Search
116 articles for “biological data”
-
Comprehensive Review of Kojic Acid and Its Derivatives: Biological Activities, Safety, and Therapeutic Potential in Depigmentation
Abstract: There are several uses for kojic acid in human medicine, particularly in depigmentation. Additionally, derivatives of it are suggested to enhance efficacy, avoid side effects, and stop chemical degradation. With an eye toward human use and an attempt to clarify the action mechanisms, the goal of this study was to review the most recent scientific literature regarding the biological activities and safety information of kojic acid or its derivatives. During …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 45–53 Read article
-
AI-Driven Innovation in Biomaterials: Predictive Modeling and Design for the Future
Abstract: The integration of artificial intelligence (AI) is revolutionizing the field of biomaterials, paving the way for innovative approaches in their development and production. This paper examines the connection between AI and biomaterials, emphasizing the substantial impact of predictive modeling on the evolution of the field. By examining recent research and cutting-edge uses, the document shows how AI-powered predictive modeling has revolutionized biomaterial design, marking a period of unparalleled precision and …
Published in Trends in Machine design · Vol. 11, Issue 3, 2024 · pp. 25–35 Read article
-
In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
-
Histoplasma capsulatum (Dimorphic Fungus) in India: Biological Features, Virulence Mechanisms, and Clinical Implications of Histoplasmosis.
Abstract: Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Infection is acquired primarily by inhalation of infectious microconidia and may range from asymptomatic infection to severe disseminated disease. Although histoplasmosis has classically been associated with the river valleys of the Americas, it is being increasingly recognized in Asia, including India, where it frequently mimics tuberculosis, leishmaniasis, lymphoma, and leprosy, resulting in delayed diagnosis and treatment. Cutaneous …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 38–48 Read article
-
Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
-
From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
-
Life Sciences in the 21st Century: New Ideas and Their Effects
Abstract: The life sciences have made huge strides in the 21st century, thanks to quick progress in genomics, biotechnology, and computational biology. New technologies like gene editing, personalised medicine, and synthetic biology have changed the way we think about living systems and changed the way we do things in healthcare, farming, and managing the environment. Combining big data and artificial intelligence has sped up discoveries even further, making it possible to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
-
Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
-
Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
-
Sustainable Cotton Crop Productivity through Precision Weed Detection: A Deep Learning-Based Approach with UAV Integration
Abstract: Weeds present a major challenge to crop productivity by competing with crops for vital resources, including water, sunlight, and nutrients, often resulting in significant yield reductions. On a global scale, weeds are responsible for approximately 13.2% of annual crop losses, a quantity sufficient to feed nearly one billion people. These invasive plants disrupt agricultural systems and adversely impact crop yields. Given their uneven distribution in fields, ground or aerial robots …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 19–26 Read article
-
Innovative Biosensor Applications in Petroleum Industry for Enhanced Monitoring and Safety Measures
Abstract: The petroleum industry is fundamental to the global economy, providing the energy and raw materials that drive modern society. However, this industry faces a myriad of challenges, including ensuring the safety of operations, monitoring critical processes effectively, and minimizing environmental impacts. Traditional monitoring techniques, while valuable, often fall short in delivering real-time data and comprehensive insights into operational parameters. These limitations can result in delayed responses to potential hazards and …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–13 Read article
-
Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
-
How Microfluidics Are Used in Modern Science: Lab-on-A-Chip
Abstract: Microfluidics has changed modern research by making lab-on-a-chip (LOC) technologies that combine multiple lab functions into small, portable devices. These little platforms make it easier to correctly handle small amounts of fluid, which saves time, money, reagents, and automation. This article talks about microfluidics and how it helps LOC technology go forward in all areas of science. We look at important uses of biomedical diagnostics, drug development, environmental monitoring, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 35–48 Read article
-
Bayesian Optimization–Driven Operating Parameter Tuning for Maximizing Methane Yield in Anaerobic Digestion
Abstract: To achieve maximum methane production in an anaerobic digestion (AD) process, a combination of various operational parameters must be tuned nonlinearly in the digestion ecosystem. The conventional trial and error optimization methods are slow, resource consuming, and in most instances, cannot model the intricate parameter interaction in biogas production. The current work introduces a Bayesian Optimization-based model to optimize the set of conditions to maximize the level of methane produced …
Published in International Journal of Energy and Thermal Applications · Vol. 4, Issue 1, 2026 · pp. 1–8 Read article
-
Use of AI Tools to Create New Drugs
Abstract: The emergence of artificial intelligence in pharmaceutical research [in drug discovery] is a revolution in pharmaceutical research, often combining computational methods with traditional research methods to solve problems. This review article describes various applications of artificial intelligence at various stages of drug development and highlights significant advances and approaches. He explores the critical role of intelligence in drug design, polypharmacology, drug synthesis, drug repurposing, and prediction of drug properties, such …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 22–49 Read article
-
Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article
-
The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
-
Integration of Biosensors in Robotic Systems for Enhanced Environmental Monitoring
Abstract: Biosensors are analytical devices that use biological components, such as enzymes, antibodies, or nucleic acids, to detect specific chemical or biological substances. They have shown great potential in various fields, particularly in environmental monitoring, due to their sensitivity, specificity, and ability to provide real-time data. Integrating biosensors with robotic systems combines the strengths of both technologies, allowing for efficient data collection in remote, hard-to-reach, or hazardous environments. This integration enables …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 3, 2024 · pp. 38–49 Read article
-
Phytomedicine in 21st century: challenges, innovations & future directions
Abstract: Phytomedicine, the use of plant-derived substances for therapeutic purposes, has experienced significant advancements and challenges in the 21st century. This review explores the current state of phytomedicine, highlighting its advantages, such as natural ingredients, fewer side effects, and cultural acceptance, as well as its disadvantages, including variable quality, lack of standardization, and limited research. The challenges faced by phytomedicine are discussed, focusing on issues of standardization, regulatory discrepancies, scientific evidence …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 86–95 Read article
-
Sustainable Advances in Oral Pathology: The Impact of Artificial Intelligence
Abstract: Oral cavity cancers constitute about 4% of all malignant neoplasms. More than 9,900 new cases are reported from the developed countries yearly, and the 5-year mortality rate is higher than 39%. In Europe, the highest rates occur in Hungary, Croatia, and other Central and Eastern European countries; high levels are also seen in India, Pakistan, and Bangladesh. The management of endosseous pathologies presents considerable challenges because they often exhibit no …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 24–27 Read article