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139 articles for “Clinical indications”
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Automated Blood Cell Counting and Disease Identification Using Image Processing: Implications for Polymer Composite- Based Biomedical Diagnostic Devices
Abstract: Accurate quantification of blood cells is central to clinical decision-making and to the performance of emerging polymer composite–based diagnostic platforms. This work presents a cost-effective, image-processing pipeline for automated counting of red blood cells (including overlapping cells), white blood cells, and platelets from Leishman-stained peripheral blood smears, and articulates its relevance to polymer composite microfluidic and biosensor devices. Implemented in Python with OpenCV, the workflow performs grayscale conversion, median/Gaussian denoising, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 262–270 Read article
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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Orthostride: An Internet of Medical Things-Enabled Smart Rehabilitation Footwear System for Real-Time Monitor
Abstract: The orthopedic rehabilitation goal of controlled weight bearing, a stable gait progression, and early recognition of hazardous situations for safe mobility is traditionally met through time, scheduled in-clinic observation and clinician induction, and patient report. In this work, Orthostride, a smart rehabilitation footwear prototype intended to augment postoperative and injury-related lower extremity restoration through continuous sensing, embedded decision logic, local feedback, and remote telemetry, is proposed. This system incorporates force …
Published in International Journal of Electronics Automation · Vol. 4, Issue 2, 2026 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Alzheimer’s Disease Detection Using ML Algorithm
Abstract: A degenerative neurological state of affairs, Alzheimer's disease (AD) gradually impairs cognitive and functional capacities, especially in people over 65. Early AD detection is crucial for efficient management and treatment prep. This study delves into novel approaches for the early detection of AD using non-invasive methods. We've implemented a blend of neuroimaging data analysis and machine learning algorithms to pinpoint markers indicative of the disease during its initial phases. Our …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 53–57 Read article
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A Python-Based Investigation of Clinical Data and Ultrasound Images for PCOS Diagnosis
Abstract: PCOS is a common endocrine disorder that impacts women in their reproductive years characterized by irregular menstrual cycles, hyperandrogenism, and polycystic ovaries. The full diagnostic plan is mainly a combination of a pelvic ultrasound besides blood tests of specific parameters that indicate the presence of PCOS. Since PCOS is a hard-to-diagnose widespread hormonal disorder, blood tests, symptoms, and other parameters with the help of a computer can form a new …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
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Development of Novel Polymeric Articulating Papers for Enhanced Occlusal Contact Assessment in Dentistry
Abstract: Traditional articulating papers, a mainstay in occlusal analysis, often exhibit limitations in consistency and difficulty with quantitative data analysis. This study explores the development of novel articulating papers utilizing advanced polymeric materials. These novel papers aim to address the shortcomings of traditional options by potentially improving: (1) sensitivity and resolution for capturing occlusal contacts, (2) consistency and reproducibility of contact readings, and (3) durability and reusability. The successful development of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1004–1011 Read article
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Versatile Use of the Local Muscle Flaps Pedicled by Gastrocnemius and Hemisoleus Muscle with a Longer Reach for Coverage of Lower Extremity Defects
Abstract: Purpose: This study aims to highlight the clinical usefulness of multiple local muscle flaps pedicled on the gastrocnemius and hemisoleus muscles for managing soft-tissue defects of the lower extremity. The technique was applied to defects involving the distal femur and the distal one-third of the tibia, avoiding the need for free flap reconstruction. Methods: From January 2014 to January 2023, multiple local muscle flaps were planned and utilized for the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 Read article
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Psychological Profile of Patients Undergoing Hemodialysis and Its Association with Physiological Parameters
Abstract: Background: End-stage renal disease (ESRD) is a chronic, progressive condition requiring maintenance hemodialysis, which imposes substantial physiological, psychological, and social burdens on patients. While physiological indicators are routinely monitored during treatment, the influence of psychological factors on these indicators and patients' quality of life remains inadequately explored, particularly in the Indian context. Objective: To investigate the relationship between psychological variables (depression, anxiety, illness intrusiveness, and quality of life) and physiological …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article
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Interfacial Performance and Structural Stability of Repaired vs. Replaced Polymer-Based Composites: A 3-Year Retrospective Analysis of 'Patch-up' Restorative Engineering
Abstract: Objective: This retrospective study aimed to evaluate the clinical longevity and interfacial success of repairing aged polymer-based composites versus complete replacement, focusing on the integration between the existing polymer matrix and the new restorative material. Materials and Methods: A retrospective clinical audit was conducted on 50 cases (n = 50) of posterior restorations with localized defects. The sample was categorized into: Group A (n = 25), where defective sites were …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 180–187 Read article
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Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases
Abstract: Among all the Drug Delivery Systems, Snehpana (~Lipid Based Drug Delivery System) is being widely used because this facilitates uniform distribution and absorption of fat and water-soluble chemical constituents. Due to their effective size-dependent properties and challenges related to the solubility and bioavailability of water-soluble drugs, this system holds a significant advantage. Numerous studies have highlighted the potential of lipid-based formulations in managing chronic and life-threatening diseases. Shatpala ghrit (SG) …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 1–11 Read article
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Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article
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Exploring the Therapeutic Potential of Ilāj-Bil-Ghizā (Dietotherapy) in Depression: A Systematic Review
Abstract: Background: Depression is a common mental health condition characterized by feelings of sadness, diminished interest in activities, and physical symptoms that disrupt daily activities functioning. Emerging research indicates that nutrition and dietary habits can significantly influence the management of depression. This review aims to explore the connection between diet and mental health, highlighting how nutritional approaches may complement traditional treatments for depression. Objective: This review aims to evaluate the relationship …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 10–18 Read article
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A Clinical Study on Comparing the Efficacy of Areca Catechu Mother Tincture with Areca Tea in Control of Blood Sugar Level Among Healthy Individuals
Abstract: Areca tea of Nivedan Nimpe is trending among diabetic group as preventive and curative diet. Areca Catechu is one of the Indian homoeopathic drugs. There is no authentic literature source to indicate the action of Areca against diabetes, so authors have investigated immediate action on blood sugar level among healthy individuals. Selection of volunteers was done on the basis of inclusion and exclusion criteria. Volunteers were randomly divided into three …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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Examining the Medicinal Role of Alum in Unani Medicine: An Overview of Traditional Uses and Scientific Investigations
Abstract: Alum, also known as Shibb-e-Yamani, is a crystalline substance devoid of color, transparent, and lacking any scent. It possesses a sweetish astringent flavor and is categorized as a hydrated double salt. Typically, it comprises aluminum sulfate, water molecules as part of its structure, and the sulfate of another element. Frequently, it's found mixed with impurities. To render it suitable for medicinal usage, a process involves dissolving it in boiling water, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 1–9 Read article
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Quantitative Image-Based Assessment of Degradation Patterns in Polymer-Based Medical Implants
Abstract: Polymer-based medical devices are widely used in clinical practice, where long-term material degradation can compromise performance and patient safety. Traditional polymer degradation studies predominantly rely on laboratory-based experiments, which often fail to capture real-world operational and usage conditions. In this study, a multimodal, data-driven framework is proposed for the quantitative assessment of degradation patterns in polymer-based medical devices using publicly available clinical failure data. Structured operational parameters, including cumulative usage …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1510–1518 Read article
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Multimodal Disease Detection Using Deep Learning
Abstract: Artificial Intelligence (AI) is playing an increasingly pivotal role in modern healthcare, particularly in improving the speed and accuracy of disease detection. With the evolution of Machine Learning (ML), Deep Learning (DL), and high-performance computing, AI-based solutions are now capable of processing extensive medical datasets, ranging from patient records to diagnostic images, with remarkable efficiency. These systems offer immense potential for early intervention, improved clinical decision-making, and alleviating pressure on …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 129–139 Read article