Search
71 articles for “infectious”
-
Cartridge-Based Nucleic Acid Amplification for Rapid Tuberculosis Diagnosis
Abstract: In terms of public health, tuberculosis continues to have a significant impact on people's lives. The process of determining the underlying cause of a sickness or condition in a patient is known as clinical diagnosis. It entails the use of numerous diagnostic methods, including physical examinations, laboratory testing, and imaging procedures for medical purposes. Smear microscopy, which are frequently utilized, have poor sensitivity and lengthy turnaround times, respectively. An innovative, …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 43–48 Read article
-
Viral Chronicles: The Ever-Evolving Saga of COVID-19
Abstract: Coronaviruses, belonging to the family of RNA viruses, have recently captured global attention owing to their remarkable ability to infect a diverse array of species, ranging from animals to humans. These viral agents, recognized by their characteristic crown-like morphology when observed through electron microscopy, have a historical association with zoonotic diseases. Previous examples include Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The term "Corona" …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 16–25 Read article
-
Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
-
Effectiveness of Structured Teaching on Immunization Knowledge and Attitude Among Mothers of Children Under-5 years of Age at Bal Mahila Chikitsalaya, Lucknow
Abstract: This section offers a thorough overview of the study's background, explaining the significance of vaccination, the variables affecting vaccination coverage, the role mothers play in the decision-making process regarding vaccinations, and the necessity of focused interventions to improve immunization uptake among children under five. As a fundamental component of preventive healthcare, immunization shields both individuals and communities from a variety of infectious diseases. In order to comprehensively assess changes in …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 5–22 Read article
-
Face Mask Detection on Real Time Images and Videos using Deep Learning
Abstract: A big change has occurred in our day-to-day lives as a result of COVID-19. One of these changes is the widespread adoption of face masks as a preventative measure against the transmission of the virus. Because of this, face mask detection has developed into an indispensable technique in a variety of contexts, ranging from public areas to industrial settings. Artificial intelligence (AI) and machine learning algorithms are utilized in the …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 22–30 Read article
-
Climate Change and Economic Vulnerability in Pakistan: An Analysis of Future Risks
Abstract: This paper discussed effects of climate change on economic vulnerability in Pakistan. The findings show that the nation's economy is negatively impacted by climate change. Poverty, unemployment, crime, forest fire, diseases, migration, internal displacement, urban slum, flood etc. will be increase in future due to climate change. Biodiversity and economic balance will be disturbed. Food production, electricity supply, basic infrastructure will be badly affected. Development activities in water resources, as …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 39–46 Read article
-
Comparison Study of Non-Alcoholic Sanitizer and Alcohol Based Sanitizer
Abstract: Hand sanitizer is the best choice to maintain the hand hygiene and stopping the spread of infectious diseases. The active ingredient in traditional hand sanitizers is usually alcohol, but worries about flammability, skin irritation, and possible abuse have prompted the creation and growing popularity of alcohol-free substitutes. The purpose of this review is to objectively assess the safety, effectiveness, and usefulness of alcohol-free hand sanitizers. To successfully eradicate germs, alcohol-free …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
-
Social Determinant in Health : Epidemiological study of communicable diseases, Demography and Mortality rate.
Abstract: Introduction: Social Determinants of Health (SDH) significantly influence the spread and prevalence of communicable diseases. Factors such as poverty, income inequality, healthcare access, education, employment, location, and social connections shape disease transmission within populations. Additional factors like age, gender, migration, and urbanization further explain the relationship between SDH and public health. Mortality rates, including life expectancy, infant mortality, and access to clean water and sanitation, are deeply affected by these …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 41–56 Read article
-
Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
-
Perception of Islamic Scholars towards Polio Vaccination in Northern Nigeria
Abstract: Poliomyelitis, commonly known as polio, is a highly infectious disease that can lead to permanent paralysis and, in severe cases, death. Despite global efforts to eradicate polio through vaccination, Nigeria, particularly its Northern region, has faced significant challenges in reaching full immunization coverage. Resistance to polio vaccination is often rooted in cultural and religious concerns, with Islamic scholars playing a significant role in shaping public perception and acceptance of health …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 28–42 Read article
-
A Study to Evaluate the Knowledge of Menstrual Cups Among Engineering Students at Selected Colleges in Kuppam, Andhra Pradesh
Abstract: Background and Aims:Menstrual cups are an eco-friendly and cost-effective alternative to sanitary pads, yet they have not gained widespread popularity among Indian women. This study aims to evaluate the knowledge of menstrual cups among engineering students at selected colleges in Kuppam, Andhra Pradesh, to better understand awareness and acceptance of this alternative menstrual product. Materials and Methods: A cross-sectional descriptive research design was employed. A total of 143 engineering students …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 45–52 Read article
-
Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
-
Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
-
Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
-
A Study to Evaluate Nurse Led Intervention Regarding Home Care Management Among Tuberculosis Patients Attending Chest and TB OPD at PGIMS Rohtak
Abstract: Introduction: Tuberculosis is an infectious bacterial pathogen caused by the bacillus called Mycobacteriumtuberculosis, an acid-fast rode shaped bacillus 0.8–5 μm in length and 0.2–0.6 μm in thickness. Tuberculosis (TB) primarily impacts the lungs (pulmonary TB), but it can also affect other parts of the body (extra-pulmonary TB). It spreads through the air and causes damage to the lungs and various other organs. TB is a significant public health issue in …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 31–36 Read article
-
Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
-
Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
-
In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
-
Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
-
Nanoformulation Strategies: Emerging Innovations in Drug Delivery Systems
Abstract: Nanotechnology is significantly advancing the pharmaceutical industry by introducing nanosystems that improve drug delivery, therapeutic efficacy, and patient outcomes. Various nanosystems-such as liposomes, dendrimers, polymeric nanoparticles, solid lipid nanoparticles, carbon nanotubes, and metallic nanoparticles-offer benefits like enhanced bioavailability, targeted delivery, improved stability, and reduced side effects. Innovative formulation strategies, including surface functionalization, particle size optimization, and use of biodegradable carriers, support controlled and sustained drug release. Additionally, production in non-aqueous …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 54–67 Read article