Search
175 articles for “Lead compound.”
-
Variation in Extract Yield in Different Parts of Albizia lebbeck
Abstract: Phytochemical screening is an important step which leads to the isolation of new and novel compound. Solvent extract of the plant material with the help of different solvent such as n-hexane, chloroform, alcohol and aqueous revealed that in alcohol and aqueous solvent maximum extract yield obtained in all studied parts. Phytochemical screening analysis of the extract revealed presence of tannins, phenolics, flavonoids, alkaloids, terpenes and steroids in most parts. In …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 2, 2014 · pp. 1–5 Read article
-
Quantitative Determination of Isomeric Components of essential oils by RP-HPLC-PDA in multi-herbal tablets
Abstract: Essential oils are lipophilic and highly volatile secondary plant metabolites, principally mono- and sesquiterpenes. The widespread usage and applications in biopharmaceutics and cosmoceutics of these components drives their quality assessments criteria to be established. Gas chromatography is one of the predominantly used technique for analyzing volatile oils. Although Gas Chromatography employs estimation designs operated at elevated temperatures leading for plausible structural alterations of thermo labile compounds. Hence, a novel gradient …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 19–28 Read article
-
Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation
Abstract: Inflammation and rheumatism remain serious health problems in the present era. In the present attempt, the authors developed anti-inflammatory gel which gives benefit of faster permeation for quicker action. This anti-inflammatory gel is very useful for the arthritis patients. For the formulation purpose Boswellia serrata (Shallaki) and Commiphora mukul (Guggul) were selected because very less work has been done on these plants and for synergistic effect known of herbal extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 1–8 Read article
-
Formulation and Evaluation of Aqueous Azadirachta indica Phytosome
Abstract: A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, and absorption of active chemical constituents in the extract with the help …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 17–30 Read article
-
Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article
-
Acetoxylation of o, m Cresol by Electrochemical Process at Graphite Electrode
Abstract: Electrochemical processes remain unique because of the nature of specific products formed and their mode of formation in which current is a reactive input in place of redox reagents. The high yields of the products can be obtained by designing and optimizing the electrolysis. The ordinary chemical procedures are multi-staged and may result poor yields. Therefore the best way for minimizing the pollution is transformation of conventional chemical processes to …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 8, Issue 3, 2021 · pp. 13–21 Read article
-
Review of the Effect of Imine, Azo, and Formazan Compounds on the Cell Membrane of Bacteria, Fungi, and Their Inhibition of Activity
Abstract: The role of antibiotics is to reduce the resistance of bacterial and fungal cell membranes, thereby penetrating the cell membrane and causing bacterial death. Therefore, researchers have turned to preparing chemical compounds that mimic antibiotics in their ability to eliminate bacteria and microorganisms. Through ongoing research in the field of biological activity, recent decades have witnessed a significant increase in laboratory experiments involving imines, formazan, and other compounds in this …
Published in International Journal of Membranes · Vol. 3, Issue 2, 2026 · pp. 1–10 Read article
-
Review on The effect of Imine, Azo, and Formazan Compounds on The cell Membrane of Bacteria, Fungi and Their inhibition of Activity
Abstract: The role of antibiotics is to reduce the resistance of bacterial and fungal cell membranes, thereby penetrating the cell membrane and causing bacterial death. Therefore, researchers have turned to preparing chemical compounds that mimic antibiotics in their ability to eliminate bacteria and microorganisms. Through ongoing research in the field of biological activity, recent decades have witnessed a significant increase in laboratory experiments involving imines, formazan, and other compounds in this …
Published in International Journal of Membranes · Vol. 3, Issue 2, 2026 Read article
-
Sustaining Investing with SIP: Nurturing Wealth and a Better Future
Abstract: Sustainable Investing with SIP encapsulates the idea of aligning financial goals with responsible investing practices for a more sustainable and prosperous future. SIP (Systematic Investment Plan) signifies a disciplined and systematic approach to investing, where individuals commit to regular contributions towards mutual funds at set intervals, fostering a sustainable and long-term investment strategy. Wealth accumulation implies the gradual growth and nurturing of wealth over time through SIP, emphasizing the patient …
Published in E-Commerce for Future & Trends · Vol. 11, Issue 1, 2024 · pp. 30–35 Read article
-
Preparation, Biochemical Analysis and Sensory Evaluation of Herbal Jam
Abstract: Nowadays, in the world herbal plants have used extensively as food supplements and medicinal purposes as they are cheap and have little side effects. Use of different synthetic preservatives lead to negative health issues. Moreover, the use of synthetic compounds has significant drawbacks, such as increasing cost, handling hazards, concerns about residues on food, and threat to human environment. As a good alternative, herbs replace synthetic preservatives as natural, effective, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 1, 2020 · pp. 17–23 Read article
-
Randomized Clinical Study on Dissolution of Urinary Catheters and Stents Encrustation by an Ayurvedic Compound
Abstract: Encrustation, a crust or hard coating on the surface of urinary catheter and stents, is developed due to the formation of biofilm. Encrustation causes blockage of urinary catheter and leads to reflux of urine, increases renal pressure and ultimately damages renal parenchyma tissues. Present clinical study was designed to evaluate the dissolution activity of an Ayurvedic compound on catheter and stent encrustation and to study the changes seen in serum …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 2, Issue 3, 2013 · pp. 12–24 Read article
-
Long-Term Effects of Feeding High-Lignin Forage to Ruminants: Implications for Productivity, Health, and Sustainability
Abstract: The long-term feeding of high-lignin forage to ruminants can significantly impact various aspects of animal performance, health, and environmental sustainability. Lignin, a complex phenolic compound present in plant cell walls, is indigestible by rumen microbes, leading to reduced fiber digestibility and decreased nutrient utilization. Over time, feeding ruminants with forages high in lignin results in a decline in voluntary dry matter intake (DMI), inefficient energy and protein absorption, and suboptimal …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 30–45 Read article
-
Substituted Thiosemicarbazides as Corrosion Inhibitors for N80 Steel in Hydrochloric Acid
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 N-isonicotinoyl-N′-aryl thiosemicarbazides have been synthesized and employed as corrosion inhibitors for N-80 steel – 15% hydrochloric acid system at 25 ï‚°C. On the basis of their influence on anodic and cathodic polarization behavior, these compounds could be classified as ambiodic inhibitors. Weight loss and electrochemical data leading to their inhibition efficiencies (IEs) suggest that these inhibitors followed adsorption mechanism. Among the …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 3, Issue 2, 2012 · pp. 25–35 Read article
-
Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
-
Structure based pharmacophore Modelling of compounds against Neurodegenerative disorder – Amyotrophic Lateral sclerosis
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle dysfunction, paralysis, and eventually death. These diseases are classified as ALS variations because autopsies reveal abnormalities in both upper and lower motor neurons. These disorders account for only 10% of all adult-onset motor neuron disease cases. Despite extensive research efforts, effective therapeutic interventions for ALS remain limited. Structure-based pharmacophore modeling …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 1–17 Read article
-
Understanding the Dynamics of Biogenic and Anthropogenic Aerosols in the Atmosphere
Abstract: This study explores the complex interactions between marine aerosols, biogenic organic matter, and anthropogenic pollutants, highlighting their implications for climate and air quality. It is established that submicron-sized marine aerosols, primarily of biogenic origin, play a crucial role in cloud condensation nuclei (CCN) concentration, particularly during periods of high biological oceanic activity (HBA). The chemical composition of marine aerosols is significantly influenced by the ocean's annual biological cycle, with seasonal …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 15–22 Read article
-
Thymoquinone Induces Epigenetic Modulation in ROS Dependent Manner
Abstract: Traditional drugs have the ability to treat broad range of diseases by modulating the signaling pathwaysof inflammatory diseases and cancer. Epigenetic modulation is also one of the mechanisms already established as a process of action. Histone deacetylase (HDAC) inhibition leads to changes in gene expression promoting cell death. Thymoquinone (TQ), a bioactive compound from Nigella sativa seeds has shown to have an antineoplastic effect in many cancers. Here we have …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 32–39 Read article
-
Removal of Thiophene from Model Fuel Using Titanium Catalyst
Abstract: Organosulfur compounds like thiophene (Th) and its alkyl derivatives are the major unwanted species present in crude oil fractions as they lead to the formation of sulfur oxides after combustion of the fuel and these oxides of sulfur cause severe environmental damage. Oxidative desulfurization (ODS) process is considered as one of the best alternative deep desulfurization technologies compared to hydrodesulfurization. In the ODS process, the sulfur compounds are oxidized to …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 7, Issue 1, 2016 · pp. 31–36 Read article
-
Hydroponics Culture Regulated Metabolic Variations in Plants of Medicinal Value
Abstract: The current review chiefly brings to light the importance of alternative cultivation strategies for medicinal plants about the effective enhancement of the bioactive substances. The fast-paced society is favoring the need for its cost-effective cultivation and studying the effects thereafter. The mis-steps while collecting the plant from the wild lead to identification issues, genetic and phenotypic variations, variable bioactive substances/secondary metabolites, and toxic compounds. So, cultivation happening in controlled environments, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 14–20 Read article
-
A Review of Toxicity, Genotoxicity and Teratogenicity of Formaldehyde
Abstract: Formaldehyde (FA) is important chemical found outdoor and indoor source, it is commonly used in the production of industrial, laboratories and household fule. Most FA exposure occurs by inhalation or by skin or eye contact. It is rapidly absorbed by lungs, gastrointestinal tract and skin. FA easily reacts with amino group in molecular compounds such as proteins and nucleic acid; these reactions caused alterations in tissues and leading to toxicity …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 9–18 Read article