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135 articles for “genetic improvement”
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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Valorization of Fruit and Vegetable Wastes for CA Production: A Comprehensive Review with Emphasis on Aspergillus niger Bioprocessing and Future Prospects
Abstract: Citric Acid (CA) is a multifunctional organic acid with diverse industrial applications, recently gaining prominence in polymer and composite science as a green crosslinker, compatibilizer, and functional additive. Conventionally produced through submerged fermentation of refined sugars by Aspergillus niger, industrial CA production faces sustainability challenges due to reliance on food-grade substrates. This review highlights emerging strategies for CA biosynthesis from vegetable and fruit processing residues—including cucumber peels, broccoli stalks, spinach …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 807–822 Read article
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article
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The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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Calf Mortality in the Tropics: Multidimensional Challenges and Implications for Sustainable Dairy Development
Abstract: Calf mortality remains a significant challenge in tropical dairy farming, posing threats to productivity and sustainability. This review explores the multifactorial factors contributing to calf mortality in the tropics, including environmental stress, infectious diseases, nutritional deficiencies, management practices, genetic factors, and social dynamics. Tropical climates, characterized by extreme temperature variations, humidity, and poor shelter, exacerbate stress and compromise calf health. Infectious diseases, such as bacterial, viral, and parasitic infections, coupled …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 7–23 Read article
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Wiskott-Aldrich Syndrome: A Comprehensive Guide
Abstract: Wiskott-Aldrich Syndrome (WAS) is an uncommon genetic disorder inherited through the X chromosome, marked by a combination of immune system deficiencies, eczema, and low platelet counts. This syndrome primarily affects males, leading to significant morbidity and mortality due to recurrent infections, bleeding complications, and autoimmune diseases. Mutations in the WAS gene disrupt the production of the Wiskott-Aldrich Syndrome protein (WASp), crucial for the functioning of immune cells and platelet formation. …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 39–46 Read article
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AI Activity to Enhance Productivity, Creativity, and Sustainable Development of AI in Healthcare
Abstract: The application of artificial intelligence (AI) in healthcare is revolutionizing the industry by fostering both productivity and creative approaches to patient care and medical research. This study explores how artificial intelligence (AI) is reshaping healthcare by streamlining workflows, improving diagnostic precision, and supporting personalized treatment plans. AI-powered technologies are reshaping the way medical professionals approach patient care, providing tools that not only automate routine administrative and clinical tasks but also …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 21–29 Read article
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Plant-Derived Vaccines: A Sustainable Approach to Disease Control for Global Health
Abstract: Plant-based vaccines present a novel and environmentally responsible approach to vaccination, with significant potential for improving both human and animal health. These vaccines are safer and less expensive than traditional vaccine manufacturing methods because they use genetically modified plants to create antigens that elicit an immune response. Plant-based systems offer a potential remedy for traditional vaccines' high production costs and environmental impact, which are growing problems. Plant-derived vaccines have shown …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 17–20 Read article
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Heterosis in Plants
Abstract: It refers to hybrid vigor or heterosis; herein, the offspring expressed better traits than one or both parent lines. This most often manifests in crop breeding as increased yield in F1 hybrids compared with their parents. Developing high-yielding hybrid cultivars across a wider range of crops represents an important strategy for addressing future food security. However, conventional hybrid breeding approaches are fraught with significant challenges in many self-pollinating crops, such …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 21–31 Read article
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Applications of Nanotechnology in Crop Improvement: New Era of Agriculture
Abstract: It represents a transformative force in agriculture, promising to improve the productivity, yield, sustainability, and food security. This review paper focused on the certain advantages of nanoscience and nanotechnology in enhancing the agricultural productivity, disease management, and food safety. By manipulating different materials and objects at the nanoscale, researchers can develop advanced tools such as smart sensors and targeted delivery systems that improve nutrient absorption and combat plant pathogens. By …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 46–54 Read article
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Current Perspectives of Prader -Willi Syndrome: A Multisystem Approach
Abstract: Prader-Willi syndrome (PWS) is a genetic disorder with multisystem involvement, caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region from paternal 15q11-q13 deletions (about 60%) or maternal uniparental disomy 15 or both. It is a complex and contiguous gene disorder which affects the multiple systems with many clinical presentations especially hypothalamic insufficiency. The clinical features are characterized by short stature position, developmental delay, cognitive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 42–48 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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The Role of Bioinformatics in Nursing: Transforming Healthcare through Data-Driven Insights
Abstract: Bioinformatics, an interdisciplinary field combining biology, computer science, and information technology, is increasingly shaping the nursing profession. It offers powerful tools for improving patient care, advancing clinical research, and enabling personalized healthcare through data-driven decision-making. This article examines the integration of bioinformatics into nursing practice, tracing its historical roots from the Human Genome Project to its current applications in genomic medicine, precision healthcare, and population health. Nurses now play a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 18–21 Read article
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Next-Generation mRNA Vaccines: Applications Beyond COVID-19
Abstract: Messenger RNA (mRNA) vaccine technology has become a paradigm shift in contemporary medicine and, with remarkable success in the COVID-19 pandemic, has opened the door to a new wave of vaccines development. In contrast to the traditional vaccine methods, mRNA vaccines are based on the synthetic genetic code that allows host cells to express target antigens, thus eliciting strong humoral and cellular immunity. The speed of development, efficacy, scalability of …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 15–26 Read article
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Practical Strategies to Mitigate Acidosis in Dairy Cattle: Implications of Nutritional, Genetic, and Management Practices
Abstract: Acidosis in dairy cattle remains a critical concern, adversely affecting rumen health, milk production, and overall animal welfare. This study investigates practical strategies to mitigate acidosis through integrated nutritional, genetic, and management approaches. Nutritional strategies emphasize balancing forage-to-concentrate ratios, providing adequate fiber, and utilizing feed additives such as buffers, probiotics, and yeast cultures to stabilize rumen pH. The importance of gradual dietary transitions and monitoring total mixed ration (TMR) composition …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 27–44 Read article
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Diet-Gene Interactions in Farm Animals: Molecular Dynamics, Gene Expressions, Signalling Pathways and Precision Nutrition for Sustainable Productivity
Abstract: Diet-gene interactions represent a central mechanism through which nutrition influences growth, health, and productivity in farm animals. Recent advances in molecular biology and genetics have revealed that nutrients act not only as metabolic substrates but also as signalling molecules capable of modulating gene expression, cellular pathways, and epigenetic regulation. This review synthesizes current knowledge on the molecular dynamics of nutrient utilization in farm animals, with emphasis on nutrigenomic responses, nutrient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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A Novel Approach for Design and Optimization of Slot Antenna for WLAN Applications
Abstract: The simulation, and analysis of a micro-strip fed slot antenna array intended for operation in the 2.4 GHz ISM (Industrial, Scientific, and Medical) band, which is widely used for wireless technologies such as Wi-Fi and Bluetooth. A slot antenna is a type of antenna where a slot (cut or gap) is made on a metal surface, and it radiates electromagnetic waves. Utilizing ANSOFT HFSS software, the antenna's performance is optimized, …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article