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75 articles for “Design-Down Approach”
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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AI Driven IoT Based Decision Making System for Brain wave study: KSK approach for Brain wave study
Abstract: The rapid convergence of Internet of Things (IoT) architectures and deep learning has unlocked unprecedented potential for real-time neuro-diagnostic monitoring. This paper presents a novel framework for an AI-driven IoT ecosystem designed to capture, transmit, and interpret human electroencephalography (EEG) signals with minimal latency. Traditional brain-computer interface (BCI) studies are often constrained by localized computing power and the high dimensionality of neural data. Our proposed architecture integrates low-power EEG sensors …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 Read article
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An Arduino-Based Autonomous Serving Robot with GPS Navigation for Cost-Effective Service Automation
Abstract: Robots built for service are no longer confined to research labs or luxury hotels; they are starting to appear in everyday spaces where speed and consistency make a real difference. In a restaurant, for example, a robot that can deliver meals and clear trays reduces staff workload, while in hospitals it can free nurses from routine errands. Schools, too, can benefit by using such machines for both practical and teaching …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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Agentic AI: Architectures, Types, Capabilities, Mathematical Equations and Governance in the Era of Autonomous Intelligence
Abstract: Agentic Artificial Intelligence (Agentic AI) represents a major advancement in the evolution of intelligent systems by enabling autonomous planning, decision-making, and action execution. Unlike traditional AI models, which are primarily reactive and designed to respond to predefined inputs, Agentic AI systems possess capabilities such as memory, reasoning, goal-oriented planning, tool integration, and dynamic adaptation to changing environments. These characteristics allow them to perform complex, multi-step tasks with minimal human intervention, …
Published in Recent Trends in Mathematics · Vol. 3, Issue 2, 2026 Read article
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Personalized Medicines in Pharmaceutics: Drug Delivery System
Abstract: Pharmaceutics personalized medicine is a developing area that seeks to customize medical interventions for specific patients. Instead of a one-size-fits-all approach, personalized medicine focuses on developing treatments that consider a person’s unique characteristics, such as their genetic makeup, environment, and lifestyle. This allows for more effective treatment outcomes, as drugs are specifically designed to work best for each patient, reducing side effects and improving therapeutic results. In pharmaceutics, this involves …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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CRISPR, Recombinant DNA, and LAMP-Based Platforms for Monkeypox: Emerging Tools for Diagnosis and Therapeutic Development
Abstract: Monkeypox, a zoonotic viral infection caused by the Monkeypox virus of the Orthopoxvirus genus, has recurred as a worldwide public health concern after recent outbreaks outside of its classical endemic areas in Central and West Africa. The resurgence has demanded a thorough reassessment of its epidemiology, mode of transmission, and clinical presentation. In light of these challenges, recombinant DNA technology (rDNA) has emerged as a candidate for developing vaccines, diagnostics, …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 7–28 Read article
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Innovations in Mineral Science and Engineering for Sustainable Resource Development
Abstract: The growing global demand for mineral resources, coupled with increasing environmental and social concerns, has intensified the need for sustainable approaches in mineral science and engineering. Traditional mining and mineral processing practices, while essential for industrial development, are often associated with high energy consumption, resource depletion, and environmental degradation. In response, recent innovations in mineral science and engineering have focused on improving resource efficiency, minimizing environmental impact, and ensuring long-term …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 31–36 Read article
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Hydroponics and Aeroponics in Modern Horticulture: A Review of System Designs and Benefits
Abstract: The quest for efficient and sustainable farming methods around the world has prompted the growing use of soilless cultivation methods like hydroponics and aeroponics. As traditional farming methods face challenges like soil degradation, water scarcity, and climate change, these advanced systems provide viable alternatives that maximize productivity while minimizing resource usage. Hydroponics and aeroponics enable precise control over nutrient delivery, water consumption, and environmental conditions, making them highly efficient solutions …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 1, 2025 · pp. 18–22 Read article
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Divorced Women Attitudes Towards Remarriage: A Qualitative Approach
Abstract: The current study aimed to investigate the attitudes of divorced women regarding remarriage and to comprehend the diverse factors that shape their viewpoints. The research population comprised divorced women, and a purposive sampling method was employed to select participants. Data were collected from ten divorced women through semi-structured interviews, allowing for in-depth exploration of personal experiences and viewpoints. A qualitative research design was adopted to capture the complexity of individual …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 1–14 Read article
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Diet Mate: A Personal Nutrition and Health Tracking App
Abstract: The rising prevalence of chronic health conditions, including obesity, diabetes, and hypertension, has become a significant global health challenge. These conditions are often linked to poor dietary habits, which makes diet management a critical component of disease prevention and management. Traditional dietary approaches, such as generic meal plans or standard consultations with nutritionists, often fail to address the unique and evolving needs of individuals, especially those with specific health concerns. …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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A Study on “Clean" in Beauty: A Machine LearningApproach to Ingredient Transparency and ConsumerTrust
Abstract: The burgeoning "clean beauty" market, while driven by consumer demand for safer and more sustainable products, is plagued by ambiguous definitions and the pervasive challenge of "greenwashing". This ambiguity hinders informed consumer choices and complicates brand authenticity. This study addresses these complexities by developing a novel machine learning (ML) framework designed to objectively analyze cosmetic ingredient lists, classify products based on their "cleanliness" profile, and identify key ingredient attributes that …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Passive Digital Phenotyping for Longitudinal Burnout and Occupational Mental Health Surveillance: A Transformer-Based Explainable Deep Learning Approach Using Smartphone Behavioral Streams
Abstract: Occupational burnout constitutes a pervasive yet chronically under-surveilled public health threat, its insidious temporal evolution rendering episodic self-report instruments structurally inadequate for early detection. This paper introduces BurnoutSense, a passive digital phenotyping framework that continuously harvests eight heterogeneous smartphone behavioral data streams encompassing application usage ecology, communication metadata, geospatial mobility, screen interaction dynamics, inferred sleep rhythmicity, keystroke kinematics, ambient noise exposure, and battery/charging cadence to construct individualized multivariate behavioral signatures …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 44–53 Read article
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Forecasting Climate-Driven Healthcare Demand in Agricultural Regions: A Multi-Modal AI Approach
Abstract: The rapidly increasing instability of world climatic regimes has made past meteorological thresholds irrelevant, especially in the agricultural areas where monetary stability and well-being of humans are closely intertwined with an environmental situation. The more the frequency of 1 in every 1000-year events, i.e., heatwaves and catastrophic flooding increase, the greater the rural healthcare systems are in crisis, i.e., unable to predict a surge in demand because of data scarcity, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 28–38 Read article
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A review on Design of Gene Therapy and Its Potential for Craniofacial Regeneration
Abstract: One of the most talked-about topics of the 21st century is gene therapy, which holds the promise of treating many diseases. Current gene therapy research explores a wide range of potential treatments, such as enhancing the body’s immune response to tumors, promoting the formation of new blood vessels in the heart to mitigate heart attacks, and preventing HIV replication in AIDS patients. Gene therapy involves the introduction, alteration, or replacement …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 6–12 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications,challenges, current trends, and reseach opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Total-internal-reflection-based optical rotation quasi-phase-matching for efficient second-harmonic generation in Cadmium Germanium Arsenide crystal
Abstract: This study investigates a total-internal-reflection (TIR)-based optical rotation quasi-phase-matching (ORQPM) approach for second harmonic generation within a cadmium germanium arsenide crystal slab. The crystal is coated with a thin film of yttrium oxide to facilitate precise control over phase shifts between p- and s-polarized light upon reflection at the slab-film interface. By leveraging the interplay between TIR- induced optical rotation and fractional QPM effects at designated bounce points, the configuration …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 Read article
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Environmental Horticulture: Pathways to Sustainability and Climate Resilience
Abstract: Environmental horticulture represents a multidisciplinary approach that combines plant cultivation, landscape management, and sustainable practices to address pressing global environmental challenges while promoting ecological and societal well-being. This study delves into key themes such as sustainable horticulture, urban agriculture, vertical farming, hydroponics, aquaponics, and their significant contributions to biodiversity conservation, soil and water preservation, and climate change mitigation. The integration of innovative practices like green roofs, living walls, and biophilic …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 33–38 Read article