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136 articles for “Metabolic Response”
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Isolation, Identification and Molecular Cloning of Chitinase Gene in Bacteria Isolated from Crustacean Wastes
Abstract: This research envisaged cloning of genes encoding chitinases in bacteria isolated from crustacean wastes and its transformation in E.coli by TOPO cloning method for complete sequencing of partial gene. Chitin and chitinolytic enzymes are gaining importance for their biotechnological applications. Particularly, chitinases are used in both agricultural, industrial applications and also in human health care. The chitinases are present in chitin-containing microorganisms, bacteria and plants with a diversity of roles, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 17–20 Read article
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Temporal Shifts in Forage Quality: Stage of Maturity, Biomass Yield, Performance Matrix, and Ecosystem Responses
Abstract: Forage quality is a key determinant of livestock productivity and environmental sustainability, with its dynamics closely linked to the stage of maturity, biomass yield, and broader ecosystem interactions. This study explores the temporal shifts in forage quality throughout its growth cycle, emphasizing the effects of maturity on nutrient composition, digestibility, and overall biomass yield. The relationship between these factors and their impact on animal performance, including milk yield, growth, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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Beyond Chemotherapy: The Promise of Immunotherapy in Cancer Care and Advancements in Cancer Therapy
Abstract: Recent advances in cancer immunotherapy harness the immune system to precisely target cancer. These include the use of immunosuppressive agents, NK cell recovery, changes in tumor microenvironment metabolic, and aging to achieve a positive tumor response The article explores how the body development of the immune system in the late 19th century, highlighting milestones such as the discovery and FDA approval of IL2. Different categories of immunology are explored, from …
Published in Research and Reviews : A Journal of Immunology · Vol. 13, Issue 2, 2023 · pp. 22–37 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article
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TOXICOLOGY: Present-Day Difficulties for Investigating Safety Science and Target Safety Evaluation of Major Human Hepatocytes
Abstract: Preclinical toxicology has developed into a more thorough understanding of toxicity pathways from its descriptive beginnings. Technological developments have made it possible to forecast safety occurrences, mitigate adverse effects, and create safety biomarkers. Because they are able to self-renew and specialize into different types of human body cells, stem cells are currently being employed for in vitro toxicological applications. However, as compared to primary human hepatocytes, stem cell-derived HLCs perform …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 31–40 Read article
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Cognitive Impairment in Alzheimer’s Disease
Abstract: Alzheimer's disease (AD) is a condition that leads to the deterioration of brain cells and is the primary cause of dementia, characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis are the two main theories proposed to explain AD's multifaceted nature. Characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Biochemical Changes in Chickpea (Cicer arietinum L.) Plants Induced by Flooding
Abstract: Flooding is a significant environmental stressor that affects the growth, development, and productivity of chickpea (Cicer arietinum L.), a crucial pulse crop grown worldwide, especially in India. This study investigates the biochemical changes in chickpea plants subjected to prolonged and sudden flooding. Key parameters analyzed include carbohydrate metabolism, protein content, chlorophyll levels, amylase activity, and proline accumulation. Results show that flooding significantly reduces total sugar content in leaves, stems, and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–9 Read article
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Morphological, Physiological, Biochemical & Molecular Response Of Bell Pepper (Capsicum spp.) Under Salt Stress
Abstract: Bell pepper (Capsicum spp.) is an important vegetable crop known for its high nutritional value, medicinal uses, and various industrial applications. However, salinity stress is a major challenge that limits its growth, productivity, and quality, especially in dry areas. Too much salt in the soil disrupts how plants manage water, causes imbalances in ions, leads to oxidative stress, and negatively impacts morphological, physiological, biochemical, and metabolic processes. These effects significantly …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 2, 2026 Read article
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Analysis of Concept of Aaharpaka in Ayurveda
Abstract: AbstractAyurveda is the most ancient science of life. Ayurveda considers that like all the universal matter, our body is also formed by the Panchamahabutas (five basic elements). In this Panchabhautika Sharira, various processes are going on continuously resulting into loss of various elements. For replacement, one has to consume appropriate Ahara (food). Acharya Charaka states that body is the outcome of food and Agni (factor responsible for digestion) plays important …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2013 · pp. 17–24 Read article
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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Diet-Driven Enhancement of Immune Resilience, Disease Resistance, and Performance: Mechanistic Insights, Nutritional Interventions, and Implications for Sustainable Dairy Development
Abstract: This review synthesizes current knowledge on how dietary strategies can strengthen immune resilience, improve disease resistance, and enhance productive performance in dairy systems while advancing sustainable development. Immune function in dairy cattle is profoundly influenced by nutrition, with energy, protein, essential amino acids, fatty acids, vitamins, minerals, and bioactive compounds playing critical roles in shaping both innate and adaptive immune responses. Suboptimal nutrition impairs immune competence, increases susceptibility to infectious …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 15–24 Read article
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Effect of Salt Stress on Plants: A Review
Abstract: AbstractSalinity may be a major abiotic stress, limiting growth and productivity of plants in many areas of the world. The ability of plants to tolerate salt is set by multiple biochemical pathways that facilitate retention and/or acquisition of water, defend plastid functions, and maintain ion homeostasis. The ability of plants to detoxify radicals underneath conditions of salt stress is perhaps the foremost essential demand. Several salt-tolerant species accumulate methylated metabolites …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 4, Issue 3, 2015 · pp. 35–51 Read article
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Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation
Abstract: Inflammation and rheumatism remain serious health problems in the present era. In the present attempt, the authors developed anti-inflammatory gel which gives benefit of faster permeation for quicker action. This anti-inflammatory gel is very useful for the arthritis patients. For the formulation purpose Boswellia serrata (Shallaki) and Commiphora mukul (Guggul) were selected because very less work has been done on these plants and for synergistic effect known of herbal extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 1–8 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Wound Healing Potential of Medicinal Plants: A Review
Abstract: Wound healing is an integrated cellular and biochemical process of restoring normal structure functions of damaged tissue. Healing is a natural phenomenon by which body itself overcome the damaged to the tissue, but the rate of healing is very slow and chance of microbial infection is high. Improvement in healing process can be accomplished either by shortening the time required for healing or to minimize the undesired consequences. India has …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 2, 2017 · pp. 17–40 Read article
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Diagnostic and Treatment Factors in the Relationship of Co-occurring Bipolar Disorder and Diabetes
Abstract: From an epidemiological standpoint, bipolar disorder and diabetes (Type II diabetes mellitus) exhibits high prevalence and universal distribution, found in men and women of all ages, races, ethnicities, cultures, and socioeconomic groups. Bipolar disorder and diabetes often present as co-occurring medical conditions along with characteristic metabolic, neurochemical, and neuroanatomical changes. The co-occurring conditions are associated with the increased morbidity, chronicity, lower treatment response, and premature mortality. Risk factors for these …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 1, 2016 · pp. 24–30 Read article
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Screening of Some Triterpenoids Isolated from Terminalia arjuna as Inhibitors of Angiotensin Converting Enzyme to Prevent Cardiovascular Diseases
Abstract: Natural products have been shown to present interesting biological and pharmacological activities and are used as chemotherapeutic agents. Plants have historically been used in treating cardiovascular diseases (CVD) and are recognized for their ability to produce secondary metabolites. Secondary metabolites obtained from different plants have been the starting material for designing different drugs. Many useful phytoconstituents have been isolated from Terminalia arjuna. Tannins and flavonoids are responsible for its anticancer …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 3, 2014 · pp. 12–19 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Molecular Characterization of Abiotic Stress Tolerant Chickpea Rhizobia
Abstract: Rhizobacteria are root-colonizing bacteria that form a symbiotic relationship with many legumes. Though parasitic varieties of rhizobacteria exist, the term usually refers to bacteria that form a relationship beneficial for both the parties (mutualism). Such bacteria are often referred to as plant growth promoting rhizobacterias (PGPRs). Though microbial inoculants are indisputably beneficial for crops, they are not widely used in industrial agriculture, as large-scale application techniques have yet to become …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 1, 2016 · pp. 10–13 Read article