STM Journals Peer-reviewed research from Consortium e-Learning Network

Research and Reviews: A Journal of Microbiology and Virology

Ivermectin: Its Therapeutic Efficacy in the Treatment of COVID-19

  1. Sreeja Nyayakar
  2. Vidhya Suresh
  3. Aju K. Saji

Abstract

Over past 35 years the most commonly used anti-helminthic drug is ivermectin. It has showed good impact in treating the parasitic infections. The drug provides an evidence of immune modulatory and anti-inflammatory actions in vitro animal model. Ivermectin belongs to the class of ivermectin and most widely used as an anti-parasitic agent. It is also used in the treatment of internal nematode infections like onchocerciasis, filariasis, and strongloidiasis. For the treatment of scabies and pediculosis, ivermectin is given through oral route. Ivermectin is a broad spectrum drug having high lipid solubility shows effects on parasites, mycobacterium nematodes etc. The severe acute respiratory symptom corona virus 2, a single stranded RNA virus out brake on December 2019 and spread to various other countries. The in vivo animal study shows ivermectin has board range of antiviral action. Ivermectin, a potential candidate in the treatment of variety of virus including COVID-19 as well as single stranded RNA virus.

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