drug discovery. The synthesis, design, and application of these molecules have become a focal point in drug discovery efforts. The present research paper provided a comprehensive study of the recent developments in the field of biochemical pharmacology and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 27–31 Read article
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Production and Characterization of Cardanol Based Schiff Complexes and their Biological Significance
Abstract: Synthesis and analysis of cardanol consisted Schiff base ligand along with its complexes such as Cu, Co and Ni are considered as a novel tetradentate cardanol contained Schiff base ligand molecules for various biological effects. It is prepared by the condensation reaction of 2-aminophenol and di-α formylmethoxybis (3-pentadecenyl phenyl) methane which is termed as DFMPM in the molar ratio of 2:1. The characterization of the experimental compounds is done with …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 19–24 Read article
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Biotechnological Applications for Microalgal Enzymes
Abstract: Enzymes are essential components of biological reactions and serve significant roles in the scalability and optimization of many industrial processes. Because of the rising economic demand for newer and more efficient enzymes to help further optimize these processes, many researchers are now focusing their efforts on more renewable and environmentally friendly sources to generate these enzymes. Microalgae are especially promising in this area since they can be cultivated in photobioreactors, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 1, 2022 · pp. 24–27 Read article
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Glutathione: Postoperative Study in Breast Carcinoma
Abstract: Breast cancer represents a significant problem in the world. Glutathione a tripeptide is found in all mammalian tissues. Thus any change in its synthesis or utilization can profoundly influence the redox status of cells. In this study blood sample was collected from 60 FNAC confirmed breast cancer patients (preoperative and postoperative three months) and 30 normal healthy controls for the estimation of glutathione. There was significant increase in glutathione in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 3–6 Read article
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Nitric Oxide Synthase (NOS) in Breast Carcinoma
Abstract: Breast cancer is the most alarming problem of the current time. Nitric oxide, a free radical gas is synthesized by isoenzymes called nitric oxide synthase. Nitric oxide synthase consists of three isoforms; Nitric oxide produced is cytotoxic which is known to inhibit the DNA synthesis causing its damage. Keeping this in mind, nitric oxide synthase was determined in breast cancer and normal breast tissue. For this tissue from 60 breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 1, 2018 · pp. 23–28 Read article
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Inhibition of MDA-MB-231 Breast Cancer Cell Proliferation by Simple Diphenyl Chalcone and Its Chlorinated Derivatives
Abstract: The pharmacological activities of chalcones and their derivatives are well documented. Chalcones are an important class of natural products that occur in edible plants such as spices, tea, fruits and other vegetables. In vitro studies have shown that chalcones inhibit proliferation of breast cancer cells by inducing apoptosis and blocking cell cycle progression. Substituent effects, namely, adding electron-withdrawing substituents to the chalcone structural motif, and the extents to which those …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 2, 2012 · pp. 7–12 Read article
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Ameliorating Effect of Vitamin C on Acid Orange 7 Induced Oxidative Stress in the Gill of the Fish, Anabas testudineus (Bloch, 1792)
Abstract: Acid orange 7, an azo dye, was exposed to Anabas testudineus at a sublethal concentration (0.27 g/l) for 24, 72 and 96 h in order to evaluate the antioxidant status in the gill tissue. In addition, vitamin C at 0.55 g/l was exposed for 7 days after the dye exposure. Acid orange 7 decreased the body weight of fish, whereas mucous deposition increased significantly as the first line of defensive …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 15–27 Read article
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Production, Characterization and Toxicological Evaluation of Eco-Friendly Flavolipid Biosurfactant
Abstract: At present majority of surfactants are chemically synthesized. Nevertheless, in recent years, much attention has been directed towards biosurfactants due to their broad range of functional properties, there are cheaper as they can be produced from alternative sources. They have applications in the fields, such as: oil recovery process, as an additive in food processing industry, pharmaceuticals preparations, energy saving technologies etc. As they are being microbial derivatives, it is …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 16–21 Read article
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Role of Endogenous and Exogenous Glutathione in the Detoxification of Free Radicals
Abstract: The aging process and disease progression are the result of cellular damage by free radicals. Our first lines of defense against free radical damage are the antioxidants. They are critical for keeping optimal health and wellbeing. The need for antioxidants becomes more critical with increased exposure to free radicals. Pollution, drugs, cigarette smoke, illness, stress, and even exercise can increase free radical exposure. The accumulation of free radicals produced from …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 1–14 Read article
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From Prototype to Production: A Review of Industrial Applications for 3D Printing in Aerospace, Automotive, Biomedical, and Electronics
Abstract: Three-dimensional (3D) or Additive Manufacturing has made remarkable progress from rapid prototyping to large-scale production. Several industries like aerospace, automotive, biomedical, and electronics utilise AM technology for product personalisation, minimising waste material, reducing the cycle time of product design, and designing complex shapes that are difficult to manufacture using traditional techniques like subtractive manufacturing. This paper evaluates the evolution of 3D printing technology from prototyping to industrial production. In addition, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 2, 2026 Read article
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Architectural Evolution of RISC Processors: From Early Research Prototypes to Modern Industrial Implementations
Abstract: This paper surveys the architectural evolution of Reduced Instruction Set Computer (RISC) architectures from early research prototypes to modern industrial processors, tracing four decades of design refinement across academic, embedded, server, mobile, and open- hardware ecosystems. Core ISA principles, pipeline evolution, compiler–hardware co-design, and quantitative performance modeling are analyzed through four representative industrial implementations: MIPS 74K, SPARC T4, ARM Cortex-A72, and SiFive U74 (RISC-V). Each processor is examined in terms …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 2, 2026 · pp. 29–39 Read article
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Polypropylene Fibres in Cementitious Composites: A Critical Review of Polymer Structure, Processing, Interfacial Behaviour and Performance
Abstract: Polypropylene (PP) fibres are widely used as secondary reinforcement in cementitious composites, yet their performance is governed as much by polymer structure and interfacial chemistry as by dosage. This review synthesises 50 primary sources (2003-2025, concentrated post-2015) to examine how PP molecular structure, fibre-manufacturing history, morphology, surface properties and environmental ageing govern fibre-matrix interaction and multiscale composite performance. Isotacticity, molecular weight, crystallinity and drawing ratio are shown to set the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Binary GA for Sidelobe Reduction and Null Steering in 5G Array
Abstract: This paper presents a comprehensive performance evaluation of a Binary Genetic Algorithm (BGA) for optimizing radiation characteristics of an active phased array antenna used in fifth-generation (5G) wireless communication systems. The primary objective is to achieve effective null steering while maintaining the desired main beam direction and simultaneously reducing the side lobe level (SLL). These improvements are essential for minimizing co-channel interference, enhancing spatial selectivity, and improving the Signal-to-Interference-plus-Noise Ratio …
Published in International Journal of Radio Frequency Innovations · Vol. 4, Issue 2, 2026 Read article
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A Promising Approach Towards Arthritis: Bacopa Monnieri
Abstract: Joint inflammation, pain, and a progressive loss of function are the hallmarks of arthritis, a chronic and crippling condition that frequently results in disability and a lower quality of life. The need for safer options is highlighted by the fact that while current therapy approaches, such as NSAIDs, corticosteroids, and disease-modifying antirheumatic medications, give symptomatic relief, they are usually linked to serious adverse effects. In this regard, the wellknown Ayurvedic …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 76–91 Read article
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The Impact of AI-Driven Decision-Making on Consumer Behavior and Sustainable Consumption Patterns in Modern Management
Abstract: The accelerating integration of Artificial Intelligence (AI) into business management systems has fundamentally transformed the dynamics of consumer decision-making and organizational marketing strategies. This paper investigates the multidimensional impact of AI-driven technologies, including predictive analytics, recommendation engines, chatbots, natural language processing, and machine learning algorithms, on consumer behavior and sustainable consumption patterns within contemporary management frameworks. Drawing upon a comprehensive synthesis of empirical studies, theoretical literature, and bibliometric analyses, the …
Published in Journal of Production Research & Management · Vol. 16, Issue 2, 2026 · pp. 12–19 Read article
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Systematic Hydroponic Review and Cultivation Strategies for Bacopa Monnieri
Abstract: Bacopa monnieri (L.) Wettst. (Brahmi; Plantaginaceae) is a medicinally important herb whose nootropic, antioxidant and anti-inflammatory properties derive largely from a group of triterpenoid saponins known as bacosides. Rising global demand for such compounds has made reliable, high-yield production a research priority and has prompted a search for cultivation systems superior to conventional field cultivation. This review compares field cultivation, in vitro micropropagation, bioreactor culture, hydroponics and elicitation for their …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 2, 2026 · pp. 23–28 Read article