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169 articles for “formulation approaches”
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Medicinal Pteridophytes of Himachal Pradesh: Exploring Their Role in Alleviating Respiratory and Gastrointestinal Disorders
Abstract: Pteridophytes, comprising a diverse group of vascular cryptogams, have been widely used in traditional medicine for their medicinal properties. The therapeutic potential of different medicinal pteridophytes in treating gastrointestinal and respiratory conditions is investigated in this study. Their bioactive substances, including flavonoids, alkaloids, tannins, and saponins, which have anti-inflammatory, antibacterial, and antispasmodic properties, are highlighted by both traditional knowledge and recent research. Specific species, such as Adiantum capillus-veneris (maidenhair fern), …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Numerical Simulation of Transient Free Convection in a Rectangular Cavity Filled with Porous Material Using Finite Element Formulations
Abstract: In this study, the finite element method is used to quantitatively explore transient free convection in porous cavities in order to understand the flow characteristics and heat conduction processes in the square cavities. In comparison to an uniform temperature gradient, the left wall is swiftly heated and the right wall is allowed to cool to a specific temperature. The horizontal walls are insulated on both sides. Dimensionless representations of the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 1–10 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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Gastro Retentive Drug Target System: Its Needs, Advantages, Limitation and Approaches
Abstract: Background: Gastro retentive drug delivery systems (GRDDS) address limitations of oral therapy for drugs with poor solubility, instability at intestinal pH, or narrow absorption windows by prolonging gastric residence and increasing contact with the gastric mucosa. Objectives: To review GRDDS approaches—floating systems, mucoadhesive systems, and super porous hydrogels—with emphasis on formulation strategies and polymer–excipient selection to enhance gastric retention, modulate buoyancy/swelling/adhesion, and ultimately improve oral bioavailability and therapeutic outcomes for …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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Formulation, Evaluation, and Stability Studies of a Topical Clotrimazole and Zinc Oxide Suspension with Enhanced Skin Protective Properties
Abstract: Background: Clotrimazole is a well-known antifungal agent frequently used in the treatment of various superficial fungal infections, while Zinc Oxide is a widely accepted skin protectant with soothing, astringent, and antimicrobial properties. Combining these agents in a topical suspension offers a dual therapeutic approach, enhancing both antifungal efficacy and skin protection. Objective: The objective of this study was to formulate, evaluate, and conduct stability studies on topical suspensions containing Clotrimazole …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 22–31 Read article
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Formulation Development and In Vitro Evaluations of Trimetazidine and Clopidogrel Bilayered Tablets
Abstract: The Bilayered tablets consisting of Trimetazidine SR as well as Clopidogrel IR were efficiently prepared by damp granulation technique as well as straight compression approach specifically. The prepared powdered mix (SR) were also preserved the physiochemical residential or commercial properties of tablet computers such as thickness, firmness, weight variant, friability and drug material. The enhanced formula consists of the average thickness of 3.1 ± 0.034, average firmness of 4.2 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 3, 2023 · pp. 29–40 Read article
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An Overview of Examination of Some Basic Raw Materials for Adsorbent on Approach of Pollutant Mitigation and Treatment
Abstract: This research showcases the basic parameters that are required to produce bio-adsorbent suitable for adsorption process and their important role on treatment of contaminated water environment. The overview of the physicochemical parameters of the raw materials used for the production of the adsorbents, the particle size and the mix ratio were identified as a contributing factor to the rate of contaminants mitigation in the system. The effect of water pollution …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 01–16 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Quantitative Approaches to Legal Decision-Making: The Mathematics of Justice
Abstract: The research paper examines the application of quantitative approaches to decision-making in legal systems, presenting the concept of "mathematical justice." As legal systems grow increasingly complex, the adoption of statistical and data-driven methods can provide valuable insights, offering clarity and consistency to judicial processes. By leveraging these methods, courts and policymakers can make more informed, evidence-based decisions, enhancing both fairness and accountability within the justice system. The paper is divided …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 · pp. 27–31 Read article
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Chitosan polymer and composites Hydrogels: An Emerging Approach for Microplastic Elimination from Water
Abstract: Hydrogel is a polymer network which can retain huge volumes of water but still retains its shape because of its special chemical formula. Recently, hydrogels have become an object of great interest for environmental remediation due to the possibility of controlling their physicochemical properties in the case of removal of microplastics. The current work reviews and analyzes the efficiency of application of conventional coagulation systems based on chitosan and new …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Carbon Capture Technologies: Innovations, Challenges, and Environmental Implication
Abstract: This review work provides a comprehensive overview of carbon capture and storage (CCS) technologies, their status, and future directions. It examines various capture methods, including pre-combustion, post-combustion, oxyfuel combustion, and direct air capture, as well as emerging and hybrid technologies such as metal-organic frameworks, ionic liquids, and microencapsulation. The study discusses the limits of current technologies and attempts to point out innovations needed to ameliorate these challenges. It also explores …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 1, 2025 · pp. 7–18 Read article
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Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and Treatment
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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An Overview of Microbial Diversity in the Functions of Wetland Ecosystems
Abstract: Wetlands serve as abundant reservoirs of biodiversity, crucial for the well-being of both humanity and the natural world. They represent the most critical and fertile ecosystem, where water predominantly dictates the environment and the plant and animal species that inhabit it. Wetlands have diverse microbial flora and fauna, which play essential roles in ecosystems. Soil and aquatic microorganisms mediate many processes, such as biogeochemical cycles, waste decomposition, symbiotic relationships, and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 1–14 Read article
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Impact of E-Learning on Secondary Education in Patna District: The Role of Teachers in Supporting Higher Secondary Students during the COVID-19 Crisis
Abstract: This study assesses the impact of e-learning on secondary education in the Patna district during the unprecedented COVID-19 crisis, focusing on the vital role of teachers in supporting higher secondary students. Utilizing a quantitative survey design with a sample of 150 higher secondary teachers from various schools in Patna, the research identifies both the benefits and significant challenges of the rapid transition to digital education. The findings confirm a major …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 1, 2026 · pp. 28–32 Read article