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622 articles for “potential treatments”
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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Iatrogenic Damages of Orthodontic Treatment and Its Management: Overview
Abstract: There are so many patients who seek orthodontic treatment for correction of poor esthetic, abnormal functions and speech. The orthodontic treatment improves the esthetics, but not without potentials risks. Every orthodontist wants that the treatment should be accurate for each and every patient without discomforts, pain and long-term side effects. There are so many risks associated with the orthodontic treatment which may be either iatrogenic or inherent. This paper comprises …
Published in Research and Reviews: A Journal of Dentistry · Vol. 5, Issue 3, 2014 · pp. 10–20 Read article
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Service Life Improvement Analysis of Cryogenically Treated Blanking Punch
Abstract: After traditional heat treatment, Cryogenic treatment is carried out as a secondary process to improve the hardness and wear resistance of tool steels. The researchers have already studied and it is well published the potential use of cryogenic treatment of AISI D2 tool steel under laboratory conditions. However, to ensure the sustainable use of this technology for industrial application, its analysis is essential. Therefore, in this work a small scale …
Published in Trends in Mechanical Engineering & Technology Read article
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Service Life Improvement Analysis of Cryogenically Treated Blanking Punch
Abstract: After traditional heat treatment, Cryogenic treatment is carried out as a secondary process to improve the hardness and wear resistance of tool steels. The researchers have already studied and it is well published the potential use of cryogenic treatment of AISI D2 tool steel under laboratory conditions. However, to ensure the sustainable use of this technology for industrial application, its analysis is essential. Therefore, in this work a small scale …
Published in Trends in Mechanical Engineering & Technology · Vol. 11, Issue 3, 2021 · pp. 10–18 Read article
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Restoring Swallowing Freedom: A Triumph Over Achalasia Cardia Type III- A Case Report
Abstract: This case report explores the rare occurrence of achalasia cardia in a 24-year-old male in India, highlighting the unique challenges in diagnosis and treatment. The atypical demographic and the efficacy of laparoscopic Heller's myotomy with Dor's fundoplication underscore the importance of reporting such cases. The background reveals an unusual presentation of achalasia cardia in a 24-year-old male at Ahmedabad, Gujarat, India, justifying its documentation due to the infrequency of this …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 1–5 Read article
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Ivermectin: Its Therapeutic Efficacy in the Treatment of COVID-19
Abstract: Over past 35 years the most commonly used anti-helminthic drug is ivermectin. It has showed good impact in treating the parasitic infections. The drug provides an evidence of immune modulatory and anti-inflammatory actions in vitro animal model. Ivermectin belongs to the class of ivermectin and most widely used as an anti-parasitic agent. It is also used in the treatment of internal nematode infections like onchocerciasis, filariasis, and strongloidiasis. For the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 1–5 Read article
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Literature Review On Nanotechnology In Dentistry
Abstract: Nanotechnology is a relatively new field in dentistry that utilizes nanomaterials, nanorobots, and nanotechnology for diagnosing, treating, and preventing dental diseases. Nanotechnology has revolutionized various fields of dentistry, offering innovative solutions that enhance patient care, improve treatment outcomes, and contribute to the overall advancement of dental science. This cutting-edge technology has found applications in several areas, including restorative dentistry, dental implants, early cancer diagnosis, dental hypersensitivity, and pain management, among …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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Assay of the Antitrypanosomal Activity of Ziingiber Officinale Extract in Wister Rats
Abstract: This research investigated the antitrypanosomal effects of Zingiber officinale in rats infected with Trypanosoma brucei brucei. Twelve adult rats, 7 weeks old and of both sexes, were randomly divided into six groups (1 through 6), with each group consisting of two rats. All six groups (1–6) were intraperitoneally injected with 0.1 ml of blood containing 10⁶ Trypanosomes/ml. Groups 1–4 received daily intraperitoneal doses of the plant extract at concentrations of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 32–37 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Evaluating the Role of Alternative Medicines – A Critical Review of Therapies and Research
Abstract: Alternative medicine encompasses healthcare practices outside conventional medicine, including acupuncture, homeopathy, naturopathy, herbal medicine, yoga, and more. Despite growing popularity, alternative therapies often lack rigorous proof of effectiveness and long-term safety. This review examines various branches of alternative medicine, their benefits, and challenges. The paper discusses Ayurveda, homeopathy, acupuncture, naturopathy, herbal medicines, mind-body therapies, and manipulative and body-based therapies. It highlights the pros and cons of alternative medicine, including holistic …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 1–15 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 52–58 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Artificial Intelligence in Early Diagnosis and Personalized Treatment of Alzheimer’s Disease
Abstract: Artificial intelligence (AI) has become a disruptive technology in the medical care industry, with potential solutions to early diagnosis and customized treatment of Alzheimer’s disease (AD), a progressive neurodegenerative disease and the most prevalent cause of dementia globally. Conventional diagnostic techniques, such as cognitive, neuroimaging and biomarker techniques, are usually limited in the ability to detect disease at its most susceptible stage when treatment interventions are most effective. The recent …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 15–27 Read article
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Comprehensive Review of Recycled Aggregate Concrete in Construction: Suitability, Properties, and Sustainable Practices
Abstract: Concrete production, integral to construction and demolition processes, generates substantial waste. This waste can be repurposed as recycled aggregates in new concrete production, offering sustainable solutions and addressing resource management and environmental concerns. This literature review explores the utilization of construction and demolition waste as aggregates in recycled aggregate concrete (RAC), with a focus on key areas, including the suitability of RAC, its fresh properties, mix design, mechanical characteristics, and …
Published in Recent Trends in Civil Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–8 Read article
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Comprehensive Review of Recycled Aggregate Concrete in Construction: Suitability, Properties, and Sustainable Practices
Abstract: Concrete production, integral to construction and demolition processes, generates substantial waste. This waste can be repurposed as recycled aggregates in new concrete production, offering sustainable solutions and addressing resource management and environmental concerns. This literature review explores the utilization of construction and demolition waste as aggregates in recycled aggregate concrete (RAC), with a focus on key areas, including the suitability of RAC, its fresh properties, mix design, mechanical characteristics, and …
Published in Recent Trends in Civil Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–8 Read article
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article