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105 articles for “Intra”
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Passive Digital Phenotyping for Longitudinal Burnout and Occupational Mental Health Surveillance: A Transformer-Based Explainable Deep Learning Approach Using Smartphone Behavioral Streams
Abstract: Occupational burnout constitutes a pervasive yet chronically under-surveilled public health threat, its insidious temporal evolution rendering episodic self-report instruments structurally inadequate for early detection. This paper introduces BurnoutSense, a passive digital phenotyping framework that continuously harvests eight heterogeneous smartphone behavioral data streams encompassing application usage ecology, communication metadata, geospatial mobility, screen interaction dynamics, inferred sleep rhythmicity, keystroke kinematics, ambient noise exposure, and battery/charging cadence to construct individualized multivariate behavioral signatures …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 44–53 Read article
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Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
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A Comprehensive Review on Male Infertility
Abstract: The failure to attain a clinical pregnancy naturally after one year of unprotected intercourse is termed as infertility. Some of the factors that contribute to Infertility are late marriages, advanced age, genetics and lifestyle to name a few. To tackle this scenario, infertile and sub fertile couples take the aid of assisted reproductive technology. Intra uterine insemination (IUI), In vitro fertilization (IVF), Intra cytoplasmic sperm injection (ICSI), surgical sperm retrieval …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 95–103 Read article
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Domino Reaction for the Synthesis of Nitroolefin Heterocyclic Compound Via Thiazole Formation Followed by Claisen Rearrangement
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into Claisen rearrangement. These substances, which include benzothiazole moiety, are very biologically reactive substances. This novel nitro derivative of 2-((E)-2-nitro-3-phenylallyloxy)-3-ethoxybenzaldehyde was simply treated with mole percentage of 2-(2-(2-aminophenyl) disulfanyl) benzenamine in melt reactive condition. Hence this novel 2-(benzo[d]thiazol-2-yl)-6-ethoxy-4-((E)-2-nitro-3-phenylallyl)phenol core unit compounds was very intrusting and new opportunities for the preparation of closely related to the different [3,3] sigmatropic rearrangements related …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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Recombinant Protein Manufacturing Using Actinomycetes as Host Cells
Abstract: Actinobacteria are highly sought-after for use as cell factories or bioreactors in the pharmaceutical, agricultural, industrial, and environmental sectors. The commercial production of these proteins as recombinants and the biochemical and structural characterization of key proteins have been made possible by the genome sequencing of numerous species of actinomycetes. In this regard, better expression vectors that may be used with actinomycetes are required. As discussed in this article, recent developments …
Published in Research & Reviews: A Journal of Bioinformatics Read article
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Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of Corona Virus Disease (COVID-19)
Abstract: The global pandemic of coronavirus disease- 2019 (COVID-19) continues to pose a threat to people, societies, and economic and healthcare systems. COVID-19s progression and lethality are determine by the host immune system, as is the case with many other diseases. revolutionary idea that has been used to treat other diseases is the control of inflammatory response and cytokine production based on immunonutrition. Some COVID-19 clinical trials are now using zinc, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Investigate an Implementation Study of TI-6AL-4V Lattice-based Scaffold Design Using Finite Element Analysis
Abstract: Implementation studies are advised to determine the effectiveness and performance of bone scaffolding in morphology, which has been demonstrated scientifically. The rehabilitation of bone defects, which is still a complex problem in orthopedic surgery, was the subject of an implementation study we provided. Biomaterial scaffolding porosity and pore size are essential in both in vivo and in vitro bone development. However, it has been linked to various drawbacks, including poor …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 28–35 Read article
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IoT Based Smart Saline Bottle for Healthcare
Abstract: There is a vast development in the Healthcare sector with the enhancement of Technology. The fundamental principle in caring for hospitalized patients is to ensure that each patient receives high- quality treatment, close monitoring, and appropriate nutrition in a timely manner. Saline is one of the most popular intravenous therapies given to patients in every hospital. Usually in all cases, the patients are normally treated by saline first for dehydration …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 7–11 Read article
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An AAV Vector for Inducible Gene Expression Preferentially in Muscles
Abstract: Adeno associated viral (AAV) vectors has been used widely in gene therapy and efforts have been made to improve their utility by adding genetic elements that would enable targeting transgene expression to particular cells or tissues of interest and permitting on/off regulation of expression. In this study, we designed a recombinant AAV9 variant PHP.eB vector with muscle creatine kinase (Mck)-derived enhancers, a synthetic muscle-expression promoter, in combination with a third-generation …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 46–61 Read article
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Wave plate; what is the angle of its central curved segment which provides biomechanically optimal stability for femoral shaft fracture?:A 3-D Finite Analysis
Abstract: Even though intramedullary nailing of femoral shaft fracture is the standard surgical treatment as it is in tibial fracture, plate fixation might be a choice when the fracture involves open growth plate, patients are of shorter stature or have narrow canals. In these cases, fixation techniques with plate and screws, for example, percutaneous procedures involving wave plate, are useful thanks to minimal invasion and preservation of biological environment surrounding the …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 31–43 Read article
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I.V Backflow Prevention Device-Medical Assistance System
Abstract: Our paper aims to revolutionize the way intravenous (IV) blood flow is monitored and managed during infusion therapy. Our solution is a wireless IV drip detection device which is equipped with an intensity sensor on the IV infusion sleeve. This innovative device is designed to monitor the presence of the dripping, reduces the risk of complications of back flow of blood, and provide real-time monitoring of patients receiving IV therapy. …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 374–380 Read article
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Changes of the Function of Interstitial Cells of Cajal and Fecundity During Chronic Salpingitis: Experimental Study
Abstract: We have conducted this study to clarify the changes of the function of interstitial cells of Cajal and fecundity in chronic salpingitis white rat models which are made by infecting its vaginal cavity with Chlamydia. Background: Chlamydial infection is a sexually transmitted disease which is caused by Chlamydia trachomatis. 75% of the fallopian tube disease is thought to be due to anamnesis of asymptomatic Chlamydial infection and those who are …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 23–26 Read article
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Hidradenocarcinoma: A Rare Skin Disease
Abstract: Hidradenocarcinoma (HAC) also known as ‘‘sweat gland tumor” is an aggressive, uncommon, highly malignant, adnexal tumor derived from the intradermal duct of eccrine sweat glands. It is said to be aggressive as it has a high risk of local recurrence (50%–75%) and a high potential to metastasize to nearby lymph nodes or to other distant sites. Hidradenocarcinoma has other recognized variants which are known by different names such as Malignant …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 1–12 Read article
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Deciphering the Pathophysiology of Migraine: Understanding Trigeminovascular System Activity and the Importance of the Gut-Brain Axis
Abstract: Migraine, a prevalent and disabling neurological condition, manifests in distinct phases: premonitory, aura, headache, postdrome, and interictal. Being a primary contributor to adult disability, it presents a substantial economic challenge on a global scale. Even with extensive research spanning centuries, the complete grasp of its root causes continues to evade us. This intricate neurovascular disorder primarily involves local vasodilation of intracranial and extracerebral blood vessels, coupled with simultaneous stimulation of …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 50–61 Read article
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Extended Focused Assessment with Sonography for Trauma (eFAST): A Comprehensive Strategy for Trauma Assessment
Abstract: Trauma is the principal cause of mortality in individuals under 45 years old, with 80% being due to blunt trauma and most deaths arising from hypovolemic shock. Intraperitoneal bleeding occurs in 12% of these cases, making swift identification of trauma critical. The ideal diagnostic test should be fast, accurate, and non-invasive. The adoption of point-of-care ultrasound has profoundly influenced the management and evaluation of trauma patients. This discussion outlines the …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 27–33 Read article
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ISGylation: A Key Host Cellular Defense Mechanism
Abstract: ISGylation, a crucial process of the innate immune response, has garnered increasing attention for its involvement in host's defense against pathogenic infections as well in cancer progression. The key player of ISGylation, ISG15, is stimulated by type I interferons (IFNs). ISG15 covalently binds with viral (influenza NS1A and nucleoproteins) and host (Nedd4, filamin B and CHMP5) target proteins and this interaction inhibits the viral replication process and release of viral …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 68–80 Read article
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Evaluating the Benefits of Lift Procedure for Fistula in Ano: A Peripheral Centre Experience
Abstract: Introduction: Surgery is considered the only definitive treatment for anal fistula. Many surgical techniques have been described. The aim of this study was to communicate the authors’ preliminary experience in the use of a very recent, simplified technique, at a peripheral surgical centre. Patients And Methods: This was a retrospective study of 10 patients of Fistula-in-ano admitted from October 2021 through September 2023. Patients were managed with the ligation of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 17–20 Read article
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CBCT: A Boon in Periodontics – A Review
Abstract: Periodontal disease is an inflammatory disease that can be diagnosed mainly based on clinical signs and symptoms. Two-dimensional radiographs are valuable diagnostic tools as an adjunct to the clinical examination in assessing periodontal bone level. Two-dimensional images do not provide accurate bone levels due to its limitations like projection geometry, superimposition of adjacent anatomic structures, leading to the need for three-dimensional imaging that overcomes these limitations. The diagnosis and treatment …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 7–13 Read article
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Concurrent Infection of Influenza and COVID-19: A Review
Abstract: In December 2019, a novel coronavirus that causes respiratory illnesses was identified in Wuhan, China, and swiftly spread around the world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a virus that spreads via the respiratory system and can cause pneumonia. Members of the Orthomyxoviridae family include influenza viruses. Although there are four genera in this family, influenza is only caused by genera A and B, which are clinically important for …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 7–15 Read article