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International Journal of Biochemistry and Biomolecule Research Original Research

Investigate an Implementation Study of TI-6AL-4V Lattice-based Scaffold Design Using Finite Element Analysis

  1. Amit Bhumarker Department of Mechanical Engineering, Annie Institute of Technology and Research Centre, Chhindwara
  2. Abhishek Singh DepartmentMechanical Engineering, Annie Institute of Technology and Research Centre, Chhindwara

Abstract

Implementation studies are advised to determine the effectiveness and performance of bone scaffolding in morphology, which has been demonstrated scientifically. The rehabilitation of bone defects, which is still a complex problem in orthopedic surgery, was the subject of an implementation study we provided. Biomaterial scaffolding porosity and pore size are essential in both in vivo and in vitro bone development. However, it has been linked to various drawbacks, including poor effective damping, low amounts of deformation, poor capability for absorbing energy, and mismatched bone strength and Young’s modulus (E). Therefore, metallic materials like titanium and its alloy have been studied to treat bone deformities. The research studied the mechanical characteristics of four distinct unit-cell-based architectural scaffolds. Biomaterial scaffolds with predetermined pore size and porosity were created using IntraLattice and Blender 3D software. To determine the Johnson-Cook model’s effectiveness in predicting the mechanical behavior of scaffold structures, quasi-static finite element (FE) analysis simulations using commercial CAE software were conducted. Similar to human cortical bone, the mechanical characteristics of yield strength (YS) and ultimate Young’s modulus (E) were examined. Between 2.59 and 7.65 GPa was determined to be the elastic modulus based on finite element studies.

Keywords

References (24)

  1. Miao X, Sun D. Graded/Gradient Porous Biomaterials. Materials. 2009;3(1):26-47. doi:10.3390/ma3010026
  2. Wally Z, Van Grunsven W, Claeyssens F, Goodall R, Reilly G. Porous Titanium for Dental Implant Applications. Metals. 2015;5(4):1902-1920. doi:10.3390/met5041902
  3. Matassi F, Botti A, Sirleo L, Carulli C, Innocenti M. Porous metal for orthopedics implants. Clin Cases Miner Bone Metab. 2013;10(2):111–5.
  4. Ryan GE, Pandit AS, Apatsidis DP. Porous titanium scaffolds fabricated using a rapid prototyping and powder metallurgy technique. Biomaterials. 2008;29(27):3625-3635. doi:10.1016/j.biomaterials.2008.05.032
  5. Ahsan MN, Paul CP, Kukreja LM, Pinkerton AJ. Porous structures fabrication by continuous and pulsed laser metal deposition for biomedical applications; modelling and experimental investigation. Journal of Materials Processing Technology. 2011;211(4):602-609. doi:10.1016/j.jmatprotec.2010.11.014
  6. Vesenjak M, Ren Z. Yielding and post-yield behaviour of closed-cell cellular materials under multiaxial dynamic loading. Met Mater Int. 2016;22(3):435–42. doi:10.1007/s12540–016–5550–7.
  7. Buciumeanu M, Palaghian L, Miranda AS, Silva FS. Fatigue life predictions including the Bauschinger effect. International Journal of Fatigue. 2011;33(2):145-152. doi:10.1016/j.ijfatigue.2010.07.012
  8. Wally Z, Van Grunsven W, Claeyssens F, Goodall R, Reilly G. Porous Titanium for Dental Implant Applications. Metals. 2015;5(4):1902-1920. doi:10.3390/met5041902
  9. Levine B. A new era in porous metals: applications in orthopaedics. Advanced Engineering Materials. Sep 2008; 10(9): 788-792..
  10. Dabrowski B, Swieszkowski W, Godlinski D, Kurzydlowski KJ. Highly porous titanium scaffolds for orthopaedic applications. Journal of biomedical materials research Part B: Applied biomaterials. Oct 2010; 95(1): 53-61.
  11. Yan C, Hao L, Hussein A, Raymont D. Evaluations of cellular lattice structures manufactured using selective laser melting. International Journal of Machine Tools and Manufacture. 2012;62:32-38. doi:10.1016/j.ijmachtools.2012.06.002
  12. Ashby M, Evans A, Fleck N, Gibson L, Hutchinson J, Wadley H, et al. Metal Foams: A Design Guide. Applied Mechanics Reviews. 2001;54(6):B105-B106. doi:10.1115/1.1421119
  13. Nouri A, Hodgson PD, Wen C. Biomimetic porous titanium scaffolds for orthopedic and dental applications. Published online; 2010. p. 415–51.
  14. Oladapo BI, Zahedi SA, Adeoye AOM. 3D printing of bone scaffolds with hybrid biomaterials. Composites Part B: Engineering. 2019;158:428-436. doi:10.1016/j.compositesb.2018.09.065
  15. Oladapo BI, Zahedi SA, Ismail SO, Olawade DB. Recent advances in biopolymeric composite materials: Future sustainability of bone-implant. Renewable and Sustainable Energy Reviews. 2021;150:111505. doi:10.1016/j.rser.2021.111505
  16. Oladapo BI, Ismail SO, Adebiyi AV, Omigbodun FT, Olawumi MA, Olawade DB. Nanostructural interface and strength of polymer composite scaffolds applied to intervertebral bone. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2021;627:127190. doi:10.1016/j.colsurfa.2021.127190
  17. Oladapo BI, Zahedi SA, Omigbodun FT. A systematic review of polymer composite in biomedical engineering. European Polymer Journal. 2021;154:110534. doi:10.1016/j.eurpolymj.2021.110534
  18. Oladapo BI, Zahedi SA, Ismail SO. Mechanical performances of hip implant design and fabrication with PEEK composite. Polymer. 2021;227:123865. doi:10.1016/j.polymer.2021.123865
  19. Oladapo BI, Zahedi SA. Improving bioactivity and strength of PEEK composite polymer for bone application. Materials Chemistry and Physics. 2021;266:124485. doi:10.1016/j.matchemphys.2021.124485
  20. Oladapo BI, Zahedi SA, Ismail SO, Omigbodun FT. 3D printing of PEEK and its composite to increase biointerfaces as a biomedical material- A review. Colloids and Surfaces B: Biointerfaces. 2021;203:111726. doi:10.1016/j.colsurfb.2021.111726
  21. Oladapo BI, Zahedi SA, Ismail SO, Omigbodun FT, Bowoto OK, Olawumi MA, et al. 3D printing of PEEK–cHAp scaffold for medical bone implant. Bio-Des Manuf. 2021;4(1):44–59. doi:10.1007/s42242–020–00098–0.
  22. Oladapo BI, Ismail SO, Bowoto OK, Omigbodun FT, Olawumi MA, Muhammad MA. Lattice design and 3D-printing of PEEK with Ca10(OH)(PO4)3 and in-vitro bio-composite for bone implant. International Journal of Biological Macromolecules. 2020;165:50-62. doi:10.1016/j.ijbiomac.2020.09.175
  23. Oladapo BI, Obisesan OB, Oluwole B, Adebiyi VA, Usman H, Khan A. Mechanical characterization of a polymeric scaffold for bone implant. J Mater Sci. 2020;55(21):9057–69. doi:10.1007/s10853–020–04638-y.
  24. Merkt S, Hinke C, Bültmann J, Brandt M, Xie YM. Mechanical response of TiAl6V4 lattice structures manufactured by selective laser melting in quasistatic and dynamic compression tests. Journal of Laser Applications. 2014;27(S1). doi:10.2351/1.4898835