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107 articles for “medication resistance”
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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Enhancing Performance of Hybrid Natural Fiber Reinforced Polymer: Insights into Processing, Characterization and Machining
Abstract: Natural fibre reinforced polymer composites (N-FRP) have gained popularity in recent years as an alternative to regular polymer composites, owing to growing environmental concerns. Natural fibers are becoming increasingly popular due to their outstanding properties such as flexibility, strength, compatibility with living creatures, and impact resistance. A notable application of natural fibers is in the medical industry, with the goal of producing cost-effective, sustainable, and long-lasting products. Combining different fibers …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 139–153 Read article
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Polymer-Based Medical Restraints: Advances in Polymer Chemistry for Enhanced Patient Safety
Abstract: Medical restraints play a crucial role in ensuring patient and staff safety during medical procedures, particularly when dealing with individuals who may be at risk of self-harm or unintentional movement. Traditional restraints, often made from rigid materials or fabric straps, present several challenges, including patient discomfort, pressure injuries, and incompatibility with advanced medical imaging techniques such as MRI and CT scans. Moreover, traditional materials may deteriorate over time, diminishing their …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 153–157 Read article
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Nutritional Management of Polycystic Ovarian Disease: Integrating Unani and Contemporary Approaches
Abstract: In Unani medicine, dietary management, known as Ilaj bil Ghiza, plays a vital role in restoring humoral balance and maintaining a healthy temperament (mizaj). This principle aligns with modern medical understanding, particularly in conditions, like polycystic ovarian syndrome (PCOS), which is often associated with insulin resistance and obesity. Modifying dietary habits has shown promise in improving both metabolic and reproductive functions in PCOS patients. Unani scholars attribute PCOS to a …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 1–6 Read article
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Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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Effect of WEDM Machining Parameter on the MMC: A Review
Abstract: Recent area of manufacturing is highly focus on good accuracy and a complex shapes are mechanized by the advanced machining operation. The wire electrical discharge machining (WEDM) have the ability to produce the complex shapes with having high accuracy. The WEDM is non-contact type machining operation and is used for metal materials as well as Metal Matrix Composites (MMCs), ceramics composites those have many application in vast areas such as …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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AI Adoption in Medical Libraries: A Study on SDMH’s Use of Ovid Discovery AI and Its Impact on Evidence-Based Medicine
Abstract: The role of Artificial Intelligence (AI) in transforming medical libraries is increasingly significant as these libraries evolve to become intelligent, responsive hubs for knowledge dissemination. This paper explores the adoption of AI tools at Santokba Durlabhji Memorial Hospital (SDMH) Medical Library, focusing on the integration of Ovid Discovery AI, a cutting-edge tool designed to enhance literature search accuracy, summarize content, and provide context-aware recommendations. Using a mixed-methods approach, the study …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 2, 2026 · pp. 1–9 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Molecular Docking of Saraca asoca (Ashoka) Phytocompounds for Ovarian Cancer Therapy
Abstract: Objective: One of the top five cancers that causes death in women is ovarian cancer, with increases awareness till date the rate of survival is unpredictable. Even though there are advance treatments introduced, chemotherapy is most suggested to the ovarian cancer patients but the rate of relapses increased and the tumors get resistant towards the drugs. This present study is to evaluate the interaction of phytocompounds from Saraca asoca an …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 27–35 Read article
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Application of Some Essential Bacterial Probiotics in Aquaculture: A Review
Abstract: Aquaculture plays an essential role in maintaining food security and sustainable lives for the world’s ever-growing population. Due to the expansion, intensification, and variety of aquaculture methods, aquatic animals confront significant challenges, including disease outbreaks, decreasing output, and risks to the sustainability of the sector. Poor soil conditions in aquaculture cause higher mortality, a higher prevalence of diseases, and lower yields of aquatic organisms. Overfeeding, dead animals, and feces from …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 22–30 Read article
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Short Review: The Expanding Role of Shape Memory Alloys in Technology and Medicine
Abstract: Shape Memory Alloys (SMAs) are a unique class of smart materials that can recover their original shape when exposed to specific stimuli, such as temperature or magnetic fields. This exceptional property, attributed to the martensitic phase transformation, has garnered significant interest in various industries. SMAs exhibit remarkable characteristics such as pseudoelasticity, high corrosion resistance, excellent biocompatibility, and superior fatigue strength, making them ideal for applications in biomedical, aerospace, automotive, and …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 35–44 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Gene Editing and Its Implications for Animal Health
Abstract: Gene editing technologies, particularly CRISPR/Cas9, have revolutionized the field of veterinary medicine, offering unprecedented opportunities for precise genetic manipulation in animals. This review explores the potential applications of gene editing in enhancing animal health, focusing on disease resistance, breeding programs, and the associated ethical considerations. Beginning with an overview of gene editing techniques, we discuss the utility of CRISPR/Cas9 in targeted genetic modifications and compare its advantages and limitations relative …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 1, 2024 · pp. 13–17 Read article
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Paediatric Epilepsy: Current Advances in Diagnosis and Management
Abstract: Paediatric epilepsy is one of the most common chronic neurological disorders of childhood, characterised by recurrent unprovoked seizures resulting from abnormal neuronal activity. Accurate diagnosis is essential and is based on a detailed clinical history, seizure semiology, neurological examination, and electroencephalography (EEG), with neuroimaging such as magnetic resonance imaging (MRI) used to identify structural abnormalities. Classification according to seizure type and underlying aetiology genetic, structural, metabolic, immune, infectious, or unknown—guides …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 53–68 Read article
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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The Role of Polymer Chemistry in Developing a Novel Polymer-Based Retromolar Endotracheal Tube
Abstract: This study presents the development and characterization of a novel polymer-based modified endotracheal tube designed for retromolar intubation. The tube is manufactured using medical-grade polyvinyl chloride (PVC) with reinforced polymeric structures to enhance flexibility while maintaining lumen integrity. The incorporation of a preformed lateral curvature mitigates airway resistance and airflow reduction caused by manual bending, ensuring an optimal balance between rigidity and adaptability. Additionally, the integration of polymer-based ligature wires …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 14–20 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Phytochemical profiling and LC/MS analysis of Selaginella bryopteris (L.) Baker
Abstract: Selaginella bryopteris (L.) Baker, an endemic pteridophyte is found restricted to the Indian subcontinent mostly because of its environmental requirements of cool temperatures and optimum water availability. It is a drought-resistant species and shows curling in limited water supply reviving when water conditions are restored. This property makes this species a suitable plant for exploration of medicinal properties, although its restricted occurrence has limited this evaluation. The current study explores …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 1, 2025 · pp. 46–51 Read article